5Y28 | |
5Y2D | | CRYSTAL STRUCTURE OF H. PYLORI HTRA | | Descriptor: | Periplasmic serine endoprotease DegP-like, UNK-UNK-UNK, UNK-UNK-UNK-UNK-UNK, ... | | Authors: | Zhang, Z., Huang, Q., Tao, X. | | Deposit date: | 2017-07-25 | | Release date: | 2018-08-15 | | Method: | X-RAY DIFFRACTION (3.700099 Å) | | Cite: | Crystal structure of H. pylori HtrA
To Be Published
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5TJI | | CA2+ BOUND APLYSIA SLO1 | | Descriptor: | High conductance calcium-activated potassium channel, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate | | Authors: | MacKinnon, R., Tao, X., Hite, R.K. | | Deposit date: | 2016-10-04 | | Release date: | 2016-12-28 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis for gating the high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
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5TJ6 | | CA2+ BOUND APLYSIA SLO1 | | Descriptor: | High conductance calcium-activated potassium channel, POTASSIUM ION, MAGNESIUM ION, ... | | Authors: | MacKinnon, R., Tao, X., Hite, R.K. | | Deposit date: | 2016-10-03 | | Release date: | 2016-12-14 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of the open high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
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5BXJ | | COMPLEX OF THE FK1 DOMAIN MUTANT A19T OF FKBP51 WITH 4-NITROPHENOL | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL | | Authors: | Wu, D., Tao, X., Chen, Z., Han, J., Jia, W., Li, X., Wang, Z., He, Y.X. | | Deposit date: | 2015-06-09 | | Release date: | 2016-05-25 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells
J. Hazard. Mater., 307, 2016
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4IJS | |
4DXW | | CRYSTAL STRUCTURE OF NAVRH, A VOLTAGE-GATED SODIUM CHANNEL | | Descriptor: | Ion transport protein, B-NONYLGLUCOSIDE, CALCIUM ION, ... | | Authors: | Zhang, X., Ren, W.L., Yan, C.Y., Wang, J.W., Yan, N. | | Deposit date: | 2012-02-28 | | Release date: | 2012-05-23 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (3.052 Å) | | Cite: | Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
Nature, 486, 2012
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3SPC | | INWARD RECTIFIER POTASSIUM CHANNEL KIR2.2 IN COMPLEX WITH DIOCTANOYLGLYCEROL PYROPHOSPHATE (DGPP) | | Descriptor: | Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, (2R)-3-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}propane-1,2-diyl dioctanoate | | Authors: | Hansen, S.B., Tao, X., MacKinnon, R. | | Deposit date: | 2011-07-01 | | Release date: | 2011-08-24 | | Last modified: | 2011-09-21 | | Method: | X-RAY DIFFRACTION (2.454 Å) | | Cite: | Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
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3SPG | | INWARD RECTIFIER POTASSIUM CHANNEL KIR2.2 R186A MUTANT IN COMPLEX WITH PIP2 | | Descriptor: | Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Hansen, S.B., Tao, X., MacKinnon, R. | | Deposit date: | 2011-07-01 | | Release date: | 2011-08-24 | | Last modified: | 2011-09-21 | | Method: | X-RAY DIFFRACTION (2.613 Å) | | Cite: | Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
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3SPH | | INWARD RECTIFIER POTASSIUM CHANNEL KIR2.2 I223L MUTANT IN COMPLEX WITH PIP2 | | Descriptor: | Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Hansen, S.B., Tao, X., MacKinnon, R. | | Deposit date: | 2011-07-01 | | Release date: | 2011-08-24 | | Last modified: | 2011-09-21 | | Method: | X-RAY DIFFRACTION (3.003 Å) | | Cite: | Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
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3SPI | | INWARD RECTIFIER POTASSIUM CHANNEL KIR2.2 IN COMPLEX WITH PIP2 | | Descriptor: | Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Hansen, S.B., Tao, X., MacKinnon, R. | | Deposit date: | 2011-07-01 | | Release date: | 2011-08-24 | | Last modified: | 2011-09-21 | | Method: | X-RAY DIFFRACTION (3.307 Å) | | Cite: | Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
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3SPJ | |
3LUT | | A STRUCTURAL MODEL FOR THE FULL-LENGTH SHAKER POTASSIUM CHANNEL KV1.2 | | Descriptor: | Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Chen, X., Ni, F., Wang, Q., Ma, J. | | Deposit date: | 2010-02-18 | | Release date: | 2010-06-23 | | Last modified: | 2011-10-26 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3LNM | | F233W MUTANT OF THE KV2.1 PADDLE-KV1.2 CHIMERA CHANNEL | | Descriptor: | Voltage-gated potassium channel subunit beta-2, F233W mutant of the Kv2.1 paddle-Kv1.2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Tao, X., Lee, A., Limapichat, W., Dougherty, D.A., MacKinnon, R. | | Deposit date: | 2010-02-02 | | Release date: | 2010-04-14 | | Last modified: | 2017-08-02 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A gating charge transfer center in voltage sensors.
