Author results

3PCQ
  • Download 3pcq
  • View 3pcq
Molmil generated image of 3pcq
FEMTOSECOND X-RAY PROTEIN NANOCRYSTALLOGRAPHY
Descriptor:Photosystem I P700 chlorophyll a apoprotein A1, Photosystem I P700 chlorophyll a apoprotein A2, Photosystem I iron-sulfur center, ...
Authors:Chapman, H.N., Fromme, P., Barty, A., White, T.A., Kirian, R.A., Aquila, A., Hunter, M.S., Schulz, J., Deponte, D.P., Weierstall, U., Doak, R.B., Maia, F.R.N.C., Martin, A.V., Schlichting, I., Lomb, L., Coppola, N., Shoeman, R.L., Epp, S.W., Hartmann, R., Rolles, D., Rudenko, A., Foucar, L., Kimmel, N., Weidenspointner, G., Holl, P., Liang, M., Barthelmess, M., Caleman, C., Boutet, S., Bogan, M.J., Krzywinski, J., Bostedt, C., Bajt, S., Gumprecht, L., Rudek, B., Erk, B., Schmidt, C., Homke, A., Reich, C., Pietschner, D., Struder, L., Hauser, G., Gorke, H., Ullrich, J., Herrmann, S., Schaller, G., Schopper, F., Soltau, H., Kuhnel, K.-U., Messerschmidt, M., Bozek, J.D., Hau-Riege, S.P., Frank, M., Hampton, C.Y., Sierra, R., Starodub, D., Williams, G.J., Hajdu, J., Timneanu, N., Seibert, M.M., Andreasson, J., Rocker, A., Jonsson, O., Svenda, M., Stern, S., Nass, K., Andritschke, R., Schroter, C.-D., Krasniqi, F., Bott, M., Schmidt, K.E., Wang, X., Grotjohann, I., Holton, J.M., Barends, T.R.M., Neutze, R., Marchesini, S., Fromme, R., Schorb, S., Rupp, D., Adolph, M., Gorkhover, T., Andersson, I., Hirsemann, H., Potdevin, G., Graafsma, H., Nilsson, B., Spence, J.C.H.
Deposit date:2010-10-21
Release date:2011-02-02
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (8.984 Å)
Cite:Femtosecond X-ray protein nanocrystallography.
Nature, 470, 2011
4AC5
  • Download 4ac5
  • View 4ac5
Molmil generated image of 4ac5
LIPIDIC SPONGE PHASE CRYSTAL STRUCTURE OF THE BL. VIRIDIS REACTION CENTRE SOLVED USING SERIAL FEMTOSECOND CRYSTALLOGRAPHY
Descriptor:PHOTOSYNTHETIC REACTION CENTER CYTOCHROME C SUBUNIT, REACTION CENTER PROTEIN H CHAIN, REACTION CENTER PROTEIN L CHAIN, ...
Authors:Johansson, L.C., Arnlund, D., White, T.A., Katona, G., DePonte, D.P., Weierstall, U., Doak, R.B., Shoeman, R.L., Lomb, L., Malmerberg, E., Davidsson, J., Nass, K., Liang, M., Andreasson, J., Aquila, A., Bajt, S., Barthelmess, M., Barty, A., Bogan, M.J., Bostedt, C., Bozek, J.D., Caleman, C., Coffee, R., Coppola, N., Ekeberg, T., Epp, S.W., Erk, B., Fleckenstein, H., Foucar, L., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C.Y., Hartmann, R., Hartmann, A., Hauser, G., Hirsemann, H., Holl, P., Hunter, M.S., Kassemeyer, S., Kimmel, N., Kirian, R.A., Maia, F.R.N.C., Marchesini, S., Martin, A.V., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schlichting, I., Schulz, J., Seibert, M.M., Sierra, R., Soltau, H., Starodub, D., Stellato, F., Stern, S., Struder, L., Timneanu, N., Ullrich, J., Wahlgren, W.Y., Wang, X., Weidenspointner, G., Wunderer, C., Fromme, P., Chapman, H.N., Spence, J.C.H., Neutze, R.
