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1SQZ

Design of specific inhibitors of Phopholipase A2: Crystal structure of the complex formed between Group II Phopholipase A2 and a designed peptide Dehydro-Ile-Ala-Arg-Ser at 1.2A resolution

Summary for 1SQZ
Entry DOI10.2210/pdb1sqz/pdb
Related1FB2
Related PRD IDPRD_000335
DescriptorPhospholipase A2, synthetic peptide, SULFATE ION, ... (4 entities in total)
Functional Keywordsphospholipase a2, dehydro-iars, toxin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceDaboia russellii russellii
More
Cellular locationSecreted: P59071
Total number of polymer chains2
Total formula weight14517.06
Authors
Singh, N.,Prem Kumar, R.,Somvanshi, R.K.,Bilgrami, S.,Ethayathulla, A.S.,Sharma, S.,Dey, S.,Singh, T.P. (deposition date: 2004-03-22, release date: 2004-04-13, Last modification date: 2023-08-23)
Primary citationSingh, N.,Prem Kumar, R.,Somvanshi, R.K.,Bilgrami, S.,Ethayathulla, A.S.,Sharma, S.,Dey, S.,Singh, T.P.
Design of specific inhibitors of Phopholipase A2: Crystal structure of the complex formed between GroupII Phopholipase A2 and a designed peptide Dehydro-Ile-Ala-Arg-Ser at 1.2A resolution
To be Published,
Experimental method
X-RAY DIFFRACTION (1.2 Å)
Structure validation

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