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6IUT
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS H5 HEMAGGLUTININ GLOBULAR HEAD IN COMPLEX WITH THE FAB OF ANTIBODY AVFLUIGG01
分子名称:AVFluIgG01 Heavy Chain, AVFluIgG01 Light Chain, Hemagglutinin, ...
著者Wang, P., Zuo, Y., Sun, J., Zhang, L., Wang, X.
登録日2018-11-30
公開日2019-01-16
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294, 2019
6IUV
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS H5 HEMAGGLUTININ GLOBULAR HEAD IN COMPLEX WITH THE FAB OF ANTIBODY 3C11
分子名称:Hemagglutinin, 3C11 Light Chain, 3C11 Heavy Chain, ...
著者Wang, P., Zuo, Y., Sun, J., Zhang, L., Wang, X.
登録日2018-11-30
公開日2019-01-16
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294, 2019
6CKU
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SOLUTION STRUCTURE OF THE ZEBRAFISH GRANULIN AAE
分子名称:Granulin-AaE
著者Wang, P., Ni, F.
登録日2018-02-28
公開日2018-06-13
最終更新日2018-10-03
実験手法SOLUTION NMR
主引用文献Structure dissection of zebrafish progranulins identifies a well-folded granulin/epithelin module protein with pro-cell survival activities.
Protein Sci., 27, 2018
4K2X
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OXYS ANHYDROTETRACYCLINE HYDROXYLASE FROM STREPTOMYCES RIMOSUS
分子名称:Polyketide oxygenase/hydroxylase, FLAVIN-ADENINE DINUCLEOTIDE
著者Wang, P., Sawaya, M.R., Tang, Y.
登録日2013-04-09
公開日2013-05-15
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Uncovering the Enzymes that Catalyze the Final Steps in Oxytetracycline Biosynthesis.
J.Am.Chem.Soc., 135, 2013
4QG6
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CRYSTAL STRUCTURE OF PKM2-Y105E MUTANT
分子名称:Pyruvate kinase PKM, PROLINE
著者Wang, P., Sun, C., Zhu, T., Xu, Y.
登録日2014-05-22
公開日2015-02-25
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (3.207 Å)
主引用文献Structural insight into mechanisms for dynamic regulation of PKM2
Protein Cell, 2015
4QG8
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CRYSTAL STRUCTURE OF PKM2-K305Q MUTANT
分子名称:Pyruvate kinase PKM, MAGNESIUM ION, POTASSIUM ION, ...
著者Wang, P., Sun, C., Zhu, T., Xu, Y.
登録日2014-05-22
公開日2015-02-25
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insight into mechanisms for dynamic regulation of PKM2
Protein Cell, 2015
4QG9
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CRYSTAL STRUCTURE OF PKM2-R399E MUTANT
分子名称:Pyruvate kinase PKM, MAGNESIUM ION, ACETATE ION
著者Wang, P., Sun, C., Zhu, T., Xu, Y.
登録日2014-05-22
公開日2015-02-25
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (2.381 Å)
主引用文献Structural insight into mechanisms for dynamic regulation of PKM2
Protein Cell, 2015
4QGC
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CRYSTAL STRUCTURE OF PKM2-K422R MUTANT
分子名称:Pyruvate kinase PKM, POTASSIUM ION, SULFATE ION, ...
著者Wang, P., Sun, C., Zhu, T., Xu, Y.
登録日2014-05-22
公開日2015-02-25
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (2.296 Å)
主引用文献Structural insight into mechanisms for dynamic regulation of PKM2
Protein Cell, 2015
4RPP
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CRYSTAL STRUCTURE OF PKM2-K422R MUTANT BOUND WITH FBP
分子名称:Pyruvate kinase PKM, BETA-FRUCTOSE-1,6-DIPHOSPHATE
著者Wang, P., Sun, C., Zhu, T., Xu, Y.
登録日2014-10-31
公開日2015-02-25
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (2.585 Å)
主引用文献Structural insight into mechanisms for dynamic regulation of PKM2
Protein Cell, 2015
4XRU
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STRUCTURE OF PNKP1/RNL/HEN1 COMPLEX
分子名称:Pnkp1, Rnl, Hen1, ...
著者Wang, P.
登録日2015-01-21
公開日2015-04-22
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Reconstitution and structure of a bacterial Pnkp1-Rnl-Hen1 RNA repair complex.
Nat Commun, 6, 2015
5K7M
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAINS OF METTL3/METTL14 COMPLEX
分子名称:N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14
著者Wang, P., Doxtader, K.A., Nam, Y.
登録日2016-05-26
公開日2016-07-06
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Mol.Cell, 63, 2016
5K7U
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAINS OF METTL3/METTL14 COMPLEX WITH SAM
分子名称:N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYLMETHIONINE
著者Wang, P., Doxtader, K.A., Nam, Y.
登録日2016-05-26
公開日2016-07-06
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Mol.Cell, 63, 2016
5K7W
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF METTL3/METTL14 COMPLEX WITH SAH
分子名称:N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYL-L-HOMOCYSTEINE
著者Wang, P., Doxtader, K.A., Nam, Y.
登録日2016-05-26
公開日2016-07-06
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Mol.Cell, 63, 2016
5SV7
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THE CRYSTAL STRUCTURE OF A CHAPERONE
分子名称:Eukaryotic translation initiation factor 2-alpha kinase 3
著者Wang, P., Li, J., Sha, B.
