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1A58
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CYCLOPHILIN FROM BRUGIA MALAYI
Descriptor:CYCLOPHILIN
Authors:Taylor, P., Page, A.P., Kontopidis, G., Husi, H., Walkinshaw, M.D.
Deposit date:1998-02-20
Release date:1998-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The X-ray structure of a divergent cyclophilin from the nematode parasite Brugia malayi.
FEBS Lett., 425, 1998
1IHG
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BOVINE CYCLOPHILIN 40, MONOCLINIC FORM
Descriptor:Cyclophilin 40, GLYCEROL
Authors:Taylor, P., Dornan, J., Carrello, A., Minchin, R.F., Ratajczak, T., Walkinshaw, M.D.
Deposit date:2001-04-19
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two structures of cyclophilin 40: folding and fidelity in the TPR domains.
Structure, 9, 2001
1IIP
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BOVINE CYCLOPHILIN 40, TETRAGONAL FORM
Descriptor:Cyclophilin 40, GLYCEROL
Authors:Taylor, P., Dornan, J., Carrello, A., Minchin, R.F., Ratajczak, T., Walkinshaw, M.D.
Deposit date:2001-04-24
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two structures of cyclophilin 40: folding and fidelity in the TPR domains.
Structure, 9, 2001
1IJ9
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HIGHLY HYDRATED HUMAN VCAM-1 FRAGMENT
Descriptor:VASCULAR CELL ADHESION PROTEIN 1
Authors:Taylor, P., Bilsland, M., Walkinshaw, M.D.
Deposit date:2001-04-25
Release date:2001-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A new conformation of the integrin-binding fragment of human VCAM-1 crystallizes in a highly hydrated packing arrangement.
Acta Crystallogr.,Sect.D, 57, 2001
1QJD
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FLAVOCYTOCHROME C3 FROM SHEWANELLA FRIGIDIMARINA
Descriptor:FLAVOCYTOCHROME C3, HEME C, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Taylor, P., Pealing, S.L., Reid, G.A., Chapman, S.K., Walkinshaw, M.D.
Deposit date:1999-06-23
Release date:1999-11-21
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Mechanistic Mapping of a Unique Fumarate Reductase
Nat.Struct.Biol., 6, 1999
4CUD
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HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT FUCOSYLATED AT T466
Descriptor:NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, ALPHA-L-FUCOSE, CALCIUM ION
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A.
Deposit date:2014-03-18
Release date:2014-05-21
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CUE
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HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466V
Descriptor:NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A.
Deposit date:2014-03-18
Release date:2014-05-21
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CUF
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HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466S
Descriptor:NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION, 1,2-ETHANEDIOL
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A.
Deposit date:2014-03-18
Release date:2014-05-14
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4D0E
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HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT GLCNAC-FUCOSE DISACCHARIDE MODIFIED AT T466
Descriptor:NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A.
Deposit date:2014-04-25
Release date:2014-05-21
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4D0F
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HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466A
Descriptor:NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION, 1,2-ETHANEDIOL
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S.M., Haltiwanger, R.S., Handford, P.A.
Deposit date:2014-04-25
Release date:2014-05-21
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
1E8K
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CYCLOPHILIN 3 COMPLEXED WITH DIPEPTIDE ALA-PRO
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 3, ALANINE, PROLINE
Authors:Wu, S.Y., Dornan, J., Kontopidis, G., Taylor, P., Walkinshaw, M.D.
Deposit date:2000-09-25
Release date:2001-09-20
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The First Direct Determination of a Ligand Binding Constant in Protein Crystals
Angew.Chem.Int.Ed.Engl., 40, 2001
1J3I
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WILD-TYPE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH WR99210, NADPH, AND DUMP
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y.
Deposit date:2003-02-03
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
1J3J
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DOUBLE MUTANT (C59R+S108N) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH PYRIMETHAMINE, NADPH, AND DUMP
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y.
Deposit date:2003-02-03
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
1J3K
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QUADRUPLE MUTANT (N51I+C59R+S108N+I164L) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH WR99210, NADPH, AND DUMP
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y.
Deposit date:2003-02-03
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
2WQZ
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CRYSTAL STRUCTURE OF SYNAPTIC PROTEIN NEUROLIGIN-4 IN COMPLEX WITH NEUREXIN-BETA 1: ALTERNATIVE REFINEMENT
Descriptor:NEUROLIGIN 4, X-LINKED, NEUREXIN-1-BETA, ...
