2LGV
 
 | | Rbx1 | | Descriptor: | E3 ubiquitin-protein ligase RBX1, ZINC ION | | Authors: | Spratt, D.E, Shaw, G.S. | | Deposit date: | 2011-08-02 | | Release date: | 2012-03-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Selective recruitment of an e2~ubiquitin complex by an e3 ubiquitin ligase.
J.Biol.Chem., 287, 2012
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2M48
 | | Solution Structure of IBR-RING2 Tandem Domain from Parkin | | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION | | Authors: | Noh, Y.J, Mercier, P, Spratt, D.E, Shaw, G.S. | | Deposit date: | 2013-01-30 | | Release date: | 2013-05-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
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2LWR
 | | Solution Structure of RING2 Domain from Parkin | | Descriptor: | SD01679p, ZINC ION | | Authors: | Mercier, P, Spratt, D.E, Manczyk, N, Shaw, G.S. | | Deposit date: | 2012-08-06 | | Release date: | 2013-06-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
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2M9Y
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5W87
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8F36
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8F37
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5C23
 | | Parkin (S65DUblR0RBR) | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | Authors: | Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | | Deposit date: | 2015-06-15 | | Release date: | 2015-07-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
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5C1Z
 | | Parkin (UblR0RBR) | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | Authors: | kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | | Deposit date: | 2015-06-15 | | Release date: | 2015-07-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
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2LL7
 | | Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide | | Descriptor: | Calmodulin, Nitric oxide synthase, endothelial | | Authors: | Piazza, M, Futrega, K, Spratt, D.E, Guillemette, J.G, Dieckmann, T. | | Deposit date: | 2011-10-29 | | Release date: | 2012-05-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
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2LL6
 | | Solution NMR structure of CaM bound to iNOS CaM binding domain peptide | | Descriptor: | Calmodulin, Nitric oxide synthase, inducible | | Authors: | Piazza, M, Futrega, K, Spratt, D.E, Dieckmann, T, Guillemette, J.G. | | Deposit date: | 2011-10-29 | | Release date: | 2012-05-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
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6TGK
 | | Domain swapped E6AP C-lobe dimer | | Descriptor: | ACETATE ION, CALCIUM ION, Ubiquitin-protein ligase E3A | | Authors: | Ries, L.K, Feiler, C, Lowe, L.D, Liess, A.K.L, Lorenz, S. | | Deposit date: | 2019-11-16 | | Release date: | 2020-02-26 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal structure of the catalytic C-lobe of the HECT-type ubiquitin ligase E6AP.
Protein Sci., 29, 2020
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9NCR
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9NB0
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9YZR
 | | Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence TAATTAGGCCG and loaded with ultrabithorax homeodomain | | Descriptor: | DNA (31-MER), Homeotic protein ultrabithorax, MAGNESIUM ION, ... | | Authors: | Shields, E.T, Slaughter, C.K, Magna, E.N, Snow, C.D. | | Deposit date: | 2025-10-30 | | Release date: | 2026-02-18 | | Method: | X-RAY DIFFRACTION (3.39 Å) | | Cite: | Modular Scaffold Crystals for Programmable Installation and Structural Observation of DNA-Binding Proteins
To Be Published
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9YZB
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9YZI
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9Z1D
 | | Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence GCTTGATGAG, crystal soaked in alternate solvent prior to diffraction | | Descriptor: | DNA (31-MER), MAGNESIUM ION, Replication initiation protein | | Authors: | Shields, E.T, Slaughter, C.K, Magna, E.N, Snow, C.D. | | Deposit date: | 2025-11-03 | | Release date: | 2026-02-18 | | Method: | X-RAY DIFFRACTION (3.06 Å) | | Cite: | Modular Scaffold Crystals for Programmable Installation and Structural Observation of DNA-Binding Proteins
To Be Published
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9YZA
 | | Isoreticular co-crystal 1 of protein variant Replication Initiator Protein REPE54 (L53G, Q54G, E55G) with symmetrical expanded duplex (31mer) containing insert sequence CCCGGCCGGA | | Descriptor: | DNA (31-MER), MAGNESIUM ION, Replication initiation protein | | Authors: | Shields, E.T, Slaughter, C.K, Magna, E.N, Snow, C.D. | | Deposit date: | 2025-10-30 | | Release date: | 2026-02-18 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Modular Scaffold Crystals for Programmable Installation and Structural Observation of DNA-Binding Proteins
To Be Published
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9YZG
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9YZS
 | | Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence TAATTAGGCCG and loaded with Even-skipped homeodomain | | Descriptor: | DNA (31-MER), MAGNESIUM ION, Replication initiation protein, ... | | Authors: | Shields, E.T, Slaughter, C.K, Magna, E.N, Snow, C.D. | | Deposit date: | 2025-10-30 | | Release date: | 2026-02-18 | | Method: | X-RAY DIFFRACTION (3.08 Å) | | Cite: | Modular Scaffold Crystals for Programmable Installation and Structural Observation of DNA-Binding Proteins
To Be Published
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9YZC
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9YZK
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9YZJ
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9YZM
 | | Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence CTAATTAGGC and loaded with Even-skipped homeodomain | | Descriptor: | DNA (31-MER), MAGNESIUM ION, Replication initiation protein, ... | | Authors: | Shields, E.T, Slaughter, C.K, Magna, E.N, Snow, C.D. | | Deposit date: | 2025-10-30 | | Release date: | 2026-02-18 | | Method: | X-RAY DIFFRACTION (3.07 Å) | | Cite: | Modular Scaffold Crystals for Programmable Installation and Structural Observation of DNA-Binding Proteins
To Be Published
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