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5K7U
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BU of 5k7u by Molmil
Crystal structure of the catalytic domains of Mettl3/Mettl14 complex with SAM
Descriptor: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYLMETHIONINE
Authors:Wang, P, Doxtader, K.A, Nam, Y.
Deposit date:2016-05-26
Release date:2016-07-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Mol.Cell, 63, 2016
5K7M
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BU of 5k7m by Molmil
Crystal structure of the catalytic domains of Mettl3/Mettl14 complex
Descriptor: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14
Authors:Wang, P, Doxtader, K.A, Nam, Y.
Deposit date:2016-05-26
Release date:2016-07-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Mol.Cell, 63, 2016
6L42
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BU of 6l42 by Molmil
Structure of severe fever with thrombocytopenia syndrome virus L protein
Descriptor: MAGNESIUM ION, RNA polymerase
Authors:Wang, P, Lou, Z.
Deposit date:2019-10-15
Release date:2020-05-13
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of severe fever with thrombocytopenia syndrome virus L protein elucidates the mechanisms of viral transcription initiation.
Nat Microbiol, 5, 2020
5K7W
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BU of 5k7w by Molmil
Crystal structure of the catalytic domain of Mettl3/Mettl14 complex with SAH
Descriptor: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Wang, P, Doxtader, K.A, Nam, Y.
Deposit date:2016-05-26
Release date:2016-07-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Mol.Cell, 63, 2016
6IUV
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BU of 6iuv by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 3C11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3C11 Heavy Chain, 3C11 Light Chain, ...
Authors:Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X.
Deposit date:2018-11-30
Release date:2019-01-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294, 2019
4XRU
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BU of 4xru by Molmil
Structure of Pnkp1/Rnl/Hen1 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Wang, P.
Deposit date:2015-01-21
Release date:2015-04-22
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Reconstitution and structure of a bacterial Pnkp1-Rnl-Hen1 RNA repair complex.
Nat Commun, 6, 2015
8WDK
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BU of 8wdk by Molmil
The complex structure of Cul2-VCB-Protac-Wee1
Descriptor: (2S,4R)-1-[(2S)-3,3-dimethyl-2-[3-[4-[4-[4-[[3-oxidanylidene-1-[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]-2-prop-2-enyl-pyrazolo[3,4-d]pyrimidin-6-yl]amino]phenyl]piperazin-1-yl]butoxy]propanoylamino]butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Wang, P, Zhang, T.T.
Deposit date:2023-09-15
Release date:2024-09-18
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structure of Cul2-VCB-Protac-Wee1 complex at 3.6 Angstrom resolution.
To Be Published
6IUT
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BU of 6iut by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody AVFluIgG01
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, AVFluIgG01 Heavy Chain, ...
Authors:Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X.
Deposit date:2018-11-30
Release date:2019-01-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294, 2019
6CKU
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BU of 6cku by Molmil
Solution structure of the zebrafish granulin AaE
Descriptor: Granulin-AaE
Authors:Wang, P, Ni, F.
Deposit date:2018-02-28
Release date:2018-06-13
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Structure dissection of zebrafish progranulins identifies a well-folded granulin/epithelin module protein with pro-cell survival activities.
Protein Sci., 27, 2018
9F0H
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BU of 9f0h by Molmil
cryo-EM structure of carboxysomal mini-shell icosahedral assembly from co-expression of CsoS1C, CsoS4A, and CsoS2-C (T = 9)
Descriptor: Carboxysome assembly protein CsoS2B, Carboxysome shell protein CsoS1C, Carboxysome shell vertex protein CsoS4A, ...
Authors:Wang, P, Marles-Wright, J, Liu, L.N.
Deposit date:2024-04-16
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (1.8 Å)
Cite:Molecular principles of the assembly and construction of a carboxysome shell.
Sci Adv, 10, 2024
8YVC
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BU of 8yvc by Molmil
Cryo-EM structure of carboxysomal midi-shell:icosahedral assembly from CsoS4A/4B/1A/1B/1C/1D and CsoS2 C-terminal co-expression (T = 19)
Descriptor: Carboxysome assembly protein CsoS2B, Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A
Authors:Wang, P, Li, J.X, Li, T.P, Li, K, Ng, P.C, Wang, S.M, Chriscoli, V, Basle, A, Marles-Wright, J, Zhang, Y.Z, Liu, L.N.
Deposit date:2024-03-28
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Molecular principles of the assembly and construction of a carboxysome shell.
Sci Adv, 10, 2024
8YVF
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BU of 8yvf by Molmil
cryo-EM structure of carboxysomal midi-shell: assembly from CsoS4A/4B/1A/1B/1C/1D and CsoS2 C-terminal co-expression (T=9 Q=12)
Descriptor: Carboxysome assembly protein CsoS2B, Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A
Authors:Wang, P, Li, J.X, Li, T.P, Li, K, Ng, P.C, Wang, S.M, Chriscoli, V, Basle, A, Marles-Wright, J, Zhang, Y.Z, Liu, L.N.
Deposit date:2024-03-28
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Molecular principles of the assembly and construction of a carboxysome shell.
Sci Adv, 10, 2024
8YVI
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BU of 8yvi by Molmil
Cryo-EM structure of carboxysomal midi-shell: icosahedral assembly from CsoS4A/4B/1A/1B/1C/1D and CsoS2 C-terminal co-expression (T = 13)
Descriptor: Carboxysome assembly protein CsoS2B, Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A
Authors:Wang, P, Li, J.X, Li, T.P, Li, K, Ng, P.C, Wang, S.M, Chriscoli, V, Basle, A, Marles-Wright, J, Zhang, Y.Z, Liu, L.N.