Authors:Fabrichny, I.P., Leone, P., Sulzenbacher, G., Comoletti, D., Miller, M.T., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2009-08-28
Release date:2009-09-08
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Analysis of the Synaptic Protein Neuroligin and its Beta-Neurexin Complex: Determinants for Folding and Cell Adhesion.
Neuron, 56, 2007
2XB6
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REVISITED CRYSTAL STRUCTURE OF NEUREXIN1BETA-NEUROLIGIN4 COMPLEX
Descriptor:NEUROLIGIN-4, X-LINKED, NEUREXIN-1-BETA, ...
Authors:Leone, P., Comoletti, D., Ferracci, G., Conrod, S., Garcia, S.U., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2010-04-07
Release date:2010-06-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights Into the Exquisite Selectivity of Neurexin-Neuroligin Synaptic Interactions
Embo J., 29, 2010
3BE8
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CRYSTAL STRUCTURE OF THE SYNAPTIC PROTEIN NEUROLIGIN 4
Descriptor:Neuroligin-4, X-linked, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Fabrichny, I.P., Leone, P., Sulzenbacher, G., Comoletti, D., Miller, M.T., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2007-11-16
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of the Synaptic Protein Neuroligin and Its beta-Neurexin Complex: Determinants for Folding and Cell Adhesion
Neuron, 56, 2007
1D6O
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NATIVE FKBP
Descriptor:PROTEIN (FK506-BINDING PROTEIN), AMMONIUM ION, SULFATE ION
Authors:Burkhard, P., Taylor, P., Walkinshaw, M.D.
Deposit date:1999-10-15
Release date:1999-10-21
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
1D7H
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FKBP COMPLEXED WITH DMSO
Descriptor:PROTEIN (FK506-BINDING PROTEIN), AMMONIUM ION, SULFATE ION, ...
Authors:Burkhard, P., Taylor, P., Walkinshaw, M.D.
Deposit date:1999-10-18
Release date:1999-10-21
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
1D7I
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FKBP COMPLEXED WITH METHYL METHYLSULFINYLMETHYL SULFIDE (DSS)
Descriptor:PROTEIN (FK506-BINDING PROTEIN), AMMONIUM ION, SULFATE ION, ...
Authors:Burkhard, P., Taylor, P., Walkinshaw, M.D.
Deposit date:1999-10-18
Release date:1999-10-21
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
1D7J
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FKBP COMPLEXED WITH 4-HYDROXY-2-BUTANONE
Descriptor:PROTEIN (FK506-BINDING PROTEIN), AMMONIUM ION, SULFATE ION, ...
Authors:Burkhard, P., Taylor, P., Walkinshaw, M.D.
Deposit date:1999-10-18
Release date:1999-10-21
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
1J06
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CRYSTAL STRUCTURE OF MOUSE ACETYLCHOLINESTERASE IN THE APO FORM
Descriptor:acetylcholinesterase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Bourne, Y., Taylor, P., Radic, Z., Marchot, P.
Deposit date:2002-11-07
Release date:2003-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
EMBO J., 22, 2003
1J07
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CRYSTAL STRUCTURE OF THE MOUSE ACETYLCHOLINESTERASE-DECIDIUM COMPLEX
Descriptor:acetylcholinesterase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Bourne, Y., Taylor, P., Radic, Z., Marchot, P.
Deposit date:2002-11-07
Release date:2003-02-04
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
EMBO J., 22, 2003
1KU6
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FASCICULIN 2-MOUSE ACETYLCHOLINESTERASE COMPLEX
Descriptor:ACETYLCHOLINESTERASE, FASCICULIN 2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Bourne, Y., Burmeister, W., Taylor, P., Marchot, P.
Deposit date:2002-01-21
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.
EMBO J., 22, 2003
1MAA
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MOUSE ACETYLCHOLINESTERASE CATALYTIC DOMAIN, GLYCOSYLATED PROTEIN
Descriptor:ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, DECAMETHONIUM ION, ...
Authors:Bourne, Y., Taylor, P., Bougis, P.E., Marchot, P.
Deposit date:1998-11-04
Release date:1999-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly.
J.Biol.Chem., 274, 1999