Author results

1OXG
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CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN ORGANIC SOLVENT TREATED BOVINE ALPHA-CHYMOTRYPSIN AND ITS AUTOCATALYTICALLY PRODUCED HIGHLY POTENT 14-RESIDUE PEPTIDE AT 2.2 RESOLUTION
Descriptor:Chymotrypsinogen A, SULFATE ION
Authors:Singh, N., Jabeen, T., Sharma, S., Roy, I., Gupta, M.N., Bilgrami, S., Singh, T.P.
Deposit date:2003-04-02
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Detection of native peptides as potent inhibitors of enzymes. Crystal structure of the complex formed between treated bovine alpha-chymotrypsin and an autocatalytically produced fragment, IIe-Val-Asn-Gly-Glu-Glu-Ala-Val-Pro-Gly-Ser-Trp-Pro-Trp, at 2.2 angstroms resolution.
Febs J., 272, 2005
1OYF
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CRYSTAL STRUCTURE OF RUSSELLES VIPER (DABOIA RUSSELLII PULCHELLA) PHOSPHOLIPASE A2 IN A COMPLEX WITH VENOM 6-METHYL HEPTANOL
Descriptor:Phospholipase A2, SULFATE ION, 6-METHYLHEPTAN-1-OL, ...
Authors:Singh, N., Jabeen, T., Sharma, S., Singh, T.P.
Deposit date:2003-04-04
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of Russelles viper (Daboia russellii pulchella) phospholipase A2 in a complex with venom 6-methyl heptanol
To be Published
1OYO
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REGULATION OF PROTEASE ACTIVITY BY MELANIN: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PROTEINASE K AND MELANIN MONOMERS AT 2.0 RESOLUTION
Descriptor:Proteinase K, CALCIUM ION, 3H-INDOLE-5,6-DIOL
Authors:Singh, N., Sharma, S., Kumar, S., Raman, G., Singh, T.P.
Deposit date:2003-04-06
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Regulation of protease activity by melanin: Crystal structure of the complex formed between proteinase K and melanin monomers at 2.0 resolution
To be Published
1Q6V
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FIRST CRYSTAL STRUCTURE OF A C49 MONOMER PLA2 FROM THE VENOM OF DABOIA RUSSELLI PULCHELLA AT 1.8 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N., Pal, A., Jabeen, T., Sharma, S., Singh, T.P.
Deposit date:2003-08-14
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:First crystal structure of a C49 PLA2 from the venom of Daboia russelli pulchella at 1.8A resolution
To be Published
1Q7A
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN RUSSELL'S VIPER PHOSPHOLIPASE A2 AND AN ANTIINFLAMMATORY AGENT OXYPHENBUTAZONE AT 1.6A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE, ...
Authors:Singh, N., Jabeen, T., Sharma, S., Singh, T.P.
Deposit date:2003-08-17
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution.
Biochemistry, 43, 2004
1SQZ
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DESIGN OF SPECIFIC INHIBITORS OF PHOPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN GROUP II PHOPHOLIPASE A2 AND A DESIGNED PEPTIDE DEHYDRO-ILE-ALA-ARG-SER AT 1.2A RESOLUTION
Descriptor:Phospholipase A2, synthetic peptide, SULFATE ION
Authors:Singh, N., Prem Kumar, R., Somvanshi, R.K., Bilgrami, S., Ethayathulla, A.S., Sharma, S., Dey, S., Singh, T.P.
Deposit date:2004-03-22
Release date:2004-04-13
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Design of specific inhibitors of Phopholipase A2: Crystal structure of the complex formed between GroupII Phopholipase A2 and a designed peptide Dehydro-Ile-Ala-Arg-Ser at 1.2A resolution
To be Published
1SV3
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STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND 4-METHOXYBENZOIC ACID AT 1.3A RESOLUTION.
Descriptor:Phospholipase A2, SULFATE ION, 4-METHOXYBENZOIC ACID
Authors:Singh, N., Prahathees, E., Jabeen, T., Pal, A., Ethayathulla, A.S., Prem kumar, R., Sharma, S., Singh, T.P.
Deposit date:2004-03-27
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding
Proteins, 64, 2006
1SXK
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CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND A NON-SPECIFIC ANTI-INFLAMMATORY AMINO SALICYLIC ACID AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 2-HYDROXY-4-AMINOBENZOIC ACID
Authors:Singh, N., Bilgrami, S., Kaur, P., Sharma, S., Singh, T.P.
