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1MB1
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BU of 1mb1 by Molmil
MBP1 FROM SACCHAROMYCES CEREVISIAE
Descriptor: MLU1-BOX BINDING PROTEIN
Authors:Taylor, I.A, Smerdon, S.J.
Deposit date:1997-07-23
Release date:1998-07-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The X-ray structure of the DNA-binding domain from the Saccharomyces cerevisiae cell-cycle transcription factor Mbp1 at 2.1 A resolution.
J.Mol.Biol., 272, 1997
5M1H
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BU of 5m1h by Molmil
Structure of a Spumaretrovirus Gag central domain reveals an ancient retroviral capsid
Descriptor: Gag protein
Authors:Taylor, I.A, Nicastro, G, Ball, N.
Deposit date:2016-10-07
Release date:2016-10-26
Last modified:2016-11-23
Method:SOLUTION NMR
Cite:Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.
Plos Pathog., 12, 2016
2XFV
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BU of 2xfv by Molmil
Structure of the amino-terminal domain from the cell-cycle regulator Swi6
Descriptor: ACETATE ION, CACODYLATE ION, CALCIUM ION, ...
Authors:Smerdon, S.J, Goldstone, D.C, Taylor, I.A.
Deposit date:2010-05-27
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Amino-Terminal Domain from the Cell-Cycle Regulator Swi6S
Proteins, 78, 2010
4JMR
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BU of 4jmr by Molmil
A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid
Descriptor: Env protein, Gag protein
Authors:Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J.
Deposit date:2013-03-14
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
4JNH
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BU of 4jnh by Molmil
A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid
Descriptor: Gag polyprotein
Authors:Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J.
Deposit date:2013-03-15
Release date:2013-05-29
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
7ZUD
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BU of 7zud by Molmil
Crystal structure of HIV-1 capsid IP6-CPSF6 complex
Descriptor: Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE
Authors:Nicastro, G, Taylor, I.A.
Deposit date:2022-05-12
Release date:2022-07-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1.
J.Mol.Biol., 434, 2022
5M1G
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BU of 5m1g by Molmil
Structure of a Spumaretrovirus Gag central domain reveals an ancient retroviral capsid
Descriptor: Gag protein
Authors:Nicastro, G, Ball, N, Taylor, I.A.
Deposit date:2016-10-07
Release date:2016-10-26
Last modified:2019-10-30
Method:SOLUTION NMR
Cite:Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.
Plos Pathog., 12, 2016
4TN3
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BU of 4tn3 by Molmil
Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha
Descriptor: TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera, ZINC ION
Authors:Kirkpatrick, J.J, Stoye, J.P, Taylor, I.A, Goldstone, D.C.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1989 Å)
Cite:Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.
Proc.Natl.Acad.Sci.USA, 111, 2014
6ES4
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BU of 6es4 by Molmil
A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ...
Authors:Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A.
Deposit date:2017-10-19
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.
Nat Commun, 9, 2018
6XU1
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BU of 6xu1 by Molmil
Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ...
Authors:Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A.
Deposit date:2020-01-17
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
6YOM
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BU of 6yom by Molmil
Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dATP, dCMPNPP, Mn and Mg
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A.
Deposit date:2020-04-14
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
7A5Y
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BU of 7a5y by Molmil
Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with Rp-dGTP-alphaS (T8T) and Mg
Descriptor: 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ...
Authors:Morris, E.R, Kunzelmann, S, Caswell, S.J, Purkiss, A, Taylor, I.A.
Deposit date:2020-08-24
Release date:2021-05-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of R p - and S p -dNTP alpha S Diastereomers.
Biochemistry, 60, 2021
6ZUE
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BU of 6zue by Molmil
Crystal structure of human DDB1 bound to human DCAF1 (amino acid residues 1046-1396)
Descriptor: DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2020-07-22
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.094 Å)
Cite:Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.
Plos Pathog., 17, 2021
7NLI
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BU of 7nli by Molmil
S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG2 variant
Descriptor: Ty1 Gag p22
Authors:Cottee, M.A, Letham, S.C, Taylor, I.A.
