5V1D

Complex structure of the bovine PERK luminal domain and its substrate peptide

Summary for 5V1D

• Entry DOI: 10.2210/pdb5v1d/pdb
• Descriptor: eIF2AK3 protein, 12-mer peptide (3 entities in total)
• Functional Keywords: perk, luminal domain, substrate peptide, complex structure, transferase-substrate complex, transferase/substrate
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 7
• Total formula weight: 150007.92

Authors

Wang, P.,Li, J.,Sha, B. (deposition date: 2017-03-02, release date: 2018-02-14, Last modification date: 2024-03-20)

• Primary citation: Wang, P.,Li, J.,Tao, J.,Sha, B.; The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization; J. Biol. Chem., 293:4110-4121, 2018; PubMed: 29386355; DOI: 10.1074/jbc.RA117.001294

Experimental method

X-RAY DIFFRACTION (2.799 Å)