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1FBB
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CRYSTAL STRUCTURE OF NATIVE CONFORMATION OF BACTERIORHODOPSIN
Descriptor:BACTERIORHODOPSIN, RETINAL
Authors:Subramaniam, S., Henderson, R.
Deposit date:2000-07-15
Release date:2000-08-09
Last modified:2018-02-28
Method:ELECTRON CRYSTALLOGRAPHY (3.2 Å)
Cite:Molecular mechanism of vectorial proton translocation by bacteriorhodopsin.
Nature, 406, 2000
1FBK
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CRYSTAL STRUCTURE OF CYTOPLASMICALLY OPEN CONFORMATION OF BACTERIORHODOPSIN
Descriptor:BACTERIORHODOPSIN, RETINAL
Authors:Subramaniam, S., Henderson, R.
Deposit date:2000-07-15
Release date:2000-08-09
Last modified:2018-01-31
Method:ELECTRON CRYSTALLOGRAPHY (3.2 Å)
Cite:Molecular mechanism of vectorial proton translocation by bacteriorhodopsin.
Nature, 406, 2000
6CVM
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ATOMIC RESOLUTION CRYO-EM STRUCTURE OF BETA-GALACTOSIDASE
Descriptor:Beta-galactosidase, 2-phenylethyl 1-thio-beta-D-galactopyranoside, MAGNESIUM ION, ...
Authors:Subramaniam, S., Bartesaghi, A., Banerjee, S., Zhu, X., Milne, J.L.S.
Deposit date:2018-03-28
Release date:2018-05-30
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:Atomic Resolution Cryo-EM Structure of beta-Galactosidase.
Structure, 26, 2018
3J7H
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STRUCTURE OF BETA-GALACTOSIDASE AT 3.2-A RESOLUTION OBTAINED BY CRYO-ELECTRON MICROSCOPY
Descriptor:Beta-galactosidase, MAGNESIUM ION
Authors:Bartesaghi, A., Matthies, D., Banerjee, S., Merk, A., Subramaniam, S.
Deposit date:2014-06-30
Release date:2014-07-30
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of beta-galactosidase at 3.2- angstrom resolution obtained by cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 111, 2014
3JA7
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CRYO-EM STRUCTURE OF THE BACTERIOPHAGE T4 PORTAL PROTEIN ASSEMBLY AT NEAR-ATOMIC RESOLUTION
Descriptor:Portal protein gp20
Authors:Sun, L., Zhang, X., Gao, S., Rao, P.A., Padilla-Sanchez, V., Chen, Z., Sun, S., Xiang, Y., Subramaniam, S., Rao, V.B., Rossmann, M.G.
Deposit date:2015-04-21
Release date:2015-07-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution.
Nat Commun, 6, 2015
3JCZ
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STRUCTURE OF BOVINE GLUTAMATE DEHYDROGENASE IN THE UNLIGANDED STATE
Descriptor:Glutamate dehydrogenase 1, mitochondrial
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-27
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD0
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH GTP
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD1
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, CLOSED CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD2
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD3
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, OPEN CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD4
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, CLOSED CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
4UQ6
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ELECTRON DENSITY MAP OF GLUA2EM IN COMPLEX WITH LY451646 AND GLUTAMATE
Descriptor:GLUTAMATE RECEPTOR 2, GLUTAMIC ACID
Authors:Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
Deposit date:2014-06-20
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (12.8 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQJ
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CRYO-EM DENSITY MAP OF GLUA2EM IN COMPLEX WITH ZK200775
Descriptor:GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (10.4 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQK
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ELECTRON DENSITY MAP OF GLUA2EM IN COMPLEX WITH QUISQUALATE AND LY451646
Descriptor:GLUTAMATE RECEPTOR 2, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID
Authors:Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (16.4 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQQ
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ELECTRON DENSITY MAP OF GLUK2 DESENSITIZED STATE IN COMPLEX WITH 2S,4R-4-METHYLGLUTAMATE
Descriptor:GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID
Authors:Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
5A1A
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2.2 A RESOLUTION CRYO-EM STRUCTURE OF BETA-GALACTOSIDASE IN COMPLEX WITH A CELL-PERMEANT INHIBITOR
Descriptor:BETA-GALACTOSIDASE, 2-phenylethyl 1-thio-beta-D-galactopyranoside, MAGNESIUM ION, ...
Authors:Bartesaghi, A., Merk, A., Banerjee, S., Matthies, D., Wu, X., Milne, J., Subramaniam, S.
Deposit date:2015-04-29
Release date:2015-05-06
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:2.2 A Resolution Cryo-Em Structure of Beta-Galactosidase in Complex with a Cell-Permeant Inhibitor
Science, 348, 2015
5FTJ
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO UPCDC30245 INHIBITOR
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE, 1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTK
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ADP
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTL
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I)
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTM
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II)
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTN
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION III)
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5K0Z
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CRYO-EM STRUCTURE OF LACTATE DEHYDROGENASE (LDH) IN INHIBITOR-BOUND STATE
Descriptor:L-lactate dehydrogenase B chain
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K10
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CRYO-EM STRUCTURE OF ISOCITRATE DEHYDROGENASE (IDH1)
Descriptor:Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K11
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CRYO-EM STRUCTURE OF ISOCITRATE DEHYDROGENASE (IDH1) IN INHIBITOR-BOUND STATE
Descriptor:Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K12
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CRYO-EM STRUCTURE OF GLUTAMATE DEHYDROGENASE AT 1.8 A RESOLUTION
Descriptor:Glutamate dehydrogenase 1, mitochondrial
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (1.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016