3EZQ
Crystal Structure of the Fas/FADD Death Domain Complex
Summary for 3EZQ
Entry DOI | 10.2210/pdb3ezq/pdb |
Descriptor | Tumor necrosis factor receptor superfamily member 6, Protein FADD, SULFATE ION, ... (5 entities in total) |
Functional Keywords | apoptosis, disc, fas, fadd, membrane, receptor, transmembrane |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Secreted. Isoform 6: Secreted: P25445 |
Total number of polymer chains | 16 |
Total formula weight | 217475.48 |
Authors | Schwarzenbacher, R.,Robinson, H.,Stec, B.,Riedl, S.J. (deposition date: 2008-10-23, release date: 2008-12-23, Last modification date: 2023-12-27) |
Primary citation | Scott, F.L.,Stec, B.,Pop, C.,Dobaczewska, M.K.,Lee, J.J.,Monosov, E.,Robinson, H.,Salvesen, G.S.,Schwarzenbacher, R.,Riedl, S.J. The Fas-FADD death domain complex structure unravels signalling by receptor clustering Nature, 457:1019-1022, 2009 Cited by PubMed: 19118384DOI: 10.1038/nature07606 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.73 Å) |
Structure validation
Download full validation report