1A58 | | CYCLOPHILIN FROM BRUGIA MALAYI | | Descriptor: | CYCLOPHILIN | | Authors: | Taylor, P., Page, A.P., Kontopidis, G., Husi, H., Walkinshaw, M.D. | | Deposit date: | 1998-02-20 | | Release date: | 1998-05-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The X-ray structure of a divergent cyclophilin from the nematode parasite Brugia malayi.
FEBS Lett., 425, 1998
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1IHG | | BOVINE CYCLOPHILIN 40, MONOCLINIC FORM | | Descriptor: | Cyclophilin 40, GLYCEROL | | Authors: | Taylor, P., Dornan, J., Carrello, A., Minchin, R.F., Ratajczak, T., Walkinshaw, M.D. | | Deposit date: | 2001-04-19 | | Release date: | 2001-05-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Two structures of cyclophilin 40: folding and fidelity in the TPR domains.
Structure, 9, 2001
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1IIP | | BOVINE CYCLOPHILIN 40, TETRAGONAL FORM | | Descriptor: | Cyclophilin 40, GLYCEROL | | Authors: | Taylor, P., Dornan, J., Carrello, A., Minchin, R.F., Ratajczak, T., Walkinshaw, M.D. | | Deposit date: | 2001-04-24 | | Release date: | 2001-05-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Two structures of cyclophilin 40: folding and fidelity in the TPR domains.
Structure, 9, 2001
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1IJ9 | | HIGHLY HYDRATED HUMAN VCAM-1 FRAGMENT | | Descriptor: | VASCULAR CELL ADHESION PROTEIN 1 | | Authors: | Taylor, P., Bilsland, M., Walkinshaw, M.D. | | Deposit date: | 2001-04-25 | | Release date: | 2001-05-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A new conformation of the integrin-binding fragment of human VCAM-1 crystallizes in a highly hydrated packing arrangement.
Acta Crystallogr.,Sect.D, 57, 2001
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1QJD | | FLAVOCYTOCHROME C3 FROM SHEWANELLA FRIGIDIMARINA | | Descriptor: | FLAVOCYTOCHROME C3, HEME C, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Taylor, P., Pealing, S.L., Reid, G.A., Chapman, S.K., Walkinshaw, M.D. | | Deposit date: | 1999-06-23 | | Release date: | 1999-11-21 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and Mechanistic Mapping of a Unique Fumarate Reductase
Nat.Struct.Biol., 6, 1999
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4CUD | | HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT FUCOSYLATED AT T466 | | Descriptor: | NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, ALPHA-L-FUCOSE, CALCIUM ION | | Authors: | Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A. | | Deposit date: | 2014-03-18 | | Release date: | 2014-05-21 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CUE | | HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466V | | Descriptor: | NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION | | Authors: | Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A. | | Deposit date: | 2014-03-18 | | Release date: | 2014-05-21 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CUF | | HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466S | | Descriptor: | NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION, 1,2-ETHANEDIOL | | Authors: | Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A. | | Deposit date: | 2014-03-18 | | Release date: | 2014-05-14 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4D0E | | HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT GLCNAC-FUCOSE DISACCHARIDE MODIFIED AT T466 | | Descriptor: | NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ... | | Authors: | Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A. | | Deposit date: | 2014-04-25 | | Release date: | 2014-05-21 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4D0F | | HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466A | | Descriptor: | NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION, 1,2-ETHANEDIOL | | Authors: | Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A. | | Deposit date: | 2014-04-25 | | Release date: | 2014-05-21 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1E8K | | CYCLOPHILIN 3 COMPLEXED WITH DIPEPTIDE ALA-PRO | | Descriptor: | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 3, ALANINE, PROLINE | | Authors: | Wu, S.Y., Dornan, J., Kontopidis, G., Taylor, P., Walkinshaw, M.D. | | Deposit date: | 2000-09-25 | | Release date: | 2001-09-20 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The First Direct Determination of a Ligand Binding Constant in Protein Crystals
Angew.Chem.Int.Ed.Engl., 40, 2001
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2WQZ | | CRYSTAL STRUCTURE OF SYNAPTIC PROTEIN NEUROLIGIN-4 IN COMPLEX WITH NEUREXIN-BETA 1: ALTERNATIVE REFINEMENT | | Descriptor: | NEUROLIGIN 4, X-LINKED, NEUREXIN-1-BETA, ... | | Authors: | Fabrichny, I.P., Leone, P., Sulzenbacher, G., Comoletti, D., Miller, M.T., Taylor, P., Bourne, Y., Marchot, P. | | Deposit date: | 2009-08-28 | | Release date: | 2009-09-08 | | Last modified: | 2016-08-24 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Structural Analysis of the Synaptic Protein Neuroligin and its Beta-Neurexin Complex: Determinants for Folding and Cell Adhesion.
