Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3QUM
DownloadVisualize
BU of 3qum by Molmil
Crystal structure of human prostate specific antigen (PSA) in Fab sandwich with a high affinity and a PCa selective antibody
Descriptor: Fab 5D3D11 Heavy Chain, Fab 5D3D11 Light Chain, Fab 5D5A5 Heavy Chain, ...
Authors:Stura, E.A, Muller, B.H, Michel, S, Ducancel, F.
Deposit date:2011-02-24
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of human prostate-specific antigen in a sandwich antibody complex.
J.Mol.Biol., 414, 2011
2C8G
DownloadVisualize
BU of 2c8g by Molmil
Structure of the PN loop Q182A mutant C3bot1 Exoenzyme (Free state, crystal form I)
Descriptor: MONO-ADP-RIBOSYLTRANSFERASE C3, SULFATE ION
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Properties of Wild-Type and Two Artt Motif Mutants Clostridium Botulinum C3 Exoenzyme Isoform 1 in Different Substrate Complexed States and Crystal Forms.
To be Published
2C8H
DownloadVisualize
BU of 2c8h by Molmil
Structure of the PN loop Q182A mutant C3bot1 Exoenzyme (NAD-bound state, crystal form I)
Descriptor: MONO-ADP-RIBOSYLTRANSFERASE C3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Properties of Wild-Type and Two Artt Motif Mutants Clostridium Botulinum C3 Exoenzyme Isoform 1 in Different Substrate Complexed States and Crystal Forms.
To be Published
4ELC
DownloadVisualize
BU of 4elc by Molmil
Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134 mutant with MTSEA modified Cys-165
Descriptor: (2S)-2-hydroxybutanedioic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Botulinum neurotoxin A light chain, ...
Authors:Stura, E.A, Vera, L, Ptchelkine, D, Bakirci, H, Garcia, S, Dive, V.
Deposit date:2012-04-10
Release date:2012-08-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165.
J.Biol.Chem., 287, 2012
4FVL
DownloadVisualize
BU of 4fvl by Molmil
Human collagenase 3 (MMP-13) full form with peptides from pro-domain
Descriptor: CALCIUM ION, CHLORIDE ION, Collagenase 3, ...
Authors:Stura, E.A, Vera, L, Visse, R, Nagase, H, Dive, V.
Deposit date:2012-06-29
Release date:2013-08-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.436 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
4G0D
DownloadVisualize
BU of 4g0d by Molmil
Human collagenase 3 (MMP-13) full form with peptides from pro-domain
Descriptor: CALCIUM ION, CHLORIDE ION, Collagenase 3, ...
Authors:Stura, E.A, Vera, L, Visse, R, Nagase, H, Dive, V.
Deposit date:2012-07-09
Release date:2013-08-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
4FU4
DownloadVisualize
BU of 4fu4 by Molmil
Human collagenase 3 (MMP-13) with peptide from pro-domain
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Stura, E.A, Vera, L, Visse, R, Nagase, H, Dive, V.
Deposit date:2012-06-28
Release date:2013-08-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
4EL4
DownloadVisualize
BU of 4el4 by Molmil
Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S/C165S double mutant
Descriptor: 1,2-ETHANEDIOL, Botulinum neurotoxin A light chain, GLYCEROL, ...
Authors:Stura, E.A, Vera, L, Ptchelkine, D, Dive, V.
Deposit date:2012-04-10
Release date:2012-08-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165.
J.Biol.Chem., 287, 2012
4EJ5
DownloadVisualize
BU of 4ej5 by Molmil
Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A wild-type
Descriptor: 1,2-ETHANEDIOL, Botulinum neurotoxin A light chain, CARBONATE ION, ...
Authors:Stura, E.A, Vera, L, Dive, V.
Deposit date:2012-04-06
Release date:2012-08-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165.
J.Biol.Chem., 287, 2012
5MG9
DownloadVisualize
BU of 5mg9 by Molmil
Putative Ancestral Mamba toxin 1 (AncTx1-W28R/I38S)
Descriptor: 1,2-ETHANEDIOL, AncTx1-W28R/I38S, S-1,2-PROPANEDIOL, ...
Authors:Stura, E.A, Tepshi, L, Blanchet, G, Mourier, G, Servent, D.
Deposit date:2016-11-21
Release date:2017-05-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins.
Sci Rep, 7, 2017
4WZV
DownloadVisualize
BU of 4wzv by Molmil
Crystal structure of a hydroxamate based inhibitor EN140 in complex with the MMP-9 catalytic domain
Descriptor: (2R)-4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-hydroxy-2-{[(4'-methoxybiphenyl-4-yl)sulfonyl](propan-2-yloxy)amino}butanamide, 1,2-ETHANEDIOL, AZIDE ION, ...
Authors:Stura, E.A, Vera, L, Cassar-Lajeunesse, E, Nuti, E, Dive, V, Rossello, A.
Deposit date:2014-11-20
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
J.Med.Chem., 58, 2015
4XCT
DownloadVisualize
BU of 4xct by Molmil
Crystal structure of a hydroxamate based inhibitor ARP101 (EN73) in complex with the MMP-9 catalytic domain.
Descriptor: (2S,3S)-butane-2,3-diol, (2~{R})-3-methyl-~{N}-oxidanylidene-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxy-amino]butanamide, 1,2-ETHANEDIOL, ...
Authors:Stura, E.A, Tepshi, L, Nuti, E, Dive, V, Cassar-Lajeunesse, E, Vera, L, Rossello, A.
