Author results

1C1Z
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CRYSTAL STRUCTURE OF HUMAN BETA-2-GLYCOPROTEIN-I (APOLIPOPROTEIN-H)
Descriptor:BETA2-GLYCOPROTEIN-I, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Schwarzenbacher, R., Zeth, K., Diederichs, K., Gries, A., Kostner, G.M., Laggner, P., Prassl, R.
Deposit date:1999-07-22
Release date:1999-11-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome.
EMBO J., 18, 1999
1RCW
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CRYSTAL STRUCTURE OF CT610 FROM CHLAMYDIA TRACHOMATIS
Descriptor:CT610, FE (III) ION
Authors:Schwarzenbacher, R., Liddington, R.C.
Deposit date:2003-11-04
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Chlamydia protein CADD reveals a redox enzyme that modulates host cell apoptosis.
J.Biol.Chem., 279, 2004
3EZQ
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CRYSTAL STRUCTURE OF THE FAS/FADD DEATH DOMAIN COMPLEX
Descriptor:Tumor necrosis factor receptor superfamily member 6, Protein FADD, SULFATE ION, ...
Authors:Schwarzenbacher, R., Robinson, H., Stec, B., Riedl, S.J.
Deposit date:2008-10-23
Release date:2008-12-23
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:The Fas-FADD death domain complex structure unravels signalling by receptor clustering
Nature, 457, 2009
1PWP
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CRYSTAL STRUCTURE OF THE ANTHRAX LETHAL FACTOR COMPLEXED WITH SMALL MOLECULE INHIBITOR NSC 12155
Descriptor:Lethal factor, ZINC ION, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA
Authors:Wong, T.Y., Schwarzenbacher, R., Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification of small molecule inhibitors of anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
2KM6
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NMR STRUCTURE OF THE NLRP7 PYRIN DOMAIN
Descriptor:NACHT, LRR and PYD domains-containing protein 7
Authors:Pinheiro, A., Proell, M., Schwarzenbacher, R., Peti, W.
Deposit date:2009-07-21
Release date:2010-06-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structure of the NLRP7 pyrin domain: insight into pyrin-pyrin-mediated effector domain signaling in innate immunity.
J.Biol.Chem., 285, 2010
1I3O
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CRYSTAL STRUCTURE OF THE COMPLEX OF XIAP-BIR2 AND CASPASE 3
Descriptor:CASPASE 3, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, ZINC ION
Authors:Riedl, S.J., Renatus, M., Schwarzenbacher, R., Zhou, Q., Sun, C., Fesik, S.W., Liddington, R.C., Salvesen, G.S.
Deposit date:2001-02-15
Release date:2001-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the inhibition of caspase-3 by XIAP.
Cell(Cambridge,Mass.), 104, 2001
1J7N
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ANTHRAX TOXIN LETHAL FACTOR
Descriptor:Lethal Factor precursor, SULFATE ION, ZINC ION
Authors:Pannifer, A.D., Wong, T.Y., Schwarzenbacher, R., Renatus, M., Petosa, C., Collier, R.J., Bienkowska, J., Lacy, D.B., Park, S., Leppla, S.H., Hanna, P., Liddington, R.C.
Deposit date:2001-05-17
Release date:2001-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1JKY
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CRYSTAL STRUCTURE OF THE ANTHRAX LETHAL FACTOR (LF): WILD-TYPE LF COMPLEXED WITH THE N-TERMINAL SEQUENCE OF MAPKK2
Descriptor:Lethal Factor, mitogen-activated protein kinase kinase 2
Authors:Pannifer, A.D., Wong, T.Y., Schwarzenbacher, R., Renatus, M., Petosa, C., Collier, R.J., Bienkowska, J., Lacy, D.B., Park, S., Leppla, S.H., Hanna, P., Liddington, R.C.
Deposit date:2001-07-13
Release date:2001-11-07
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1OTV
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PQQC, PYRROLOQUINOLINQUINONE SYNTHASE C
Descriptor:Coenzyme PQQ synthesis protein C
Authors:Magnusson, O.T., Toyama, H., Saeki, M., Rojas, A., Reed, J.C., Adachi, O., Klinman, J.P., SChwarzenbacher, R.