Deposit date:2011-12-14
Release date:2012-02-15
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (8.2 Å)
Cite:Lipidic Phase Membrane Protein Serial Femtosecond Crystallography.
Nat.Methods, 9, 2012
2KO2
  • Download 2ko2
  • View 2ko2
Molmil generated image of 2ko2
NOGO66
Descriptor:Reticulon-4
Authors:Cocco, M.J., Schulz, J., Vasudevan, S.V.
Deposit date:2009-09-08
Release date:2010-04-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Protein folding at the membrane interface, the structure of Nogo-66 requires interactions with a phosphocholine surface.
Proc.Natl.Acad.Sci.USA, 107, 2010
4BGH
  • Download 4bgh
  • View 4bgh
Molmil generated image of 4bgh
CRYSTAL STRUCTURE OF CDK2 IN COMPLEX WITH PAN-CDK INHIBITOR
Descriptor:CYCLIN-DEPENDENT KINASE 2, 4-((5-BROMO-4-(PROP-2-YN-1-YLAMINO)PYRIMIDIN-2-YL)AMINO)BENZENESULFONAMIDE
Authors:Luecking, U., Jautelat, R., Krueger, M., Brumby, T., Lienau, P., Schaefer, M., Briem, H., Schulze, J., Hillisch, A., Reichel, A., Siemeister, G.
Deposit date:2013-03-26
Release date:2013-09-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Lab Oddity Prevails: Discovery of Pan-Cdk Inhibitor (R)- S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-Hydroxy-1-Methylpropyl]Oxy}-5-(Trifluoromethyl)Pyrimidin-2-Yl]Amino}Phenyl)Sulfoximide (Bay 1000394) for the Treatment of Cancer.
Chemmedchem, 8, 2013
5AHV
  • Download 5ahv
  • View 5ahv
Molmil generated image of 5ahv
CRYO-EM STRUCTURE OF HELICAL ANTH AND ENTH TUBULES ON PI(4,5)P2-CONTAINING MEMBRANES
Descriptor:ENTH DOMAIN OF EPSIN ENT1, ANTH DOMAIN OF ENDOCYTIC ADAPTOR SLA2
Authors:Skruzny, M., Desfosses, A., Prinz, S., Dodonova, S.O., Gieras, A., Uetrecht, C., Jakobi, A.J., Abella, M., Hagen, W.J.H., Schulz, J., Meijers, R., Rybin, V., Briggs, J.A.G., Sachse, C., Kaksonen, M.
Deposit date:2015-02-10
Release date:2015-05-06
Last modified:2017-08-09
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:An Organized Co-Assembly of Clathrin Adaptors is Essential for Endocytosis.
Dev.Cell, 33, 2015
6FTR
  • Download 6ftr
  • View 6ftr
Molmil generated image of 6ftr
SERIAL FEMTOSECOND CRYSTALLOGRAPHY AT MEGAHERTZ PULSE RATES
Descriptor:Lysozyme C, CHLORIDE ION, SODIUM ION, ...
Authors:Wiedorn, M.O., Oberthuer, D., Barty, A., Chapman, H.N.
Deposit date:2018-02-23
Release date:2018-10-10
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.760001 Å)
Cite:Megahertz serial crystallography.
Nat Commun, 9, 2018
6GTH
  • Download 6gth
  • View 6gth
Molmil generated image of 6gth
SERIAL FEMTOSECOND CRYSTALLOGRAPHY AT MEGAHERTZ PULSE RATES
Descriptor:Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide
Authors:Wiedorn, M., Oberthuer, D., Werner, N., Schubert, R., White, T.A., Mancuso, A., Perbandt, M., Betzel, C., Barty, A., Chapman, H.
Deposit date:2018-06-18
Release date:2018-10-10
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Megahertz serial crystallography.
