3EZQ

Crystal Structure of the Fas/FADD Death Domain Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007165	biological_process	signal transduction
B	0007165	biological_process	signal transduction
C	0007165	biological_process	signal transduction
D	0007165	biological_process	signal transduction
E	0007165	biological_process	signal transduction
F	0007165	biological_process	signal transduction
G	0007165	biological_process	signal transduction
H	0007165	biological_process	signal transduction
I	0007165	biological_process	signal transduction
J	0007165	biological_process	signal transduction
K	0007165	biological_process	signal transduction
L	0007165	biological_process	signal transduction
M	0007165	biological_process	signal transduction
N	0007165	biological_process	signal transduction
O	0007165	biological_process	signal transduction
P	0007165	biological_process	signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 10

Chain	Residue
A	THR241
A	LEU242
A	LYS274

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA B 21

Chain	Residue
B	GLU179

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 7

Chain	Residue
C	THR241
C	LEU242
C	THR270
C	LYS274

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 1

Chain	Residue
E	LEU242
E	THR270
E	LYS274
E	THR241

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 11

Chain	Residue
E	LYS231
G	LYS231

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 G 2

Chain	Residue
G	MET240
G	THR241
G	LEU242
G	THR270
G	LYS274

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA H 20

Chain	Residue
H	GLU179
H	GLN182

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 I 6

Chain	Residue
I	THR241
I	LEU242
I	THR270
I	LYS274

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 J 8

Chain	Residue
J	GLU95
J	ARG184

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA J 19

Chain	Residue
J	GLU179
J	GLN182

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 K 3

Chain	Residue
K	THR241
K	LEU242
K	LYS274

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 K 13

Chain	Residue
K	ASN324
K	ASN326
K	PHE327
K	GLU330

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 M 9

Chain	Residue
M	MET240
M	THR241
M	LEU242
M	LYS274

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 M 12

Chain	Residue
M	LYS316
M	ASN324
M	ASN326
M	PHE327
M	GLU330

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 O 4

Chain	Residue
O	THR241
O	LEU242
O	THR270
O	LYS274

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA P 18

Chain	Residue
P	GLU179

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:11034606, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B	SER194
D	SER194
F	SER194
H	SER194
J	SER194
L	SER194
N	SER194
P	SER194

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:24025841, ECO:0000269|PubMed:28860194, ECO:0000269|PubMed:30979585, ECO:0000305|PubMed:23955153, ECO:0007744|PDB:6ACI

Chain	Residue	Details
B	ARG117
D	ARG117
F	ARG117
H	ARG117
J	ARG117
L	ARG117
N	ARG117
P	ARG117

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