Author results

1H0T
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AN AFFIBODY IN COMPLEX WITH A TARGET PROTEIN: STRUCTURE AND COUPLED FOLDING
Descriptor:IMMUNOGLOBULIN G BINDING PROTEIN A, ZSPA-1 AFFIBODY
Authors:Wahlberg, E., Lendel, C., Helgstrand, M., Allard, P., Dincbas-Renqvist, V., Hedqvist, A., Berglund, H., Nygren, P.-A., Hard, T.
Deposit date:2002-06-27
Release date:2003-02-27
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:An Affibody in Complex with a Target Protein: Structure and Coupled Folding
Proc.Natl.Acad.Sci.USA, 100, 2003
3P0N
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HUMAN TANKYRASE 2 - CATALYTIC PARP DOMAIN IN COMPLEX WITH AN INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, 7-bromopyrrolo[1,2-a]quinoxalin-4(5H)-one, ...
Authors:Karlberg, T., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kotenyova, T., Kouznetsova, E., Moche, M., Nordlund, P., Nyman, T., Persson, C., Schutz, P., Sehic, A., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2010-09-29
Release date:2010-10-20
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
Nat.Biotechnol., 30, 2012
3P0P
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HUMAN TANKYRASE 2 - CATALYTIC PARP DOMAIN IN COMPLEX WITH AN INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, 2-[4-(4-fluorophenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one, ...
Authors:Karlberg, T., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kotenyova, T., Kouznetsova, E., Moche, M., Nordlund, P., Nyman, T., Persson, C., Schutz, P., Sehic, A., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2010-09-29
Release date:2010-10-20
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
Nat.Biotechnol., 30, 2012
3P0Q
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HUMAN TANKYRASE 2 - CATALYTIC PARP DOMAIN IN COMPLEX WITH AN INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, N-[2-(4-chlorophenyl)ethyl]-6-methyl[1,2,4]triazolo[4,3-b]pyridazin-8-amine, ...
Authors:Karlberg, T., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kotenyova, T., Kouznetsova, E., Moche, M., Nordlund, P., Nyman, T., Persson, C., Schutz, P., Sehic, A., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2010-09-29
Release date:2010-10-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
Nat.Biotechnol., 30, 2012
2XRF
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CRYSTAL STRUCTURE OF HUMAN URIDINE PHOSPHORYLASE 2
Descriptor:URIDINE PHOSPHORYLASE 2, MAGNESIUM ION, URACIL, ...
Authors:Welin, M., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Der Berg, S., Wahlberg, E., Weigelt, J., Nordlund, P.
Deposit date:2010-09-14
Release date:2010-09-29
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Uridine Phosphorylase 2
To be Published
2XRI
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CRYSTAL STRUCTURE OF HUMAN ERI1 EXORIBONUCLEASE 3
Descriptor:ERI1 EXORIBONUCLEASE 3, MAGNESIUM ION, GLYCEROL
Authors:Welin, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Thorsell, A.G., Tresaugues, L., Van Der Berg, S., Wahlberg, E., Weigelt, J., Nordlund, P.
Deposit date:2010-09-15
Release date:2010-09-29
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Human Eri1 Exoribonuclease 3
To be Published
2XSW
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CRYSTAL STRUCTURE OF HUMAN INPP5E
Descriptor:72 KDA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE, CHLORIDE ION, GLYCEROL
Authors:Tresaugues, L., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., Van Der Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2010-09-30
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Human Inpp5E
To be Published
2YBX
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CRYSTAL STRUCTURE OF HUMAN PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE TYPE-2 ALPHA
Descriptor:PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE TYPE-2 ALPHA, PHOSPHATE ION
Authors:Tresaugues, L., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S., Graslund, S., Karlberg, T., Kotenyova, T., Kouznetsova, E., Nyman, T., Persson, C., Schuler, H., Siponen, M.I., Thorsell, A.G., Wahlberg, E., Weigelt, J., Nordlund, P.
