Author results

2LGV
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RBX1
Descriptor:E3 ubiquitin-protein ligase RBX1, ZINC ION
Authors:Spratt, D.E., Shaw, G.S.
Deposit date:2011-08-02
Release date:2012-03-28
Last modified:2012-06-06
Method:SOLUTION NMR
Cite:Selective recruitment of an e2~ubiquitin complex by an e3 ubiquitin ligase.
J.Biol.Chem., 287, 2012
2LWR
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SOLUTION STRUCTURE OF RING2 DOMAIN FROM PARKIN
Descriptor:SD01679p, ZINC ION
Authors:Mercier, P., Spratt, D.E., Manczyk, N., Shaw, G.S.
Deposit date:2012-08-06
Release date:2013-06-12
Last modified:2014-10-15
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
2M48
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SOLUTION STRUCTURE OF IBR-RING2 TANDEM DOMAIN FROM PARKIN
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION
Authors:Noh, Y.J., Mercier, P., Spratt, D.E., Shaw, G.S.
Deposit date:2013-01-30
Release date:2013-05-15
Last modified:2014-10-15
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
2M9Y
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SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HHARI
Descriptor:E3 ubiquitin-protein ligase ARIH1, ZINC ION
Authors:Mercier, P., Spratt, D.E., Shaw, G.S.
Deposit date:2013-06-24
Release date:2013-11-13
Method:SOLUTION NMR
Cite:Structure of the HHARI catalytic domain shows glimpses of a HECT E3 ligase.
Plos One, 8, 2013
2LL6
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SOLUTION NMR STRUCTURE OF CAM BOUND TO INOS CAM BINDING DOMAIN PEPTIDE
Descriptor:Calmodulin, Nitric oxide synthase, inducible
Authors:Piazza, M., Futrega, K., Spratt, D.E., Dieckmann, T., Guillemette, J.G.
Deposit date:2011-10-29
Release date:2012-05-16
Method:SOLUTION NMR
Cite:Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
2LL7
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SOLUTION NMR STRUCTURE OF CAM BOUND TO THE ENOS CAM BINDING DOMAIN PEPTIDE
Descriptor:Calmodulin, Nitric oxide synthase, endothelial
Authors:Piazza, M., Futrega, K., Spratt, D.E., Guillemette, J.G., Dieckmann, T.
Deposit date:2011-10-29
Release date:2012-05-16
Method:SOLUTION NMR
Cite:Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
5C1Z
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PARKIN (UBLR0RBR)
Descriptor:E3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ...
Authors:kumar, A., Aguirre, J.D., Condos, T.E.C., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C23
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PARKIN (S65DUBLR0RBR)
Descriptor:E3 ubiquitin-protein ligase parkin, ZINC ION, GLYCEROL, ...
Authors:Kumar, A., Aguirre, J.D., Condos, T.E.C., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5W87
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CRYSTAL STRUCTURE OF THE C-TERMINAL LOBE OF THE HUMAN HERC6 HECT DOMAIN
Descriptor:Probable E3 ubiquitin-protein ligase HERC6, PHOSPHATE ION
Authors:WANG, Y., BELLESIS, A.G., ROYER, W.E., SPRATT, D.E.
Deposit date:2017-06-21
Release date:2018-07-04
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Crystal structure of the C-terminal lobe of the human HERC6 HECT domain
To Be Published