Deposit date:2014-12-18
Release date:2015-04-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
J.Med.Chem., 58, 2015
2C89
DownloadVisualize
BU of 2c89 by Molmil
Structure of the wild-type C3bot1 Exoenzyme (Free state, crystal form I)
Descriptor: MONO-ADP-RIBOSYLTRANSFERASE C3, SULFATE ION
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
Protein Sci., 17, 2008
2C8C
DownloadVisualize
BU of 2c8c by Molmil
Structure of the ARTT motif Q212A mutant C3bot1 Exoenzyme (NAD-bound state, crystal form I)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MONO-ADP-RIBOSYLTRANSFERASE C3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
Protein Sci., 17, 2008
2C8D
DownloadVisualize
BU of 2c8d by Molmil
Structure of the ARTT motif Q212A mutant C3bot1 Exoenzyme (Free state, crystal form I)
Descriptor: MONO-ADP-RIBOSYLTRANSFERASE C3, SULFATE ION
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
Protein Sci., 17, 2008
2C8E
DownloadVisualize
BU of 2c8e by Molmil
Structure of the ARTT motif E214N mutant C3bot1 Exoenzyme (Free state, crystal form III)
Descriptor: MONO-ADP-RIBOSYLTRANSFERASE C3, SULFATE ION
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
Protein Sci., 17, 2008
2C8B
DownloadVisualize
BU of 2c8b by Molmil
Structure of the ARTT motif Q212A mutant C3bot1 Exoenzyme (Free state, crystal form II)
Descriptor: MONO-ADP-RIBOSYLTRANSFERASE C3, SULFATE ION
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
Protein Sci., 17, 2008
2C8F
DownloadVisualize
BU of 2c8f by Molmil
Structure of the ARTT motif E214N mutant C3bot1 Exoenzyme (NAD-bound state, crystal form III)
Descriptor: MONO-ADP-RIBOSYLTRANSFERASE C3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
Protein Sci., 17, 2008
2C8A
DownloadVisualize
BU of 2c8a by Molmil
Structure of the wild-type C3bot1 Exoenzyme (Nicotinamide-bound state, crystal form I)
Descriptor: MONO-ADP-RIBOSYLTRANSFERASE C3, NICOTINAMIDE, SULFATE ION
Authors:Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
Deposit date:2005-12-03
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
Protein Sci., 17, 2008
5I12
DownloadVisualize
BU of 5i12 by Molmil
Crystal structure of the catalytic domain of MMP-9 in complex with a selective sugar-conjugated arylsulfonamide carboxylate water-soluble inhibitor (DC27).
Descriptor: (2R)-2-[{(E)-2-[({(2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-bis(acetyloxy)-6-[(acetyloxy)methyl]tetrahydro-2H-pyran-2-yl}carbamothioyl)amino]ethenyl}(biphenyl-4-ylsulfonyl)amino]-3-methylbutanoic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Stura, E.A, Rosalia, L, Cuffaro, D, Tepshi, L, Ciccone, L, Rossello, A.
Deposit date:2016-02-05
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
Chemmedchem, 11, 2016
5I3M
DownloadVisualize
BU of 5i3m by Molmil
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated thiourea-linked carboxylate zinc-chelator water-soluble inhibitor (DC31).
Descriptor: (2S)-2-{[2-({[(2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]carbamothioyl}amino)ethyl](biphenyl-4-ylsulfonyl)amino}-3-methylbutanoic acid (non-preferred name), 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ...
Authors:Stura, E.A, Rosalia, L, Cuffaro, D, Tepshi, L, Ciccone, L, Rossello, A.
Deposit date:2016-02-10
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
Chemmedchem, 11, 2016
5I2Z
DownloadVisualize
BU of 5i2z by Molmil
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelating water-soluble inhibitor (DC24).
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DIMETHYL SULFOXIDE, ...
Authors:Stura, E.A, Rosalia, L, Cuffaro, D, Tepshi, L, Ciccone, L, Rossello, A.
Deposit date:2016-02-09
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
Chemmedchem, 11, 2016
5I0L
DownloadVisualize
BU of 5i0l by Molmil
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated arylsulfonamide carboxylate water-soluble inhibitor (DC27).
Descriptor: (2R)-2-[{(E)-2-[({(2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-bis(acetyloxy)-6-[(acetyloxy)methyl]tetrahydro-2H-pyran-2-yl}carbamothioyl)amino]ethenyl}(biphenyl-4-ylsulfonyl)amino]-3-methylbutanoic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Stura, E.A, Rosalia, L, Cuffaro, D, Tepshi, L, Ciccone, L, Rossello, A.
Deposit date:2016-02-04
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
Chemmedchem, 11, 2016
5I4O
DownloadVisualize
BU of 5i4o by Molmil
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate zinc-chelator water-soluble inhibitor (DC28).
Descriptor: CALCIUM ION, Macrophage metalloelastase, N-({1-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-1H-1,2,3-triazol-4-yl}methyl)-N-[([1,1'-biphenyl]-4-yl)sulfonyl]-D-valine, ...
Authors:Stura, E.A, Rosalia, L, Cuffaro, D, Tepshi, L, Ciccone, L, Rossello, A.
Deposit date:2016-02-12
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
Chemmedchem, 11, 2016
4TQI
DownloadVisualize
BU of 4tqi by Molmil
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid in a dual binding mode
Descriptor: (2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid, GLYCEROL, Transthyretin
Authors:Stura, E.A, Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E.
Deposit date:2014-06-11
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon