1US0 | | HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594 AT 0.66 ANGSTROM | | Descriptor: | ALDOSE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, IDD594, ... | | Authors: | Howard, E.I., Sanishvili, R., Cachau, R.E., Mitschler, A., Chevrier, B., Barth, P., Lamour, V., Van Zandt, M., Sibley, E., Bon, C., Moras, D., Schneider, T.R., Joachimiak, A., Podjarny, A. | | Deposit date: | 2003-11-16 | | Release date: | 2004-05-07 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (0.66 Å) | | Cite: | Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A.
Proteins, 55, 2004
|
|
2J8T | | HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP AND CITRATE AT 0.82 ANGSTROM | | Descriptor: | ALDO-KETO REDUCTASE FAMILY 1, MEMBER B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Biadene, M., Hazemann, I., Cousido, A., Ginell, S., Sheldrick, G.M., Podjarny, A., Schneider, T.R. | | Deposit date: | 2006-10-27 | | Release date: | 2007-05-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (0.82 Å) | | Cite: | The Atomic Resolution Structure of Human Aldose Reductase Reveals that Rearrangement of a Bound Ligand Allows the Opening of the Safety-Belt Loop.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
1PWM | | CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP AND FIDARESTAT | | Descriptor: | aldose reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | El-Kabbani, O., Darmanin, C., Schneider, T.R., Hazemann, I., Ruiz, F., Oka, M., Joachimiak, A., Schulze-Briese, C., Tomizaki, T., Mitschler, A., Podjarny, A. | | Deposit date: | 2003-07-02 | | Release date: | 2004-02-24 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (0.92 Å) | | Cite: | Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors
PROTEINS, 55, 2004
|
|
3LZT | | REFINEMENT OF TRICLINIC LYSOZYME AT ATOMIC RESOLUTION | | Descriptor: | LYSOZYME, NITRATE ION, ACETATE ION | | Authors: | Walsh, M.A., Schneider, T., Sieker, L.C., Dauter, Z., Lamzin, V., Wilson, K.S. | | Deposit date: | 1997-03-23 | | Release date: | 1998-03-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (0.925 Å) | | Cite: | Refinement of triclinic hen egg-white lysozyme at atomic resolution.
Acta Crystallogr.,Sect.D, 54, 1998
|
|
1OK0 | | CRYSTAL STRUCTURE OF TENDAMISTAT | | Descriptor: | ALPHA-AMYLASE INHIBITOR HOE-467A, GLYCEROL, CHLORIDE ION | | Authors: | Koenig, V., Vertesy, L., Schneider, T.R. | | Deposit date: | 2003-07-16 | | Release date: | 2004-01-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (0.93 Å) | | Cite: | Crystal Structure of the Alpha-Amylase Inhibitor Tendamistat at 0.93 A
Acta Crystallogr.,Sect.D, 59, 2003
|
|
4LZT | | ATOMIC RESOLUTION REFINEMENT OF TRICLINIC HEW LYSOZYME AT 295K | | Descriptor: | LYSOZYME, NITRATE ION | | Authors: | Walsh, M.A., Schneider, T., Sieker, L.C., Dauter, Z., Lamzin, V., Wilson, K.S. | | Deposit date: | 1997-03-31 | | Release date: | 1998-04-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Refinement of triclinic hen egg-white lysozyme at atomic resolution.
Acta Crystallogr.,Sect.D, 54, 1998
|
|
3SIL | | SIALIDASE FROM SALMONELLA TYPHIMURIUM | | Descriptor: | SIALIDASE, POTASSIUM ION, PHOSPHATE ION, ... | | Authors: | Garman, E.F., Sheldrick, G.M. | | Deposit date: | 1998-07-07 | | Release date: | 1998-11-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | An Enzyme at Atomic Resolution: The 1.05 A Structure of Salmonella Typhimurium Neuraminidase (Sialidase)
To be Published
|
|
1QOW | |
1SHO | | CRYSTAL STRUCTURE OF VANCOMYCIN AT ATOMIC RESOLUTION | | Descriptor: | VANCOMYCIN, BETA-D-GLUCOSE, (1R,3S,4S,5S)-3-amino-2,3,6-trideoxy-3-methyl-alpha-L-arabino-hexopyranose, ... | | Authors: | Sheldrick, G.M. | | Deposit date: | 1997-07-23 | | Release date: | 1997-12-24 | | Last modified: | 2012-12-12 | | Method: | X-RAY DIFFRACTION (1.09 Å) | | Cite: | Crystal Structure of Vancomycin.