Deposit date:2003-03-23
Release date:2004-05-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Quinone Biogenesis: Structure and Mechanism of PqqC, the Final Catalyst in the Production of Pyrroloquinoline Quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
1OTW
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CRYSTAL STRUCTURE OF PQQC IN COMPLEX WITH PQQ AND A PUTATIVE H2O2
Descriptor:Coenzyme PQQ synthesis protein C, PYRROLOQUINOLINE QUINONE, HYDROGEN PEROXIDE
Authors:Magnusson, O.T., Toyama, H., Saeki, M., Rojas, A., Reed, J.C., Liddington, R.C., Klinman, J.P., Schwarzenbacher, R.
Deposit date:2003-03-23
Release date:2004-05-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
1PWQ
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CRYSTAL STRUCTURE OF ANTHRAX LETHAL FACTOR COMPLEXED WITH THIOACETYL-TYR-PRO-MET-AMIDE, A METAL-CHELATING PEPTIDYL SMALL MOLECULE INHIBITOR
Descriptor:Lethal factor, ZINC ION, N-(SULFANYLACETYL)TYROSYLPROLYLMETHIONINAMIDE
Authors:Wong, T.Y., Schwarzenbacher, R., Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1PWU
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CRYSTAL STRUCTURE OF ANTHRAX LETHAL FACTOR COMPLEXED WITH (3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE), A KNOWN SMALL MOLECULE INHIBITOR OF MATRIX METALLOPROTEASES.
Descriptor:Lethal factor, ZINC ION, 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE
Authors:Wong, T.Y., Schwarzenbacher, R., Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1PWV
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CRYSTAL STRUCTURE OF ANTHRAX LETHAL FACTOR WILD-TYPE PROTEIN COMPLEXED WITH AN OPTIMISED PEPTIDE SUBSTRATE.
Descriptor:Lethal factor, LF20
Authors:Wong, T.Y., Schwarzenbacher, R., Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1PWW
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CRYSTAL STRUCTURE OF ANTHRAX LETHAL FACTOR ACTIVE SITE MUTANT PROTEIN COMPLEXED WITH AN OPTIMISED PEPTIDE SUBSTRATE IN THE PRESENCE OF ZINC.
Descriptor:Lethal factor, LF20, ZINC ION
Authors:Wong, T.Y., Schwarzenbacher, R., Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1YBI
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CRYSTAL STRUCTURE OF HA33A, A NEUROTOXIN-ASSOCIATED PROTEIN FROM CLOSTRIDIUM BOTULINUM TYPE A
Descriptor:non-toxin haemagglutinin HA34
Authors:Arndt, J.W., Gu, J., Jaroszewski, L., Schwarzenbacher, R., Hanson, M., Lebeda, F.J., Stevens, R.C.
Deposit date:2004-12-20
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Structure of the Neurotoxin-associated Protein HA33/A from Clostridium botulinum Suggests a Reoccurring beta-Trefoil Fold in the Progenitor Toxin Complex.
J.Mol.Biol., 346, 2005
1Z6T
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STRUCTURE OF THE APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 BOUND TO ADP
Descriptor:Apoptotic protease activating factor 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Riedl, S.J., Li, W., Chao, Y., Schwarzenbacher, R., Shi, Y.
Deposit date:2005-03-23
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of the apoptotic protease-activating factor 1 bound to ADP
Nature, 434, 2005
3HLX
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CRYSTAL STRUCTURE OF PQQC ACTIVE SITE MUTANT Y175F IN COMPLEX WITH PQQ
Descriptor:Pyrroloquinoline-quinone synthase, PYRROLOQUINOLINE QUINONE, GLYCEROL, ...
Authors:Puehringer, S., Schwarzenbacher, R.
