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2K36
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STRUCTURE ENSEMBLE BACKBONE AND SIDE-CHAIN 1H, 13C, AND 15N CHEMICAL SHIFT ASSIGNMENTS, 1H-15N RDCS AND 1H-1H NOE RESTRAINTS FOR PROTEIN K7 FROM THE VACCINIA VIRUS
Descriptor:Protein K7
Authors:Kalverda, A.P., Thompson, G.S., Vogel, A., Schr der, M., Bowie, A.G., Khan, A.R., Homans, S.W.
Deposit date:2008-04-22
Release date:2008-10-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Poxvirus K7 protein adopts a Bcl-2 fold: biochemical mapping of its interactions with human DEAD box RNA helicase DDX3.
J.Mol.Biol., 385, 2009
2KYA
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SOLUTION STRUCTURE OF THE LEADER SEQUENCE OF THE PATELLAMIDE PRECURSOR PEPTIDE, PATE1-34
Descriptor:Patellamide protein
Authors:Houssen, W.E., Wright, S.H., Kalverda, A.P., Thompson, G.S., Kelly, S.M., Jaspars, M.
Deposit date:2010-05-21
Release date:2010-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Leader Sequence of the Patellamide Precursor Peptide, PatE(1-34).
Chembiochem, 11, 2010
2MZW
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STAPHYLOCOCCUS AUREUS FUSB:EF-GC3 COMPLEX
Descriptor:Elongation factor G, Far1, ZINC ION
Authors:Tomlinson, J.H., Thompson, G.S., Kalverda, A.P., Zhuravleva, A., O'Neill, A.
Deposit date:2015-02-25
Release date:2016-01-27
Method:SOLUTION NMR
Cite:A target-protection mechanism of antibiotic resistance at atomic resolution: insights into FusB-type fusidic acid resistance.
Sci Rep, 6, 2016
2XKS
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PRION-LIKE CONVERSION DURING AMYLOID FORMATION AT ATOMIC RESOLUTION
Descriptor:BETA-2-MICROGLOBULIN
Authors:Eichner, T., Kalverda, A.P., Thompson, G.S., Radford, S.E., Homans, S.W.
Deposit date:2010-07-12
Release date:2011-02-16
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Conformational Conversion During Amyloid Formation at Atomic Resolution.
Mol.Cell, 41, 2011
2XKU
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PRION-LIKE CONVERSION DURING AMYLOID FORMATION AT ATOMIC RESOLUTION
Descriptor:BETA-2-MICROGLOBULIN
Authors:Eichner, T., Kalverda, A.P., Thompson, G.S., Homans, S.W., Radford, S.E.
Deposit date:2010-07-12
Release date:2011-02-09
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Conformational Conversion During Amyloid Formation at Atomic Resolution.
Mol.Cell, 41, 2011
5A46
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FGFR1 IN COMPLEX WITH DOVITINIB
Descriptor:FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B, ...
Authors:Klein, T., Vajpai, N., Phillips, J.J., Davies, G., Holdgate, G.A., Phillips, C., Tucker, J.A., Norman, R.A., Scott, A.S., Higazi, D.R., Lowe, D., Thompson, G.S., Breeze, A.L.
Deposit date:2015-06-05
Release date:2015-08-05
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase.
Nat.Commun., 6, 2015
5A4C
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FGFR1 LIGAND COMPLEX
Descriptor:FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B, ...
Authors:Klein, T., Vajpai, N., Phillips, J.J., Davies, G., Holdgate, G.A., Phillips, C., Tucker, J.A., Norman, R.A., Scott, A.S., Higazi, D.R., Lowe, D., Thompson, G.S., Breeze, A.L.
Deposit date:2015-06-05
Release date:2015-08-05
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase.
Nat.Commun., 6, 2015
3ZD0
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THE SOLUTION STRUCTURE OF MONOMERIC HEPATITIS C VIRUS P7 YIELDS POTENT INHIBITORS OF VIRION RELEASE
Descriptor:P7 PROTEIN
Authors:Foster, T.L., Sthompson, G., Kalverda, A.P., Kankanala, J., Thompson, J., Barker, A.M., Clarke, D., Noerenberg, M., Pearson, A.R., Rowlands, D.J., Homans, S.W., Harris, M., Foster, R., Griffin, S.D.C.
Deposit date:2012-11-23
Release date:2013-09-04
Last modified:2014-02-12
Method:SOLUTION NMR
Cite:Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus P7 as a Viable Class of Antivirals Targeting Virion Release
Hepatology, 59, 2014
2YB5
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STRUCTURE OF THE FUSIDIC ACID RESISTANCE PROTEIN FUSC
Descriptor:PUTATIVE FUSIDIC ACID RESISTANCE PROTEIN, ZINC ION, 1,2-ETHANEDIOL
Authors:Cox, G., Edwards, T.A.
Deposit date:2011-03-01
Release date:2012-01-25
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ribosome Clearance by Fusb-Type Proteins Mediates Resistance to the Antibiotic Fusidic Acid
Proc.Natl.Acad.Sci.USA, 109, 2012
4CRZ
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DIRECT VISUALISATION OF STRAIN-INDUCED PROTEIN PROST-TRANSLATIONAL MODIFICATION
Descriptor:ASPARTATE 1-DECARBOXYLASE, PANZ, THIOCYANATE ION, ...
Authors:Monteiro, D.C.F., Patel, V., Bartlett, C.P., Grant, T.D., Nozaki, S., Gowdy, J.A., Snell, E.H., Niki, H., Pearson, A.R., Webb, M.E.
Deposit date:2014-03-02
Release date:2015-03-25
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structure of the Pand/Panz Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A.
Chem.Biol., 22, 2015
4CS0
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DIRECT VISUALISATION OF STRAIN-INDUCED PROTEIN POST-TRANSLATIONAL MODIFICATION
Descriptor:ASPARTATE 1-DECARBOXYLASE, PANZ, THIOCYANATE ION, ...
Authors:Monteiro, D.C.F., Patel, V., Bartlett, C.P., Grant, T.D., Nozaki, S., Gowdy, J.A., Snell, E.H., Niki, H., Pearson, A.R., Webb, M.E.
Deposit date:2014-03-02
Release date:2015-03-25
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of the Pand/Panz Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A.
Chem.Biol., 22, 2015