登録日2016-08-04
公開日2017-03-01
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (3.209 Å)
主引用文献The ER stress sensor PERK luminal domain functions as a molecular chaperone to interact with misfolded proteins.
Acta Crystallogr D Struct Biol, 72, 2016
5U2L
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CRYSTAL STRUCTURE OF THE HSP104 N-TERMINAL DOMAIN FROM CANDIDA ALBICANS
分子名称:Heat shock protein 104
著者Wang, P., Li, J., Sha, B.
登録日2016-11-30
公開日2017-04-19
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.6555 Å)
主引用文献Crystal structures of Hsp104 N-terminal domains from Saccharomyces cerevisiae and Candida albicans suggest the mechanism for the function of Hsp104 in dissolving prions.
Acta Crystallogr D Struct Biol, 73, 2017
5U2U
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CRYSTAL STRUCTURE OF THE HSP104 N-TERMINAL DOMAIN FROM SACCHAROMYCES CEREVISIAE
分子名称:Heat shock protein 104
著者Wang, P., Li, J., Sha, B.
登録日2016-11-30
公開日2017-04-19
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.541 Å)
主引用文献Crystal structures of Hsp104 N-terminal domains from Saccharomyces cerevisiae and Candida albicans suggest the mechanism for the function of Hsp104 in dissolving prions.
Acta Crystallogr D Struct Biol, 73, 2017
5V1D
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COMPLEX STRUCTURE OF THE BOVINE PERK LUMINAL DOMAIN AND ITS SUBSTRATE PEPTIDE
分子名称:eIF2AK3 protein, 12-mer peptide
著者Wang, P., Li, J., Sha, B.
登録日2017-03-02
公開日2018-02-14
最終更新日2018-05-02
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization
J. Biol. Chem., 293, 2018
5YUF
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CRYSTAL STRUCTURE OF PML RING TETRAMER
分子名称:Protein PML, ZINC ION
著者Wang, P., Benhend, S., Wu, H., Breitenbach, V., Zhen, T., Jollivet, F., Peres, L., Li, Y., Chen, S., Chen, Z., de THE, H., Meng, G.
登録日2017-11-22
公開日2018-04-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献RING tetramerization is required for nuclear body biogenesis and PML sumoylation.
Nat Commun, 9, 2018
6A67
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS H5 HEMAGGLUTININ GLOBULAR HEAD IN COMPLEX WITH THE FAB OF ANTIBODY FLD21.140
分子名称:FLD21.140 Heavy Chain, FLD21.140 Light Chain, Hemagglutinin, ...
著者Wang, P., Zuo, Y., Sun, J., Zhang, L., Wang, X.
登録日2018-06-26
公開日2018-08-29
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies.
J. Biol. Chem., 293, 2018
5Z16
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A NOVEL DIMERIC ISOCITRATE DEHYDROGENASE FROM ACINETOBACTER BAUMANNII
分子名称:Isocitrate dehydrogenase, PHOSPHATE ION, MAGNESIUM ION
著者Song, P., Huang, S.P., Wang, P., Zhu, G.P.
登録日2017-12-25
公開日2019-02-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A novel dimeric isocitrate dehydrogenase from Acinetobacter baumannii
To Be Published
4DQZ
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CRYSTAL STRUCTURE OF C-TERMINAL HALF OF BACTERIAL HEN1
分子名称:Methyltransferase type 12
著者Huang, R.H., Wang, P.
登録日2012-02-16
公開日2012-08-01
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DRF
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CRYSTAL STRUCTURE OF BACTERIAL PNKP-C/HEN1-N HETERODIMER
分子名称:Metallophosphoesterase, Methyltransferase type 12, GLYCEROL
著者Huang, R.H., Wang, P.
登録日2012-02-17
公開日2012-08-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair.
Proc.Natl.Acad.Sci.USA, 109, 2012
4E6N
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CRYSTAL STRUCTURE OF BACTERIAL PNKP-C/HEN1-N HETERODIMER
分子名称:Metallophosphoesterase, Methyltransferase type 12, MAGNESIUM ION, ...
著者Huang, R.H., Wang, P.
登録日2012-03-15
公開日2012-08-01
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair.
Proc.Natl.Acad.Sci.USA, 109, 2012
4RZY
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CRYSTAL STRUCTURE OF METALLOPEPTIDASE-LIKE DIMETHYLSULPHONIOPROPIONATE (DMSP) LYASE RLDDDP IN COMPLEX WITH MES
分子名称:Peptidase M24, FE (III) ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
著者Zhang, Y., Wang, P.
登録日2014-12-26
公開日2015-08-05
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Structural and molecular basis for the novel catalytic mechanism and evolution of DddP, an abundant peptidase-like bacterial Dimethylsulfoniopropionate lyase: a new enzyme from an old fold.
Mol.Microbiol., 98, 2015
4RZZ
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CRYSTAL STRUCTURE OF METALLOPEPTIDASE-LIKE DIMETHYLSULPHONIOPROPIONATE (DMSP) LYASE RLDDDP IN COMPLEX WITH PHOSPHATE
分子名称:Peptidase M24, FE (III) ION, PHOSPHATE ION, ...
著者Zhang, Y., Wang, P.
登録日2014-12-27
公開日2015-08-05
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and molecular basis for the novel catalytic mechanism and evolution of DddP, an abundant peptidase-like bacterial Dimethylsulfoniopropionate lyase: a new enzyme from an old fold.
Mol.Microbiol., 98, 2015