Deposit date:2024-03-28
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Molecular principles of the assembly and construction of a carboxysome shell.
Sci Adv, 10, 2024
8YVE
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BU of 8yve by Molmil
cryo-EM structure of carboxysomal midi-shell: icosahedral assembly from CsoS4A/4B/1A/1B/1C/1D and CsoS2 C-terminal co-expression (T = 9)
Descriptor: Carboxysome assembly protein CsoS2B, Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A
Authors:Wang, P, Li, J.X, Li, T.P, Li, K, Ng, P.C, Wang, S.M, Chriscoli, V, Basle, A, Marles-Wright, J, Zhang, Y.Z, Liu, L.N.
Deposit date:2024-03-28
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Molecular principles of the assembly and construction of a carboxysome shell.
Sci Adv, 10, 2024
8YXU
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BU of 8yxu by Molmil
Crystal structure of CsoS1A/B (modeled with CsoS1A)
Descriptor: Major carboxysome shell protein CsoS1A
Authors:Wang, P, Li, J.X, Li, T.P, Li, K, Ng, P.C, Wang, S.M, Chriscoli, V, Basle, A, Marles-Wright, J, Zhang, Y.Z, Liu, L.N.
Deposit date:2024-04-03
Release date:2024-12-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular principles of the assembly and construction of a carboxysome shell.
Sci Adv, 10, 2024
8YVD
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BU of 8yvd by Molmil
Cryo-EM structure of carboxysomal midi-shell: icosahedral assembly from CsoS4A/4B/1A/1B/1C/1D and CsoS2 C-terminal co-expression (T = 16)
Descriptor: Carboxysome assembly protein CsoS2B, Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A
Authors:Wang, P, Li, J.X, Li, T.P, Li, K, Ng, P.C, Wang, S.M, Chriscoli, V, Basle, A, Marles-Wright, J, Zhang, Y.Z.
Deposit date:2024-03-28
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Molecular principles of the assembly and construction of a carboxysome shell.
Sci Adv, 10, 2024
4QG6
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BU of 4qg6 by Molmil
crystal structure of PKM2-Y105E mutant
Descriptor: PROLINE, Pyruvate kinase PKM
Authors:Wang, P, Sun, C, Zhu, T, Xu, Y.
Deposit date:2014-05-22
Release date:2015-02-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.207 Å)
Cite:Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
4QG8
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BU of 4qg8 by Molmil
crystal structure of PKM2-K305Q mutant
Descriptor: GLYCEROL, MAGNESIUM ION, MALONATE ION, ...
Authors:Wang, P, Sun, C, Zhu, T, Xu, Y.
Deposit date:2014-05-22
Release date:2015-02-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
5V1D
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BU of 5v1d by Molmil
Complex structure of the bovine PERK luminal domain and its substrate peptide
Descriptor: 12-mer peptide, eIF2AK3 protein
Authors:Wang, P, Li, J, Sha, B.
Deposit date:2017-03-02
Release date:2018-02-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization
J. Biol. Chem., 293, 2018
4QG9
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BU of 4qg9 by Molmil
crystal structure of PKM2-R399E mutant
Descriptor: ACETATE ION, MAGNESIUM ION, Pyruvate kinase PKM
Authors:Wang, P, Sun, C, Zhu, T, Xu, Y.
Deposit date:2014-05-22
Release date:2015-02-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
5SV7
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BU of 5sv7 by Molmil
The Crystal structure of a chaperone
Descriptor: Eukaryotic translation initiation factor 2-alpha kinase 3
Authors:Wang, P, Li, J, Sha, B.
Deposit date:2016-08-04
Release date:2017-03-01
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:The ER stress sensor PERK luminal domain functions as a molecular chaperone to interact with misfolded proteins.
Acta Crystallogr D Struct Biol, 72, 2016
4K2X
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BU of 4k2x by Molmil
OxyS anhydrotetracycline hydroxylase from Streptomyces rimosus
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Polyketide oxygenase/hydroxylase
Authors:Wang, P, Sawaya, M.R, Tang, Y.
Deposit date:2013-04-09
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Uncovering the Enzymes that Catalyze the Final Steps in Oxytetracycline Biosynthesis.
J.Am.Chem.Soc., 135, 2013
4RPP
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BU of 4rpp by Molmil
crystal structure of PKM2-K422R mutant bound with FBP
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, Pyruvate kinase PKM
Authors:Wang, P, Sun, C, Zhu, T, Xu, Y.
Deposit date:2014-10-31
Release date:2015-02-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.585 Å)
Cite:Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
5U2U
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BU of 5u2u by Molmil
Crystal structure of the Hsp104 N-terminal domain from Saccharomyces cerevisiae
Descriptor: Heat shock protein 104
Authors:Wang, P, Li, J, Sha, B.
Deposit date:2016-11-30
Release date:2017-04-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.541 Å)
Cite:Crystal structures of Hsp104 N-terminal domains from Saccharomyces cerevisiae and Candida albicans suggest the mechanism for the function of Hsp104 in dissolving prions.
Acta Crystallogr D Struct Biol, 73, 2017
4QGC
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BU of 4qgc by Molmil
crystal structure of PKM2-K422R mutant
Descriptor: GLYCEROL, POTASSIUM ION, Pyruvate kinase PKM, ...
Authors:Wang, P, Sun, C, Zhu, T, Xu, Y.
Deposit date:2014-05-22
Release date:2015-02-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.296 Å)
Cite:Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015

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