3EZQ

Crystal Structure of the Fas/FADD Death Domain Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007165	biological_process	signal transduction
B	0007165	biological_process	signal transduction
C	0007165	biological_process	signal transduction
D	0007165	biological_process	signal transduction
E	0007165	biological_process	signal transduction
F	0007165	biological_process	signal transduction
G	0007165	biological_process	signal transduction
H	0007165	biological_process	signal transduction
I	0007165	biological_process	signal transduction
J	0007165	biological_process	signal transduction
K	0007165	biological_process	signal transduction
L	0007165	biological_process	signal transduction
M	0007165	biological_process	signal transduction
N	0007165	biological_process	signal transduction
O	0007165	biological_process	signal transduction
P	0007165	biological_process	signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 10

Chain	Residue
A	THR241
A	LEU242
A	LYS274

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA B 21

Chain	Residue
B	GLU179

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 7

Chain	Residue
C	THR241
C	LEU242
C	THR270
C	LYS274

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 1

Chain	Residue
E	LEU242
E	THR270
E	LYS274
E	THR241

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 11

Chain	Residue
E	LYS231
G	LYS231

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 G 2

Chain	Residue
G	MET240
G	THR241
G	LEU242
G	THR270
G	LYS274

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA H 20

Chain	Residue
H	GLU179
H	GLN182

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 I 6

Chain	Residue
I	THR241
I	LEU242
I	THR270
I	LYS274

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 J 8

Chain	Residue
J	GLU95
J	ARG184

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA J 19

Chain	Residue
J	GLU179
J	GLN182

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 K 3

Chain	Residue
K	THR241
K	LEU242
K	LYS274

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 K 13

Chain	Residue
K	ASN324
K	ASN326
K	PHE327
K	GLU330

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 M 9

Chain	Residue
M	MET240
M	THR241
M	LEU242
M	LYS274

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 M 12

Chain	Residue
M	LYS316
M	ASN324
M	ASN326
M	PHE327
M	GLU330

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 O 4

Chain	Residue
O	THR241
O	LEU242
O	THR270
O	LYS274

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA P 18

Chain	Residue
P	GLU179

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1344
Details	Domain: {"description":"Death","evidences":[{"source":"PROSITE-ProRule","id":"PRU00064","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	192
Details	Region: {"description":"Interaction with CALM","evidences":[{"source":"PubMed","id":"24914971","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Glycosylation: {"description":"(Microbial infection) N-beta-linked (GlcNAc) arginine","evidences":[{"source":"PubMed","id":"30979585","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23955153","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Glycosylation: {"description":"(Microbial infection) N-beta-linked (GlcNAc) arginine","evidences":[{"source":"PubMed","id":"24025841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28860194","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30979585","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23955153","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6ACI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---