5LB1
| Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) BC-module with thionitrobenzoate (TNB) adduct at the active site cysteine-354 | Descriptor: | 5-MERCAPTO-2-NITRO-BENZOIC ACID, L,D-transpeptidase 2 | Authors: | Steiner, E.M, Schnell, R, Schneider, G. | Deposit date: | 2016-06-15 | Release date: | 2017-01-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Binding and processing of beta-lactam antibiotics by the transpeptidase LdtMt2 from Mycobacterium tuberculosis. FEBS J., 284, 2017
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5LBG
| Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) BC-module with faropenem-derived adduct at the active site cysteine-354 | Descriptor: | (3S)-3-HYDROXYBUTANOIC ACID, L,D-transpeptidase 2 | Authors: | Steiner, E.M, Schnell, R, Schneider, G. | Deposit date: | 2016-06-16 | Release date: | 2017-01-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Binding and processing of beta-lactam antibiotics by the transpeptidase LdtMt2 from Mycobacterium tuberculosis. FEBS J., 284, 2017
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6EWY
| RipA Peptidoglycan hydrolase (Rv1477, Mycobacterium tuberculosis) N-terminal domain | Descriptor: | Peptidoglycan endopeptidase RipA | Authors: | Schnell, R, Steiner, E.M, Schneider, G, Guy, J, Bourenkov, G. | Deposit date: | 2017-11-07 | Release date: | 2018-05-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of the N-terminal module of the cell wall hydrolase RipA and its role in regulating catalytic activity. Proteins, 86, 2018
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4LJ1
| RipD (Rv1566c) from Mycobacterium tuberculosis: a non-catalytic NlpC/p60 domain protein with two penta-peptide repeat units (PVQQA-PVQPA) | Descriptor: | Invasion-associated protein | Authors: | Both, D, Steiner, E.M, Linder, D.C, Schnell, R, Schneider, G. | Deposit date: | 2013-07-04 | Release date: | 2013-11-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function. Biochem.J., 457, 2014
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7B75
| Cryo-EM Structure of Human Thyroglobulin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thyroglobulin, ... | Authors: | Adaixo, R, Righetto, R, Steiner, E.M, Taylor, N.M.I, Stahlberg, H. | Deposit date: | 2020-12-09 | Release date: | 2021-12-29 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of native human thyroglobulin. Nat Commun, 13, 2022
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7A10
| LppS with covalent adduct derived from 1g | Descriptor: | 4-methoxycyclohexa-2,5-diene-1-thione, L,D-transpeptidase 2 | Authors: | Schnell, R, Steiner, E.M. | Deposit date: | 2020-08-11 | Release date: | 2021-04-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
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7A0Z
| LppS with covalent adduct derived from 1b | Descriptor: | L,D-transpeptidase 2, TRIS(HYDROXYETHYL)AMINOMETHANE, benzenethiol | Authors: | Schnell, R, Steiner, E.M. | Deposit date: | 2020-08-11 | Release date: | 2021-04-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
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7A1E
| LppS with covalent adduct derived from 1c | Descriptor: | ACETATE ION, L,D-transpeptidase 2, phenylmethanethiol | Authors: | Schnell, R, Steiner, E.M. | Deposit date: | 2020-08-12 | Release date: | 2021-04-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
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7A1C
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7A11
| LppS with covalent adduct derived from 1E | Descriptor: | ACETATE ION, L,D-transpeptidase 2, propane-1-thiol | Authors: | Schnell, R, Steiner, E.M. | Deposit date: | 2020-08-11 | Release date: | 2021-04-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
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4JXB
| RipD (Rv1566c) from Mycobacterium tuberculosis: a non-catalytic NlpC/p60 domain protein, adaptation to peptidoglycan-binding function | Descriptor: | ACETATE ION, Invasion-associated protein | Authors: | Both, D, Steiner, E.M, Schnell, R, Schneider, G. | Deposit date: | 2013-03-28 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function. Biochem.J., 457, 2014
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4HU2
| Crystal structure of LdtMt2, a L,D-transpeptidase from Mycobacterium tuberculosis: domain A and B | Descriptor: | PROBABLE CONSERVED LIPOPROTEIN LPPS, SULFATE ION | Authors: | Both, D, Steiner, E, Lindqvist, Y, Schnell, R, Schneider, G. | Deposit date: | 2012-11-02 | Release date: | 2012-12-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structure of LdtMt2, an L,D-transpeptidase from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 69, 2013
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4HUC
| Crystal structure of LdtMt2, a L,D-transpeptidase from Mycobacterium tuberculosis: domain B and C | Descriptor: | ACETATE ION, PROBABLE CONSERVED LIPOPROTEIN LPPS, SODIUM ION | Authors: | Both, D, Steiner, E, Lindqvist, Y, Schnell, R, Schneider, G. | Deposit date: | 2012-11-02 | Release date: | 2012-12-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure of LdtMt2, an L,D-transpeptidase from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 69, 2013
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