4X6L
| Crystal structure of S. aureus TarM in complex with UDP | Descriptor: | TarM, URIDINE-5'-DIPHOSPHATE | Authors: | Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C. | Deposit date: | 2014-12-08 | Release date: | 2015-02-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4X7P
| Crystal structure of apo S. aureus TarM | Descriptor: | SULFATE ION, TarM | Authors: | Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C. | Deposit date: | 2014-12-09 | Release date: | 2015-02-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4X7M
| Crystal structure of S. aureus TarM G117R mutant in complex with UDP and UDP-GlcNAc | Descriptor: | TarM, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Worrall, L.J, Sobhanifar, S, Strynadka, N.C. | Deposit date: | 2014-12-09 | Release date: | 2015-03-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4X7R
| Crystal structure of S. aureus TarM G117R mutant in complex with Fondaparinux, alpha-GlcNAc-glycerol and UDP | Descriptor: | (2S)-2,3-dihydroxypropyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, TarM, ... | Authors: | Worrall, L.J, Sobhanifar, S, Strynadka, N.C. | Deposit date: | 2014-12-09 | Release date: | 2015-02-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
5TZ8
| Crystal structure of S. aureus TarS | Descriptor: | Glycosyl transferase | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
|
|
5TZI
| Crystal structure of S. aureus TarS 1-349 | Descriptor: | Glycosyl transferase | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
|
|
5U02
| Crystal structure of S. aureus TarS 217-571 | Descriptor: | Glycosyl transferase, IMIDAZOLE | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-22 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
|
|
5TZJ
| Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc | Descriptor: | Glycosyl transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
|
|
5TZE
| Crystal structure of S. aureus TarS in complex with UDP-GlcNAc | Descriptor: | Glycosyl transferase, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
|
|
5TZK
| Crystal structure of S. aureus TarS 1-349 in complex with UDP | Descriptor: | Glycosyl transferase, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
|
|
7L3N
| SARS-CoV 2 Spike Protein bound to LY-CoV555 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV555 Fab heavy chain, ... | Authors: | Goldsmith, J.A, McLellan, J.S. | Deposit date: | 2020-12-18 | Release date: | 2021-02-03 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection. Biorxiv, 2020
|
|
7KMI
| LY-CoV481 neutralizing antibody against SARS-CoV-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LY-CoV481 Fab heavy chain, ... | Authors: | Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D. | Deposit date: | 2020-11-02 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. Sci Transl Med, 13, 2021
|
|
7KMG
| LY-CoV555 neutralizing antibody against SARS-CoV-2 | Descriptor: | GLYCEROL, LY-CoV555 Fab heavy chain, LY-CoV555 Fab light chain, ... | Authors: | Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D. | Deposit date: | 2020-11-02 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. Sci Transl Med, 13, 2021
|
|
7KMH
| LY-CoV488 neutralizing antibody against SARS-CoV-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LY-CoV488 Fab heavy chain, ... | Authors: | Hendle, J, Pustilnik, A, Sauder, J.M, Boyles, J.S, Dickinson, C.D, Coleman, K.A. | Deposit date: | 2020-11-02 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. Sci Transl Med, 13, 2021
|
|
8EXP
| Cryo-EM structure of S. aureus BlaR1 with C2 symmetry | Descriptor: | Beta-lactam sensor/signal transducer BlaR1, ZINC ION | Authors: | Worrall, L.J, Alexander, J.A.N, Vuckovic, M, Strynadka, N.C.J. | Deposit date: | 2022-10-25 | Release date: | 2023-01-11 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus. Nature, 613, 2023
|
|
8EXS
| Cryo-EM structure of S. aureus BlaR1 F284A mutant | Descriptor: | Beta-lactam sensor/signal transducer BlaR1, ZINC ION | Authors: | Alexander, J.A.N, Hu, J, Worrall, L.J, Strynadka, N.C.J. | Deposit date: | 2022-10-25 | Release date: | 2023-01-11 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus. Nature, 613, 2023
|
|
8EXR
| Cryo-EM structure of S. aureus BlaR1 TM and zinc metalloprotease domain | Descriptor: | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Beta-lactam sensor/signal transducer BlaR1, PHOSPHATE ION, ... | Authors: | Worrall, L.J, Alexander, J.A.N, Vuckovic, M, Strynadka, N.C.J. | Deposit date: | 2022-10-25 | Release date: | 2023-01-11 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus. Nature, 613, 2023
|
|
8EXT
| Cryo-EM structure of S. aureus BlaR1 F284A mutant in complex with ampicillin | Descriptor: | Beta-lactam sensor/signal transducer BlaR1, ZINC ION | Authors: | Alexander, J.A.N, Hu, J, Worrall, L.J, Strynadka, N.C.J. | Deposit date: | 2022-10-25 | Release date: | 2023-01-11 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus. Nature, 613, 2023
|
|
8EXQ
| Cryo-EM structure of S. aureus BlaR1 with C1 symmetry | Descriptor: | Beta-lactam sensor/signal transducer BlaR1, ZINC ION | Authors: | Worrall, L.J, Alexander, J.A.N, Vuckovic, M, Strynadka, N.C.J. | Deposit date: | 2022-10-25 | Release date: | 2023-01-11 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus. Nature, 613, 2023
|
|