Deposit date:2004-03-31
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Crystal Structure of a complex formed between phospholipase A2 and a non-specific anti-inflammatory amino salicylic acid at 1.2 A resolution
To be Published
1TDV
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NON-SPECIFIC BINDING TO PHOSPHOLIPASE A2:CRYSTAL STRUCTURE OF THE COMPLEX OF PLA2 WITH A DESIGNED PEPTIDE TYR-TRP-ALA-ALA-ALA-ALA AT 1.7A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, YWAAAA, SULFATE ION
Authors:Singh, N., Jabeen, T., Ethayathulla, A.S., Somvanshi, R.K., Sharma, S., Dey, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2004-05-24
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Non-specific binding to phospholipase A2:Crystal structure of the complex of PLA2 with a designed peptide Tyr-Trp-Ala-Ala-Ala-Ala at 1.7A resolution
to be published
1TG1
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN RUSSELLS VIPER PHOSPHOLIPASE A2 AND A DESIGNED PEPTIDE INHIBITOR PHQ-LEU-VAL-ARG-TYR AT 1.2A RESOLUTION
Descriptor:Phospholipase A2, peptide inhibitor, SULFATE ION, ...
Authors:Singh, N., Kaur, P., Somvanshi, R.K., Sharma, S., Dey, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2004-05-28
Release date:2004-06-08
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of the complex formed between russells viper phospholipase A2 and a designed peptide inhibitor Cbz-dehydro-Leu-Val-Arg-Tyr at 1.2A resolution
To be Published
1TG4
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DESIGN OF SPECIFIC INHIBITORS OF GROUPII PHOSPHOLIPASE A2(PLA2): CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN RUSSELLS VIPER PLA2 AND DESIGNED PEPTIDE PHE-LEU-ALA-TYR-LYS AT 1.7A RESOLUTION
Descriptor:Phospholipase A2, FLAYK peptide, SULFATE ION
Authors:Singh, N., Somvanshi, R.K., Sharma, S., Dey, S., Perbandt, M., Betzel, C., Ethayathulla, A.S., Singh, T.P.
Deposit date:2004-05-28
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of specific inhibitors of groupII phospholipase A2(PLA2): Crystal structure of the complex formed between russells viper PLA2 and designed peptide Phe-Leu-Ala-Tyr-Lys at 1.7A resolution
TO BE PUBLISHED
1TGM
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CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN GROUP II PHOSPHOLIPASE A2 AND ASPIRIN AT 1.86 A RESOLUTION
Descriptor:Phospholipase A2, 2-(ACETYLOXY)BENZOIC ACID, CALCIUM ION, ...
Authors:Singh, N., Jabeen, T., Sharma, S., Bhushan, A., Singh, T.P.
Deposit date:2004-05-28
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of a complex formed between group II phospholipase A2 and aspirin at 1.86 A resolution
To be Published
1TH6
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CRYSTAL STRUCTURE OF PHOSPHOLIPASE A2 IN COMPLEX WITH ATROPINE AT 1.23A RESOLUTION
Descriptor:Phospholipase A2, (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, SULFATE ION
Authors:Singh, N., Pal, A., Jabeen, T., Sharma, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2004-06-01
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Crystal structure of phospholipase A2 in complex with atropine at 1.23A resolution
To be Published
1TJ9
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STRUCTURE OF THE COMPLEXED FORMED BETWEEN GROUP II PHOSPHOLIPASE A2 AND A RATIONALLY DESIGNED TETRA PEPTIDE,VAL-ALA-ARG-SER AT 1.1A RESOLUTION
Descriptor:Phospholipase A2, VARS peptide, SULFATE ION, ...
Authors:Singh, N., Ethayathulla, A.S., K Somvanshi, R., Sharma, S., Dey, S., Perbandt, M., Betzel, C., Kaur, P., Singh, T.P.
Deposit date:2004-06-03
Release date:2004-06-08
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure of the complex formed between group II phospholipase A2 and a rationally designed tetra peptide,Val-Ala-Arg-Ser at 1.1A resolution
TO BE PUBLISHED
1TJK
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN GROUP II PHOSPHOLIPASE A2 WITH A DESIGNED PENTAPEPTIDE, PHE- LEU- SER- THR- LYS AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2, synthetic peptide, SULFATE ION
Authors:Singh, N., Jabeen, T., Somvanshi, R.K., Sharma, S., Perbandt, M., Dey, S., Betzel, C., Singh, T.P.
Deposit date:2004-06-06
Release date:2004-06-15
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of the complex formed between group II phospholipase A2 with a designed pentapeptide, Phe - Leu - Ser - Thr - Lys at 1.2 A resolution
To be Published
1TK4
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CRYSTAL STRUCTURE OF RUSSELLS VIPER PHOSPHOLIPASE A2 IN COMPLEX WITH A SPECIFICALLY DESIGNED TETRAPEPTIDE ALA-ILE-ARG-SER AT 1.1 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, Tetrapeptide Ala-Ile-Arg-Ser, SULFATE ION
Authors:Singh, N., Bilgrami, S., Somvanshi, R.K., Sharma, S., Dey, S., Perbandt, M., Betzel, C., Kaur, P., Singh, T.P.