Deposit date:2021-02-22
Release date:2021-10-06
Method:X-RAY DIFFRACTION (3.119 Å)
Cite:Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
7NLG
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BU of 7nlg by Molmil
S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG2 variant A273V mutant
Descriptor: Ty1 Gag p22
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2021-02-22
Release date:2021-10-06
Method:X-RAY DIFFRACTION (3.528 Å)
Cite:Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
7NLH
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BU of 7nlh by Molmil
S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG1 variant
Descriptor: Ty1 Gag p22
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2021-02-22
Release date:2021-10-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
4UX5
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BU of 4ux5 by Molmil
Structure of DNA complex of PCG2
Descriptor: 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3', TRANSCRIPTION FACTOR MBP1
Authors:Liu, J, Huang, J, Zhao, Y, Liu, H, Wang, D, Yang, J, Zhao, W, Taylor, I.A, Peng, Y.
Deposit date:2014-08-19
Release date:2015-01-14
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains.
Nucleic Acids Res., 43, 2015
2XGV
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BU of 2xgv by Molmil
Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK)
Descriptor: PSIV CAPSID N-TERMINAL DOMAIN
Authors:Goldstone, D.C, Robertson, L.E, Haire, L.F, Stoye, J.P, Taylor, I.A.
Deposit date:2010-06-07
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface.
Cell Host Microbe, 8, 2010
2XGU
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BU of 2xgu by Molmil
Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK)
Descriptor: ACETATE ION, RELIK CAPSID N-TERMINAL DOMAIN
Authors:Goldstone, D.C, Taylor, I.A, Robertson, L.E, Haire, L.F, Stoye, J.P.
Deposit date:2010-06-07
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface.
Cell Host Microbe, 8, 2010
2XGY
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BU of 2xgy by Molmil
Complex of Rabbit Endogenous Lentivirus (RELIK)Capsid with Cyclophilin A
Descriptor: GLYCEROL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, RELIK CAPSID N-TERMINAL DOMAIN
Authors:Goldstone, D.C, Robertson, L.E, Haire, L.F, Stoye, J.P, Taylor, I.A.
Deposit date:2010-06-08
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface.
Cell Host Microbe, 8, 2010
3U1N
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BU of 3u1n by Molmil
Structure of the catalytic core of human SAMHD1
Descriptor: PHOSPHATE ION, SAM domain and HD domain-containing protein 1, ZINC ION
Authors:Goldstone, D.C, Ennis-Adeniran, V, Walker, P.A, Haire, L.F, Webb, M, Taylor, I.A.
Deposit date:2011-09-30
Release date:2011-11-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
Nature, 480, 2011
2V4X
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BU of 2v4x by Molmil
Crystal Structure of Jaagsiekte Sheep Retrovirus Capsid N-terminal domain
Descriptor: CAPSID PROTEIN P27
Authors:Mortuza, G.B, Goldstone, D.C, Pashley, C, Haire, L.F, Palmarini, M, Taylor, W.R, Stoye, J.P, Taylor, I.A.
Deposit date:2008-09-30
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus.
J.Mol.Biol., 386, 2009
2Y4Z
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BU of 2y4z by Molmil
Structure of the amino-terminal capsid restriction escape mutation N- MLV L10W
Descriptor: CAPSID PROTEIN P30, GLYCEROL
Authors:Goldstone, D.C, Holden-Dye, K, Ohkura, S, Stoye, J.P, Taylor, I.A.
Deposit date:2011-01-11
Release date:2011-11-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Novel Escape Mutants Suggest an Extensive Trim5Alpha Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein.
Plos Pathog., 7, 2011
6S7X
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BU of 6s7x by Molmil
dARC1 capsid domain dimer, orthorhombic form at 1.7 Angstrom
Descriptor: Activity-regulated cytoskeleton associated protein 1, CHLORIDE ION, SODIUM ION
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2019-07-07
Release date:2020-01-15
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure ofDrosophila melanogasterARC1 reveals a repurposed molecule with characteristics of retroviral Gag.
Sci Adv, 6, 2020
6S7Y
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BU of 6s7y by Molmil
dARC1 capsid domain dimer, hexagonal form at 2.3 Angstrom
Descriptor: Activity-regulated cytoskeleton associated protein 1
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2019-07-07
Release date:2020-01-15
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure ofDrosophila melanogasterARC1 reveals a repurposed molecule with characteristics of retroviral Gag.
Sci Adv, 6, 2020

 

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