Nat Commun, 9, 2018
3GK9
  • Download 3gk9
  • View 3gk9
Molmil generated image of 3gk9
CRYSTAL STRUCTURE OF MURINE NGB UNDER XE PRESSURE
Descriptor:Neuroglobin, XENON, SULFATE ION, ...
Authors:Moschetti, T., Mueller, U., Schultze, J., Brunori, M., Vallone, B.
Deposit date:2009-03-10
Release date:2009-09-22
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of neuroglobin at high Xe and Kr pressure reveals partial conservation of globin internal cavities.
Biophys. J., 97, 2009
3GKT
  • Download 3gkt
  • View 3gkt
Molmil generated image of 3gkt
CRYSTAL STRUCTURE OF MURINE NEUROGLOBIN UNDER KR PRESSURE
Descriptor:Neuroglobin, SULFATE ION, KRYPTON, ...
Authors:Moschetti, T., Mueller, U., Schultze, J., Brunori, M., Vallone, B.
Deposit date:2009-03-11
Release date:2009-09-22
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The structure of neuroglobin at high Xe and Kr pressure reveals partial conservation of globin internal cavities.
Biophys. J., 97, 2009
3GLN
  • Download 3gln
  • View 3gln
Molmil generated image of 3gln
CARBONMONOXY NGB UNDER XENON PRESSURE
Descriptor:Neuroglobin, SULFATE ION, XENON, ...
Authors:Moschetti, T., Mueller, U., Schultze, J., Brunori, M., Vallone, B.
Deposit date:2009-03-12
Release date:2009-09-22
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The structure of neuroglobin at high Xe and Kr pressure reveals partial conservation of globin internal cavities.
Biophys. J., 97, 2009
3MOR
  • Download 3mor
  • View 3mor
Molmil generated image of 3mor
CRYSTAL STRUCTURE OF CATHEPSIN B FROM TRYPANOSOMA BRUCEI
Descriptor:Cathepsin B-like cysteine protease, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Cupelli, K., Stehle, T.
Deposit date:2010-04-23
Release date:2011-11-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:In vivo protein crystallization opens new routes in structural biology.
Nat.Methods, 9, 2012
5K8Y
  • Download 5k8y
  • View 5k8y
Molmil generated image of 5k8y
STRUCTURE OF THE MUS MUSCLUS LANGERIN CARBOHYDRATE RECOGNITION DOMAIN
Descriptor:C-type lectin domain family 4 member K, CALCIUM ION, HEXAETHYLENE GLYCOL, ...
Authors:Loll, B., Aretz, J., Rademacher, C., Wahl, M.C.
Deposit date:2016-05-31
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent.
J. Biol. Chem., 292, 2017
5M62
  • Download 5m62
  • View 5m62
Molmil generated image of 5m62
STRUCTURE OF THE MUS MUSCLUS LANGERIN CARBOHYDRATE RECOGNITION DOMAIN IN COMPLEX WITH GLUCOSE
Descriptor:C-type lectin domain family 4 member K, CALCIUM ION, GLYCEROL, ...
Authors:Loll, B., Aretz, J., Rademacher, C., Wahl, M.C.
Deposit date:2016-10-24
Release date:2016-12-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent.
J. Biol. Chem., 292, 2017
6U57
  • Download 6u57
  • View 6u57
Molmil generated image of 6u57
KDO8PS STRUCTURE DETERMINED AT THE EUXFEL USING SEGMENTED FLOW INJECTION
Descriptor:2-dehydro-3-deoxyphosphooctonate aldolase
Authors:Botha, S., Ros, A.
Deposit date:2019-08-27
Release date:2020-09-02
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Segmented flow generator for serial crystallography at the European X-ray free electron laser.
