1SQZ

Design of specific inhibitors of Phopholipase A2: Crystal structure of the complex formed between Group II Phopholipase A2 and a designed peptide Dehydro-Ile-Ala-Arg-Ser at 1.2A resolution

Summary for 1SQZ

• Entry DOI: 10.2210/pdb1sqz/pdb
• Related: 1FB2
• Related PRD ID: PRD_000335
• Descriptor: Phospholipase A2, synthetic peptide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: phospholipase a2, dehydro-iars, toxin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Daboia russellii russellii; More
• Cellular location: Secreted: P59071
• Total number of polymer chains: 2
• Total formula weight: 14517.06

Authors

Singh, N.,Prem Kumar, R.,Somvanshi, R.K.,Bilgrami, S.,Ethayathulla, A.S.,Sharma, S.,Dey, S.,Singh, T.P. (deposition date: 2004-03-22, release date: 2004-04-13, Last modification date: 2024-11-06)

• Primary citation: Singh, N.,Prem Kumar, R.,Somvanshi, R.K.,Bilgrami, S.,Ethayathulla, A.S.,Sharma, S.,Dey, S.,Singh, T.P.; Design of specific inhibitors of Phopholipase A2: Crystal structure of the complex formed between GroupII Phopholipase A2 and a designed peptide Dehydro-Ile-Ala-Arg-Ser at 1.2A resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (1.2 Å)