Deposit date:2004-06-08
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of russells viper phospholipase A2 with a specifically designed tetrapeptide Ala-Ile-Arg-Ser at 1.1 A resolution
TO BE PUBLISHED
1TP2
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CRYSTAL STRUCTURE OF THE COMPLEX OF GROUP II PHOSPHOLIPASEA2 DIMER WITH A FATTY ACID TRIDECANOIC ACID AT 2.4 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, N-TRIDECANOIC ACID, ...
Authors:Singh, N., Jabeen, T., Sharma, S., Singh, T.P.
Deposit date:2004-06-15
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the complex of group II phospholipaseA2 dimer with a fatty acid tridecanoic acid at 2.4 A resolution
To be Published
1Y38
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 DIMER AND GLYCEROPHOSPHATE AT 2.4 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SODIUM ION, SULFATE ION, ...
Authors:Singh, N., Jabeen, T., Sharma, S., Singh, T.P.
Deposit date:2004-11-24
Release date:2005-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of the complex formed between phospholipase A2 dimer and glycerophosphate at 2.4 A resolution
To be Published
1ZYX
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CRYSTAL STRUCTURE OF THE COMPLEX OF A GROUP IIA PHOSPHOLIPASE A2 WITH A SYNTHETIC ANTI-INFLAMMATORY AGENT LICOFELONE AT 1.9A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, [6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YL]ACETIC ACID
Authors:Singh, N., Jabeen, T., Sharma, S., Bhushan, A., Singh, T.P.
Deposit date:2005-06-13
Release date:2005-06-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the complex of a group IIA phospholipase A2 with a synthetic anti-inflammatory agent licofelone at 1.9A resolution
To be Published
2ALU
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DETECTION OF NEW BINDING SITE IN THE C-TERMINAL LOBE OF LACTOFERRIN:CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN BOVINE LACTOFERRIN AND A TETRASACCHARIDE AT 2.1A RESOLUTION
Descriptor:Lactotransferrin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Singh, N., Jabeen, T., Sharma, S., Bhushan, A., Singh, T.P.
Deposit date:2005-08-08
Release date:2005-09-20
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Detection of new binding site in the C-terminal lobe of lactoferrin:Crystal structure of the complex formed between bovine lactoferrin and a tetrasaccharide at 2.1A resolution
To be Published
2ARM
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CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOLIPASE A2 WITH A NATURAL COMPOUND ATROPINE AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, SULFATE ION
Authors:Singh, N., Pal, A., Jabeen, T., Sharma, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2005-08-20
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding
Proteins, 64, 2006
2AYS
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A CONSERVED NON-METALLIC BINDING SITE IN THE C-TERMINAL LOBE OF LACTOFERRIN: STRUCTURE OF THE COMPLEX OF C-TERMINAL LOBE OF BOVINE LACTOFERRIN WITH N-ACETYL GALACTOSAMINE AT 1.86 A RESOLUTION
Descriptor:Lactotransferrin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Singh, N., Jabeen, T., Sharma, S., Singh, T.P.
Deposit date:2005-09-08
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:A conserved non-metallic binding site in the C-terminal lobe of lactoferrin: Structure of the complex of C-terminal lobe of bovine lactoferrin with N-acetyl galactosamine at 1.86 A resolution
To be Published
2B17
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SPECIFIC BINDING OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) TO PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND DICLOFENAC AT 2.7 A RESOLUTION:
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID
Authors:Singh, N., Jabeen, T., Sharma, S., Singh, T.P.
Deposit date:2005-09-15
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
2B65
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CRYSTAL STRUCTURE OF THE COMPLEX OF C-LOBE OF BOVINE LACTOFERRIN WITH MALTOSE AT 1.5A RESOLUTION
Descriptor:Lactotransferrin, MALTOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Singh, N., Prem kumar, R., Jabeen, T., Kaur, P., Sharma, S., Singh, T.P.
Deposit date:2005-09-30
Release date:2005-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the complex of C-lobe of bovine lactoferrin with maltose at 1.5A resolution
To be published
2DO2
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DESIGN OF SPECIFIC INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN A GROUP II CYS 49 PHOSPHOLIPASE A2 AND A DESIGNED PENTAPEPTIDE ALA-LEU-ALA-SER-LYS AT 2.6A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, Ala-Leu-Ala-Ser-Lys, SULFATE ION
Authors:Singh, N., Sharma, S., Somvanshi, R.K., Dey, S., Singh, T.P.
Deposit date:2006-04-27
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution
To be Published