Science, 328, 2010
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3JYC | |
2R9R | | SHAKER FAMILY VOLTAGE DEPENDENT POTASSIUM CHANNEL (KV1.2-KV2.1 PADDLE CHIMERA CHANNEL) IN ASSOCIATION WITH BETA SUBUNIT | | Descriptor: | Voltage-gated potassium channel subunit beta-2, Paddle chimera voltage gated potassium channel Kv1.2-Kv2.1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Long, S.B., Tao, X., Campbell, E.B., Mackinnon, R. | | Deposit date: | 2007-09-13 | | Release date: | 2007-11-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment.
Nature, 450, 2007
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2JS7 | | SOLUTION NMR STRUCTURE OF HUMAN MYELOID DIFFERENTIATION PRIMARY RESPONSE (MYD88). NORTHEAST STRUCTURAL GENOMICS TARGET HR2869A | | Descriptor: | Myeloid differentiation primary response protein MyD88 | | Authors: | Rossi, P., Ramelot, T.A., Tao, X., Ciano, M., Ho, C., Ma, L.-C., Xiao, R., Acton, T.B., Kennedy, M.A., Tong, L., Montelione, G.T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-06-29 | | Release date: | 2007-10-23 | | Last modified: | 2018-01-24 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Human Myeloid Differentiation Primary Response (MyD88).
To be Published
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2OUC | |
2OUD | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN MKP5 | | Descriptor: | Dual specificity protein phosphatase 10, CHLORIDE ION | | Authors: | Tao, X., Tong, L. | | Deposit date: | 2007-02-10 | | Release date: | 2007-08-07 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5.
Protein Sci., 16, 2007
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2GVL | | CRYSTAL STRUCTURE OF MURINE NMPRTASE | | Descriptor: | Nicotinamide phosphoribosyltransferase | | Authors: | Khan, J.A., Tao, X., Tong, L. | | Deposit date: | 2006-05-02 | | Release date: | 2006-07-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13, 2006
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2GVG | | CRYSTAL STRUCTURE OF HUMAN NMPRTASE AND ITS COMPLEX WITH NMN | | Descriptor: | Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | | Authors: | Khan, J.A., Tao, X., Tong, L. | | Deposit date: | 2006-05-02 | | Release date: | 2006-06-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13, 2006
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2GVJ | | CRYSTAL STRUCTURE OF HUMAN NMPRTASE IN COMPLEX WITH FK866 | | Descriptor: | Nicotinamide phosphoribosyltransferase, (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide | | Authors: | Khan, J.A., Tao, X., Tong, L. | | Deposit date: | 2006-05-02 | | Release date: | 2006-06-20 | | Last modified: | 2016-11-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13, 2006
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1PJ2 | | CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, COFACTOR NADH, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE | | Descriptor: | NAD-dependent malic enzyme, mitochondrial, (2S)-2-hydroxybutanedioic acid, ... | | Authors: | Tao, X., Yang, Z., Tong, L. | | Deposit date: | 2003-05-30 | | Release date: | 2003-11-11 | | Last modified: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
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1PJ3 | | CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE PYRUVATE, COFACTOR NAD+, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | | Descriptor: | NAD-dependent malic enzyme, mitochondrial, MANGANESE (II) ION, ... | | Authors: | Tao, X., Yang, Z., Tong, L. | | Deposit date: | 2003-05-30 | | Release date: | 2003-11-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
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1PJ4 | | CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, ATP, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | | Descriptor: | NAD-dependent malic enzyme, mitochondrial, D-MALATE, ... | | Authors: | Tao, X., Yang, Z., Tong, L. | | Deposit date: | 2003-05-31 | | Release date: | 2003-09-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
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