5MF9

Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide.

Summary for 5MF9

• Entry DOI: 10.2210/pdb5mf9/pdb
• NMR Information: BMRB: 34067
• Descriptor: RNA-binding protein 5, Survival motor neuron protein (2 entities in total)
• Functional Keywords: ocre, poly proline binding domain, smn, alternative splicing, splicing
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : P52756; Nucleus, gem : Q16637
• Total number of polymer chains: 2
• Total formula weight: 8573.16

Authors

Mourao, A.,Sattler, M.,Bonnal, S.,Komal, S.,Warner, L.,Bordonne, R.,Valcarcel, J. (deposition date: 2016-11-17, release date: 2016-12-07, Last modification date: 2018-01-31)

• Primary citation: Mourao, A.,Bonnal, S.,Komal, S.,Warner, L.,Bordonne, R.,Valcarcel, J.,Sattler, M.; Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation; Elife, 5:1-25, 2016; PubMed: 27894420; DOI: 10.7554/eLife.14707

Experimental method

SOLUTION NMR