Deposit date:2011-03-30
Release date:2012-01-25
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal Structure of Human Phosphatidylinositol-5-Phosphate 4-Kinase Type-2 Alpha
To be Published
2YF0
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HUMAN MYOTUBULARIN RELATED PROTEIN 6 (MTMR6)
Descriptor:MYOTUBULARIN-RELATED PROTEIN 6, SULFATE ION
Authors:Moche, M., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kotenyova, T., Kouznetsova, E., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., VanDenBerg, S., Wahlberg, E., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2011-03-31
Release date:2011-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Human Mtmr6
To be Published
3OLH
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HUMAN 3-MERCAPTOPYRUVATE SULFURTRANSFERASE
Descriptor:3-mercaptopyruvate sulfurtransferase, SULFATE ION, SODIUM ION
Authors:Karlberg, T., Collins, R., Arrowsmith, C.H., Berglund, H., Bountra, C., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kotenyova, T., Kouznetsova, E., Moche, M., Nordlund, P., Nyman, T., Persson, C., Schutz, P., Sehic, A., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2010-08-26
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human 3-Mercaptopyruvate Sulfurtransferase
To be Published
3P0C
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NISCHARIN PX-DOMAIN
Descriptor:Nischarin, GLYCEROL
Authors:Schutz, P., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Der Berg, S., Wahlberg, E., Welin, M., Weigelt, J., Nordlund, P., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2010-09-28
Release date:2010-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.273 Å)
Cite:Crystal structure of Nischarin PX-domain
to be published
3Q90
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CRYSTAL STRUCTURE OF THE NTF2 DOMAIN OF RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1
Descriptor:Ras GTPase-activating protein-binding protein 1
Authors:Welin, M., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., Van Der Berg, S., Wahlberg, E., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2011-01-07
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1
To be Published
3Q91
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CRYSTAL STRUCTURE OF HUMAN URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE (NUDT14)
Descriptor:Uridine diphosphate glucose pyrophosphatase
Authors:Tresaugues, L., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Thorsell, A.G., Van Der Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2011-01-07
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)
To be Published
3Q93
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CRYSTAL STRUCTURE OF HUMAN 8-OXO-DGTPASE (MTH1)
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION, IMIDAZOLE, ...
Authors:Tresaugues, L., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Thorsell, A.G., Van Der Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2011-01-07
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Human 8-oxo-dGTPase (MTH1)
To be Published
2WWE
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CRYSTAL STRUCTURE OF THE PHOX HOMOLOGY DOMAIN OF HUMAN PHOSPHOINOSITIDE-3-KINASE-C2-GAMMA
Descriptor:PHOSPHOINOSITIDE-3-KINASE, CLASS 2, GAMMA POLYPEPTIDE
Authors:Roos, A.K., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotyenova, T., Kotzch, A., Kraulis, P., Markova, N., Moche, M., Nielsen, T.K., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Svensson, L., Thorsell, A.G., Van Der Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2009-10-22
Release date:2009-11-03
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of the Phox Homology Domain of Human Phosphoinositide-3-Kinase-C2-Gamma
To be Published
2X8A
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HUMAN NUCLEAR VALOSIN CONTAINING PROTEIN LIKE (NVL), C-TERMINAL AAA- ATPASE DOMAIN
Descriptor:NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE, PHOSPHATE ION
Authors:Moche, M., Schuetz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Kraulis, P., Nordlund, P., Nyman, T., Persson, C., Sehic, A., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., VanDenBerg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H.
Deposit date:2010-03-08
Release date:2010-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human Nuclear Valosin Containing Protein Like (Nvl) , C-Terminal Aaa-ATPase Domain
To be Published
3K2I
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HUMAN ACYL-COENZYME A THIOESTERASE 4
Descriptor:Acyl-coenzyme A thioesterase 4, NICKEL (II) ION, CHLORIDE ION
Authors:Siponen, M.I., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-09-30
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human Acyl-coenzyme A thioesterase 4
To be Published
3LLM
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CRYSTAL STRUCTURE ANALYSIS OF A RNA HELICASE
Descriptor:ATP-dependent RNA helicase A, MANGANESE (II) ION, CACODYLATE ION, ...