Nat Commun, 11, 2020
6B36
  • Download 6b36
  • View 6b36
Molmil generated image of 6b36
CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH (S)-N-(3-FLUORO-2-(2-(1-(PHENYLSULFONYL)PIPERAZIN-2-YL)ETHYL)PHENYL)-3,3-BIS(4-FLUOROPHENYL)PROPANAMIDE
Descriptor:HIV-1 Protease, CHLORIDE ION, (S)-N-(3-fluoro-2-(2-(1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
6B38
  • Download 6b38
  • View 6b38
Molmil generated image of 6b38
CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH N-(3-FLUORO-2-(2-((2S,6R)-6-METHYL-1-(PHENYLSULFONYL)PIPERAZIN-2-YL)ETHYL)PHENYL)-3,3-BIS(4-FLUOROPHENYL)PROPANAMIDE
Descriptor:HIV-1 Protease, CHLORIDE ION, N-(3-fluoro-2-{2-[(2S,6R)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl]ethyl}phenyl)-3,3-bis(4-fluorophenyl)propanamide
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
6B3C
  • Download 6b3c
  • View 6b3c
Molmil generated image of 6b3c
CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH N-(3-FLUORO-2-(2-((2S,6R)-6-METHYL-1-(PHENYLSULFONYL)PIPERAZIN-2-YL)ETHYL)PHENYL)-3,3-BIS(4-FLUOROPHENYL)PROPANAMIDE
Descriptor:HIV-1 Protease, CHLORIDE ION, N-(3-fluoro-2-{2-[(2S,5R)-5-methyl-1-(phenylsulfonyl)piperazin-2-yl]ethyl}phenyl)-3,3-bis(4-fluorophenyl)propanamide
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
6B3F
  • Download 6b3f
  • View 6b3f
Molmil generated image of 6b3f
CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH N-(3-FLUORO-2-(2-((2S,5S)-5-METHYL-1-(PHENYLSULFONYL)PIPERAZIN-2-YL)ETHYL)PHENYL)-3,3-BIS(4-FLUOROPHENYL)PROPANAMIDE
Descriptor:HIV-1 Protease, CHLORIDE ION, N-(3-fluoro-2-{2-[(2S,5S)-5-methyl-1-(phenylsulfonyl)piperazin-2-yl]ethyl}phenyl)-3,3-bis(4-fluorophenyl)propanamide
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
6B3G
  • Download 6b3g
  • View 6b3g
Molmil generated image of 6b3g
CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH N-(3-FLUORO-2-(2-((2S,6S)-6-METHYL-1-(PHENYLSULFONYL)PIPERAZIN-2-YL)ETHYL)PHENYL)-3,3-BIS(4-FLUOROPHENYL)PROPANAMIDE
Descriptor:HIV-1 Protease, CHLORIDE ION, N-(3-fluoro-2-{2-[(2S,6S)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl]ethyl}phenyl)-3,3-bis(4-fluorophenyl)propanamide
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
6B3H
  • Download 6b3h
  • View 6b3h
Molmil generated image of 6b3h
CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH N-(2-(2-((6R,9S)-2,2-DIOXIDO-2-THIA-1,7-DIAZABICYCLO[4.3.1]DECAN-9-YL)ETHYL)-3-FLUOROPHENYL)-3,3-BIS(4-FLUOROPHENYL)PROPANAMIDE
Descriptor:HIV-1 Protease, N-(2-{2-[(6R,9S)-2,2-dioxo-2lambda~6~-thia-1,7-diazabicyclo[4.3.1]decan-9-yl]ethyl}-3-fluorophenyl)-3,3-bis(4-fluorophenyl)propanamide, CHLORIDE ION
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
4FE1
  • Download 4fe1
  • View 4fe1
Molmil generated image of 4fe1
IMPROVING THE ACCURACY OF MACROMOLECULAR STRUCTURE REFINEMENT AT 7 A RESOLUTION
Descriptor:Photosystem I P700 chlorophyll a apoprotein A1, Photosystem I P700 chlorophyll a apoprotein A2, Photosystem I iron-sulfur center, ...
Authors:Fromme, R., Adams, P.D., Fromme, P., Levitt, M., Schroeder, G.F., Brunger, A.T.
Deposit date:2012-05-29
Release date:2012-08-15
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (4.9228 Å)
Cite:Improving the accuracy of macromolecular structure refinement at 7 A resolution.
Structure, 20, 2012
169117
PDB entries from 2020-09-23