5LB1

Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) BC-module with thionitrobenzoate (TNB) adduct at the active site cysteine-354

Summary for 5LB1

• Entry DOI: 10.2210/pdb5lb1/pdb
• Related: 4HUC
• Descriptor: L,D-transpeptidase 2, 5-MERCAPTO-2-NITRO-BENZOIC ACID (3 entities in total)
• Functional Keywords: cell wall, peptidoglycan, transpeptidase, mycobacterium tuberculosis, transferase
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cell membrane ; Lipid-anchor : I6Y9J2
• Total number of polymer chains: 2
• Total formula weight: 57415.66

Authors

Steiner, E.M.,Schnell, R.,Schneider, G. (deposition date: 2016-06-15, release date: 2017-01-18, Last modification date: 2024-01-10)

• Primary citation: Steiner, E.M.,Schneider, G.,Schnell, R.; Binding and processing of beta-lactam antibiotics by the transpeptidase LdtMt2 from Mycobacterium tuberculosis.; FEBS J., 284:725-741, 2017; PubMed: 28075068; DOI: 10.1111/febs.14010

Experimental method

X-RAY DIFFRACTION (1.55 Å)