Neuron, 56, 2007
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2XB6 | | REVISITED CRYSTAL STRUCTURE OF NEUREXIN1BETA-NEUROLIGIN4 COMPLEX | | Descriptor: | NEUROLIGIN-4, X-LINKED, NEUREXIN-1-BETA, ... | | Authors: | Leone, P., Comoletti, D., Ferracci, G., Conrod, S., Garcia, S.U., Taylor, P., Bourne, Y., Marchot, P. | | Deposit date: | 2010-04-07 | | Release date: | 2010-06-23 | | Last modified: | 2019-04-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Insights Into the Exquisite Selectivity of Neurexin-Neuroligin Synaptic Interactions
Embo J., 29, 2010
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3BE8 | | CRYSTAL STRUCTURE OF THE SYNAPTIC PROTEIN NEUROLIGIN 4 | | Descriptor: | Neuroligin-4, X-linked, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Fabrichny, I.P., Leone, P., Sulzenbacher, G., Comoletti, D., Miller, M.T., Taylor, P., Bourne, Y., Marchot, P. | | Deposit date: | 2007-11-16 | | Release date: | 2008-01-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Analysis of the Synaptic Protein Neuroligin and Its beta-Neurexin Complex: Determinants for Folding and Cell Adhesion
Neuron, 56, 2007
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1J3I | | WILD-TYPE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH WR99210, NADPH, AND DUMP | | Descriptor: | Bifunctional dihydrofolate reductase-thymidylate synthase, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y. | | Deposit date: | 2003-02-03 | | Release date: | 2003-05-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
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1J3J | | DOUBLE MUTANT (C59R+S108N) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH PYRIMETHAMINE, NADPH, AND DUMP | | Descriptor: | Bifunctional dihydrofolate reductase-thymidylate synthase, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y. | | Deposit date: | 2003-02-03 | | Release date: | 2003-05-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
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1J3K | | QUADRUPLE MUTANT (N51I+C59R+S108N+I164L) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH WR99210, NADPH, AND DUMP | | Descriptor: | Bifunctional dihydrofolate reductase-thymidylate synthase, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y. | | Deposit date: | 2003-02-03 | | Release date: | 2003-05-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
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1D6O | | NATIVE FKBP | | Descriptor: | PROTEIN (FK506-BINDING PROTEIN), AMMONIUM ION, SULFATE ION | | Authors: | Burkhard, P., Taylor, P., Walkinshaw, M.D. | | Deposit date: | 1999-10-15 | | Release date: | 1999-10-21 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
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1D7H | | FKBP COMPLEXED WITH DMSO | | Descriptor: | PROTEIN (FK506-BINDING PROTEIN), AMMONIUM ION, SULFATE ION, ... | | Authors: | Burkhard, P., Taylor, P., Walkinshaw, M.D. | | Deposit date: | 1999-10-18 | | Release date: | 1999-10-21 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
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1D7I | | FKBP COMPLEXED WITH METHYL METHYLSULFINYLMETHYL SULFIDE (DSS) | | Descriptor: | PROTEIN (FK506-BINDING PROTEIN), AMMONIUM ION, SULFATE ION, ... | | Authors: | Burkhard, P., Taylor, P., Walkinshaw, M.D. | | Deposit date: | 1999-10-18 | | Release date: | 1999-10-21 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
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1D7J | | FKBP COMPLEXED WITH 4-HYDROXY-2-BUTANONE | | Descriptor: | PROTEIN (FK506-BINDING PROTEIN), AMMONIUM ION, SULFATE ION, ... | | Authors: | Burkhard, P., Taylor, P., Walkinshaw, M.D. | | Deposit date: | 1999-10-18 | | Release date: | 1999-10-21 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
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1J06 | | CRYSTAL STRUCTURE OF MOUSE ACETYLCHOLINESTERASE IN THE APO FORM | | Descriptor: | acetylcholinesterase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ... | | Authors: | Bourne, Y., Taylor, P., Radic, Z., Marchot, P. | | Deposit date: | 2002-11-07 | | Release date: | 2003-02-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
EMBO J., 22, 2003
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1J07 | | CRYSTAL STRUCTURE OF THE MOUSE ACETYLCHOLINESTERASE-DECIDIUM COMPLEX | | Descriptor: | acetylcholinesterase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ... | | Authors: | Bourne, Y., Taylor, P., Radic, Z., Marchot, P. | | Deposit date: | 2002-11-07 | | Release date: | 2003-02-04 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
EMBO J., 22, 2003
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1KU6 | | FASCICULIN 2-MOUSE ACETYLCHOLINESTERASE COMPLEX | | Descriptor: | ACETYLCHOLINESTERASE, FASCICULIN 2, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Bourne, Y., Burmeister, W., Taylor, P., Marchot, P. | | Deposit date: | 2002-01-21 | | Release date: | 2003-12-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.
EMBO J., 22, 2003
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1MAA | | MOUSE ACETYLCHOLINESTERASE CATALYTIC DOMAIN, GLYCOSYLATED PROTEIN | | Descriptor: | ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, DECAMETHONIUM ION, ... | | Authors: | Bourne, Y., Taylor, P., Bougis, P.E., Marchot, P. | | Deposit date: | 1998-11-04 | | Release date: | 1999-04-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly.
J.Biol.Chem., 274, 1999
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