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3V0A
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2.7 ANGSTROM CRYSTAL STRUCTURE OF BONT/AI IN COMPLEX WITH NTNHA
Descriptor:BoNT/A, NTNH, Llama antibody F12, ...
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
3V0B
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3.9 ANGSTROM CRYSTAL STRUCTURE OF BONT/AI IN COMPLEX WITH NTNHA
Descriptor:BoNT/A, NTNH, ZINC ION, ...
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
3V0C
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4.3 ANGSTROM CRYSTAL STRUCTURE OF AN INACTIVE BONT/A (E224Q/R363A/Y366F)
Descriptor:BoNT/A, ZINC ION
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
4LGP
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH1)
Descriptor:Ricin, VHH1 camelid nanobody, CHLORIDE ION, ...
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-06-28
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LGR
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH3)
Descriptor:Ricin, Camelid nanobody (VHH3), ZINC ION, ...
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-06-28
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LGS
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH4)
Descriptor:Ricin, Camelid nanobody (VHH4)
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-06-28
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LHJ
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH5)
Descriptor:Ricin, Camelid antibody, CHLORIDE ION
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-07-01
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LHQ
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH8)
Descriptor:Ricin, Camelid nanobody
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-07-01
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4Z9K
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH2)(F5)
Descriptor:Ricin, VHH2(F5) antibody, 1,2-ETHANEDIOL, ...
Authors:Rudolph, M.J.
Deposit date:2015-04-10
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins, 84, 2016
5E1H
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RICIN TOXIN IN COMPLEX WITH NEUTRALIZING SINGLE CHAIN MONOCLONAL ANTIBODIES (VHHS)
Descriptor:Ricin, F8(JOB10) VHH antibody, CHLORIDE ION
Authors:Rudolph, M.J., Vance, D., Shoemaker, C., Mantis, N.
Deposit date:2015-09-29
Release date:2016-08-03
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins, 84, 2016
5V8P
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SMALL MOLECULE INHIBITOR ABS-143 BOUND TO THE BOTULINUM NEUROTOXIN SEROTYPE A LIGHT CHAIN
Descriptor:Botulinum neurotoxin type A, ZINC ION, N-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-2-sulfanylacetamide
Authors:Allen, K.N., Silvaggi, N.R.
Deposit date:2017-03-22
Release date:2017-07-26
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
Toxicon, 137, 2017
5V8R
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SMALL MOLECULE INHIBITOR ABS-143 BOUND TO THE BOTULINUM NEUROTOXIN SEROTYPE A LIGHT CHAIN
Descriptor:Botulinum neurotoxin type A, ZINC ION, N-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]-2-sulfanylacetamide
Authors:Allen, K.N., Silvaggi, N.R.
Deposit date:2017-03-22
Release date:2017-07-26
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
Toxicon, 137, 2017
5V8U
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SMALL MOLECULE INHIBITOR ABS-143 BOUND TO THE BOTULINUM NEUROTOXIN SEROTYPE A LIGHT CHAIN
Descriptor:Botulinum neurotoxin type A, ZINC ION, N-[3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-yl]-2-sulfanylacetamide
Authors:Allen, K.N., Silvaggi, N.R.
Deposit date:2017-03-22
Release date:2017-07-26
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
Toxicon, 137, 2017
5L21
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CRYSTAL STRUCTURE OF BONT/A RECEPTOR BINDING DOMAIN IN COMPLEX WITH VHH C2
Descriptor:Botulinum neurotoxin type A, VHH-C2
Authors:Yao, G., Jin, R.
Deposit date:2016-07-29
Release date:2017-08-09
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.
Sci Rep, 7, 2017