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5MF9
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BU of 5mf9 by Molmil
Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide.
Descriptor: RNA-binding protein 5, Survival motor neuron protein
Authors:Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J.
Deposit date:2016-11-17
Release date:2016-12-07
Last modified:2018-01-31
Method:SOLUTION NMR
Cite:Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation
Elife, 5, 2016
2M8D
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BU of 2m8d by Molmil
Structure of SRSF1 RRM2 in complex with the RNA 5'-UGAAGGAC-3'
Descriptor: RNA (5'-R(*UP*GP*AP*AP*GP*GP*AP*C)-3'), Serine/arginine-rich splicing factor 1
Authors:Clery, A, Sinha, R, Anczukow, O, Corrionero, A, Moursy, A, Daubner, G, Valcarcel, J, Krainer, A.R, Allain, F.H.T.
Deposit date:2013-05-17
Release date:2013-07-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
7PCV
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BU of 7pcv by Molmil
Crystal structure of RBM5 RRM1-zinc finger
Descriptor: RNA-binding protein 5, ZINC ION
Authors:Soni, K, Jagtap, P.K.A, Sattler, M.
Deposit date:2021-08-04
Release date:2022-08-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Nat Commun, 14, 2023
7PDV
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BU of 7pdv by Molmil
Crystal structure of RBM5 RRM1-zinc finger in complex with RNA
Descriptor: RNA (5'-R(P*UP*GP*GP*CP*UP*CP*UP*UP*CP*U)-3'), RNA binding motif protein 5 isoform 1, ZINC ION
Authors:Soni, K, Jagtap, P.K.A, Sattler, M.
Deposit date:2021-08-08
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Nat Commun, 14, 2023
2YH1
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BU of 2yh1 by Molmil
Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2019-09-25
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
2YH0
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BU of 2yh0 by Molmil
Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains
Descriptor: SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2019-09-25
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
5MFY
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BU of 5mfy by Molmil
RBM5 OCRE domain
Descriptor: RNA-binding protein 5
Authors:Warner, L.R, Mourao, A, Soni, K, Sattler, M.
Deposit date:2016-11-19
Release date:2016-12-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
Elife, 5, 2016
2PEH
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BU of 2peh by Molmil
Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5
Descriptor: Splicing factor 3B subunit 1, Splicing factor 45
Authors:Corsini, L, Basquin, J, Hothorn, M, Sattler, M.
Deposit date:2007-04-03
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
2PE8
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BU of 2pe8 by Molmil
Crystal structure of the UHM domain of human SPF45 (free form)
Descriptor: Splicing factor 45
Authors:Corsini, L, Basquin, J, Hothorn, M, Sattler, M.
Deposit date:2007-04-02
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
2MJN
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BU of 2mjn by Molmil
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
Descriptor: Nucleolysin TIA-1 isoform p40
Authors:Sattler, M, Wang, I.
Deposit date:2014-01-13
Release date:2014-04-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
Nucleic Acids Res., 42, 2014

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