Deposit date:2009-05-28
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural studies of mutant forms of the PQQ-forming enzyme PqqC in the presence of product and substrate
Proteins, 78, 2010
3HML
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CRYSTAL STRUCTURE OF PQQC ACTIVE SITE MUTANT H154S IN COMPLEX WITH PQQ
Descriptor:Pyrroloquinoline-quinone synthase, PYRROLOQUINOLINE QUINONE
Authors:Puehringer, S., Schwarzenbacher, R.
Deposit date:2009-05-29
Release date:2010-05-12
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural studies of mutant forms of the PQQ-forming enzyme PqqC in the presence of product and substrate
Proteins, 78, 2010
3HNH
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CRYSTAL STRUCTURE OF PQQC ACTIVE SITE MUTANT Y175S,R179S IN COMPLEX WITH A REACTION INTERMEDIATE
Descriptor:Pyrroloquinoline-quinone synthase, (2S,7R,9R)-4,5-dihydroxy-2,3,6,7,8,9-hexahydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid
Authors:Puehringer, S., Schwarzenbacher, R.
Deposit date:2009-05-31
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural studies of mutant forms of the PQQ-forming enzyme PqqC in the presence of product and substrate
Proteins, 78, 2010
3PMC
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CRYSTAL STRUCTURE OF THE SPORULATION INHIBITOR PXO2-61 FROM BACILLUS ANTHRACIS
Descriptor:Uncharacterized protein pXO2-61/BXB0075/GBAA_pXO2_0075, IODIDE ION, CHLORIDE ION
Authors:Stranzl, G.R., Santelli, E., Bankston, L.A., La Clair, C., Bobkov, A., Schwarzenbacher, R., Godzik, A., Perego, M., Grynberg, M., Liddington, R.C.
Deposit date:2010-11-16
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural Insights into Inhibition of Bacillus anthracis Sporulation by a Novel Class of Non-heme Globin Sensor Domains.
J.Biol.Chem., 286, 2011
3PMD
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CRYSTAL STRUCTURE OF THE SPORULATION INHIBITOR PXO1-118 FROM BACILLUS ANTHRACIS
Descriptor:Conserved domain protein, UNDECANOIC ACID, CHLORIDE ION
Authors:Stranzl, G.R., Santelli, E., Bankston, L.A., La Clair, C., Bobkov, A., Schwarzenbacher, R., Godzik, A., Perego, M., Grynberg, M., Liddington, R.C.
Deposit date:2010-11-16
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Insights into Inhibition of Bacillus anthracis Sporulation by a Novel Class of Non-heme Globin Sensor Domains.
J.Biol.Chem., 286, 2011
1O1Y
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CRYSTAL STRUCTURE OF A GLUTAMINE AMIDOTRANSFERASE (TM1158) FROM THERMOTOGA MARITIMA AT 1.70 A RESOLUTION
Descriptor:conserved hypothetical protein TM1158, SULFATE ION
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2003-02-12
Release date:2003-03-11
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 A resolution.
PROTEINS, 54, 2004
1O2D
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CRYSTAL STRUCTURE OF ALCOHOL DEHYDROGENASE, IRON-CONTAINING (TM0920) FROM THERMOTOGA MARITIMA AT 1.30 A RESOLUTION
Descriptor:Alcohol dehydrogenase, iron-containing, FE (III) ION, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2003-02-27
Release date:2003-06-10
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution
Proteins, 54, 2004
1O4S
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CRYSTAL STRUCTURE OF ASPARTATE AMINOTRANSFERASE (TM1255) FROM THERMOTOGA MARITIMA AT 1.90 A RESOLUTION
Descriptor:Aspartate aminotransferase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2003-06-26
Release date:2003-07-08
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution
Proteins, 55, 2004
1O4T
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CRYSTAL STRUCTURE OF A PREDICTED OXALATE DECARBOXYLASE (TM1287) FROM THERMOTOGA MARITIMA AT 1.95 A RESOLUTION
Descriptor:putative oxalate decarboxylase, MANGANESE (II) ION, OXALATE ION
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2003-07-03
Release date:2003-07-15
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution
Proteins, 56, 2004
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