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2DHR
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WHOLE CYTOSOLIC REGION OF ATP-DEPENDENT METALLOPROTEASE FTSH (G399L)
Descriptor:FtsH, ADENOSINE-5'-DIPHOSPHATE
Authors:Suno, R., Niwa, H., Tsuchiya, D., Zhang, X., Yoshida, M., Morikawa, K.
Deposit date:2006-03-24
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH
Mol.Cell, 22, 2006
2DI4
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CRYSTAL STRUCTURE OF THE FTSH PROTEASE DOMAIN
Descriptor:Cell division protein ftsH homolog, MERCURY (II) ION
Authors:Suno, R., Niwa, H., Tsuchiya, D., Zhang, X., Yoshida, M., Morikawa, K.
Deposit date:2006-03-28
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH
Mol.Cell, 22, 2006
4EIW
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WHOLE CYTOSOLIC REGION OF ATP-DEPENDENT METALLOPROTEASE FTSH (G399L)
Descriptor:ATP-dependent zinc metalloprotease FtsH, ADENOSINE-5'-DIPHOSPHATE
Authors:Suno, R., Niwa, H., Tsuchiya, D., Yoshida, M., Morikawa, K.
Deposit date:2012-04-06
Release date:2012-06-06
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structure of the whole cytosolic region of ATP-dependent protease FtsH
Mol.Cell, 22, 2006
5WQC
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CRYSTAL STRUCTURE OF HUMAN OREXIN 2 RECEPTOR BOUND TO THE SELECTIVE ANTAGONIST EMPA DETERMINED BY THE SYNCHROTRON LIGHT SOURCE AT SPRING-8.
Descriptor:Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, ...
Authors:Suno, R., Hirata, K., Yamashita, K., Tsujimoto, H., Sasanuma, M., Horita, S., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T.
Deposit date:2016-11-25
Release date:2017-11-29
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA
Structure, 26, 2018
5WS3
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CRYSTAL STRUCTURES OF HUMAN OREXIN 2 RECEPTOR BOUND TO THE SELECTIVE ANTAGONIST EMPA DETERMINED BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY AT SACLA
Descriptor:Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, ...
Authors:Suno, R., Kimura, K., Nakane, T., Yamashita, K., Wang, J., Fujiwara, T., Yamanaka, Y., Im, D., Tsujimoto, H., Sasanuma, M., Horita, S., Hirokawa, T., Nango, E., Tono, K., Kameshima, T., Hatsui, T., Joti, Y., Yabashi, M., Shimamoto, K., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T.
Deposit date:2016-12-05
Release date:2017-12-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA.
Structure, 26, 2018
5YC8
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CRYSTAL STRUCTURE OF RATIONALLY THERMOSTABILIZED M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND WITH NMS (HG-DERIVATIVE)
Descriptor:Muscarinic acetylcholine receptor M2,Redesigned apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-methyl scopolamine, MERCURY (II) ION
Authors:Suno, R., Maeda, S., Yasuda, S., Yamashita, K., Hirata, K., Horita, S., Tawaramoto, M.S., Tsujimoto, H., Murata, T., Kinoshita, M., Yamamoto, M., Kobilka, B.K., Iwata, S., Kobayashi, T.
Deposit date:2017-09-06
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor
Nat. Chem. Biol., 14, 2018
5ZK3
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CRYSTAL STRUCTURE OF RATIONALLY THERMOSTABILIZED M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND WITH QNB
Descriptor:Muscarinic acetylcholine receptor M2,Apo-cytochrome b562,Muscarinic acetylcholine receptor M2, (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate
Authors:Suno, R., Maeda, S., Yasuda, S., Yamashita, K., Hirata, K., Horita, S., Tawaramoto, M.S., Tsujimoto, H., Murata, T., Kinoshita, M., Yamamoto, M., Kobilka, B.K., Iwata, S., Kobayashi, T.
Deposit date:2018-03-23
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor
Nat. Chem. Biol., 14, 2018
5ZK8
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CRYSTAL STRUCTURE OF M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND WITH NMS
Descriptor:Muscarinic acetylcholine receptor M2,Redesigned apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-methyl scopolamine
Authors:Suno, R., Maeda, S., Yasuda, S., Yamashita, K., Hirata, K., Horita, S., Tawaramoto, M.S., Tsujimoto, H., Murata, T., Kinoshita, M., Yamamoto, M., Kobilka, B.K., Iwata, S., Kobayashi, T.
Deposit date:2018-03-23
Release date:2018-11-21
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor
Nat. Chem. Biol., 14, 2018
5ZKB
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CRYSTAL STRUCTURE OF RATIONALLY THERMOSTABILIZED M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND WITH AF-DX 384
Descriptor:Muscarinic acetylcholine receptor M2,Apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-[2-[(2S)-2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxidanylidene-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
Authors:Suno, R., Maeda, S., Yasuda, S., Yamashita, K., Hirata, K., Horita, S., Tawaramoto, M.S., Tsujimoto, H., Murata, T., Kinoshita, M., Yamamoto, M., Kobilka, B.K., Iwata, S., Kobayashi, T.
Deposit date:2018-03-23
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor
Nat. Chem. Biol., 14, 2018
5ZKC
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CRYSTAL STRUCTURE OF RATIONALLY THERMOSTABILIZED M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND WITH NMS
Descriptor:Muscarinic acetylcholine receptor M2,Apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-methyl scopolamine
Authors:Suno, R., Maeda, S., Yasuda, S., Yamashita, K., Hirata, K., Horita, S., Tawaramoto, M.S., Tsujimoto, H., Murata, T., Kinoshita, M., Yamamoto, M., Kobilka, B.K., Iwata, S., Kobayashi, T.
Deposit date:2018-03-23
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor
Nat. Chem. Biol., 14, 2018
5YFI
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CRYSTAL STRUCTURE OF THE ANTI-HUMAN PROSTAGLANDIN E RECEPTOR EP4 ANTIBODY FAB FRAGMENT
Descriptor:Light chain of Fab fragment, Heavy chain of Fab fragment, ZINC ION
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-09-21
Release date:2018-12-05
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
5YHL
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CRYSTAL STRUCTURE OF THE HUMAN PROSTAGLANDIN E RECEPTOR EP4 IN COMPLEX WITH FAB AND AN ANTAGONIST BR-DERIVATIVE
Descriptor:Prostaglandin E2 receptor EP4 subtype, Heavy chain of Fab fragment, Light chain of Fab fragment, ...
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-09-28
Release date:2018-12-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
5YWY
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CRYSTAL STRUCTURE OF THE HUMAN PROSTAGLANDIN E RECEPTOR EP4 IN COMPLEX WITH FAB AND ONO-AE3-208
Descriptor:Prostaglandin E2 receptor EP4 subtype,Prostaglandin E2 receptor EP4 subtype, Heavy chain of Fab fragment, Light chain of Fab fragment, ...
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-11-30
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
6AK3
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CRYSTAL STRUCTURE OF THE HUMAN PROSTAGLANDIN E RECEPTOR EP3 BOUND TO PROSTAGLANDIN E2
Descriptor:Prostaglandin E2 receptor EP3 subtype,Soluble cytochrome b562, (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
Authors:Morimoto, K., Suno, R., Iwata, S., Kobayashi, T.
Deposit date:2018-08-29
Release date:2018-12-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the endogenous agonist-bound prostanoid receptor EP3.
Nat. Chem. Biol., 15, 2019