Authors:Schutz, P., Karlberg, T., Collins, R., Arrowsmith, C.H., Berglund, H., Bountra, C., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H.M., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.
J.Mol.Biol., 400, 2010
3LS8
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CRYSTAL STRUCTURE OF HUMAN PIK3C3 IN COMPLEX WITH 3-[4-(4-MORPHOLINYL)THIENO[3,2-D]PYRIMIDIN-2-YL]-PHENOL
Descriptor:Phosphatidylinositol 3-kinase catalytic subunit type 3, 3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, CHLORIDE ION, ...
Authors:Tresaugues, L., Welin, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kotenyova, T., Kraulis, P., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., Van den Berg, S., Wahlberg, E., Weigelt, J., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2010-02-12
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol
To be Published
3MCF
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CRYSTAL STRUCTURE OF HUMAN DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 3-ALPHA
Descriptor:Diphosphoinositol polyphosphate phosphohydrolase 3-alpha, CITRATE ANION, GLYCEROL
Authors:Tresaugues, L., Welin, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., van der Berg, S., Wahlberg, E., Weigelt, J., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2010-03-29
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human diphosphoinositol polyphosphate phosphohydrolase 3-alpha
To be Published
3MTG
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CRYSTAL STRUCTURE OF HUMAN S-ADENOSYL HOMOCYSTEINE HYDROLASE-LIKE 1 PROTEIN
Descriptor:Putative adenosylhomocysteinase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Wisniewska, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Schutz, P., Thorsell, A.G., Tresaugues, L., van der Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2010-04-30
Release date:2010-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein
TO BE PUBLISHED
3N8E
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SUBSTRATE BINDING DOMAIN OF THE HUMAN HEAT SHOCK 70KDA PROTEIN 9 (MORTALIN)
Descriptor:Stress-70 protein, mitochondrial
Authors:Wisniewska, M., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Schutz, P., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., van der Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2010-05-28
Release date:2010-06-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)
To be published
3N9U
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE 25 KDA SUBUNIT AND THE 59 KDA SUBUNIT (RRM DOMAIN) OF HUMAN CLEAVAGE FACTOR IM
Descriptor:Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 7, GLYCEROL
Authors:Tresaugues, L., Welin, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Moche, M., Nielsen, T.N., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., van der Berg, S., Wahlberg, E., Weigelt, J., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2010-05-31
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im
To be Published
3SE2
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 14 (PARP14/ARTD8) - CATALYTIC DOMAIN IN COMPLEX WITH 6(5H)-PHENANTHRIDINONE
Descriptor:Poly [ADP-ribose] polymerase 14, phenanthridin-6(5H)-one, GLYCEROL, ...
Authors:Karlberg, T., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Graslund, S., Kouznetsova, E., Moche, M., Nordlund, P., Nyman, T., Thorsell, A.G., Tresaugues, L., Weigelt, J., Siponen, M.I., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2011-06-10
Release date:2011-07-06
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.
Nat.Biotechnol., 30, 2012
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 14 (PARP14/ARTD8) - CATALYTIC DOMAIN IN COMPLEX WITH A QUINAZOLINE INHIBITOR
Descriptor:Poly [ADP-ribose] polymerase 14, 2-{[(3-amino-1H-1,2,4-triazol-5-yl)sulfanyl]methyl}-8-methylquinazolin-4(3H)-one
Authors:Karlberg, T., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Edwards, A.M., Ekblad, T., Graslund, S., Kouznetsova, E., Nordlund, P., Nyman, T., Thorsell, A.G., Tresaugues, L., Weigelt, J., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2011-06-28
Release date:2011-07-20
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.
Nat.Biotechnol., 30, 2012
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