Structure, 4, 1996
|
|
1PWL | | CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP AND MINALRESTAT | | Descriptor: | aldose reductase, 2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | El-Kabbani, O., Darmanin, C., Schneider, T.R., Hazemann, I., Ruiz, F., Oka, M., Joachimiak, A., Schulze-Briese, C., Tomizaki, T., Mitschler, A., Podjarny, A. | | Deposit date: | 2003-07-02 | | Release date: | 2004-02-24 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors
PROTEINS, 55, 2004
|
|
1UP9 | | REDUCED STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6 | | Descriptor: | CYTOCHROME C3, HEME C, SULFATE ION | | Authors: | Bento, I., Matias, P.M., Baptista, A.M., Da Costa, P.N., Van Dongen, W.M.A.M., Saraiva, L.M., Schneider, T.R., Soares, C.M., Carrondo, M.A. | | Deposit date: | 2003-09-29 | | Release date: | 2004-09-30 | | Last modified: | 2011-12-28 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6
Proteins, 54, 2004
|
|
1HAZ | | SNAPSHOTS OF SERINE PROTEASE CATALYSIS: (C) ACYL-ENZYME INTERMEDIATE BETWEEN PORCINE PANCREATIC ELASTASE AND HUMAN BETA-CASOMORPHIN-7 JUMPED TO PH 9 FOR 1 MINUTE | | Descriptor: | BETA-CASOMORPHIN-7, ELASTASE 1, CALCIUM ION, ... | | Authors: | Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J. | | Deposit date: | 2001-04-10 | | Release date: | 2001-08-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
|
|
1UPD | | OXIDIZED STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6 | | Descriptor: | CYTOCHROME C3, HEME C | | Authors: | Bento, I., Matias, P.M., Baptista, A.M., Da Costa, P.N., Van Dongen, W.M.A.M., Saraiva, L.M., Schneider, T.R., Soares, C.M., Carrondo, M.A. | | Deposit date: | 2003-09-29 | | Release date: | 2004-09-30 | | Last modified: | 2011-12-28 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6
Proteins, 54, 2004
|
|
1HF4 | | STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS | | Descriptor: | LYSOZYME, SODIUM ION, NITRATE ION | | Authors: | Vaney, M.C., Broutin, I., Ries-Kautt, M., Ducruix, A. | | Deposit date: | 2000-11-29 | | Release date: | 2001-01-07 | | Last modified: | 2019-03-06 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural Effects of Monovalent Anions on Polymorphic Lysozyme Crystals
Acta Crystallogr.,Sect.D, 57, 2001
|
|
5OLT | | CRYSTAL STRUCTURE OF THE EXTRAMEMBRANE DOMAIN OF THE CELLULOSE BIOSYNTHETIC PROTEIN BCSG FROM SALMONELLA TYPHIMURIUM | | Descriptor: | Cellulose biosynthesis protein BcsG, ZINC ION, CITRIC ACID | | Authors: | Vella, P., Polyakova, A., Lindqvist, Y., Schnell, R., Bourenkov, G., Schneider, T., Schneider, G. | | Deposit date: | 2017-07-28 | | Release date: | 2018-08-08 | | Last modified: | 2019-02-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium.
J. Mol. Biol., 430, 2018
|
|
1H9H | | COMPLEX OF EETI-II WITH PORCINE TRYPSIN | | Descriptor: | TRYPSIN, TRYPSIN INHIBITOR II, CALCIUM ION | | Authors: | Kraetzner, R., Wentzel, A., Kolmar, H., Uson, I. | | Deposit date: | 2001-03-12 | | Release date: | 2004-07-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of Ecballium Elaterium Trypsin Inhibitor II (Eeti-II): A Rigid Molecular Scaffold
Acta Crystallogr.,Sect.D, 61, 2005
|
|
1OF8 | | DOUBLE COMPLEX OF THE TYROSINE SENSITIVE DAHP SYNTHASE FROM S. CEREVISIAE WITH CO2+, PEP AND THE E4P ANALOGOUE G3P | | Descriptor: | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED, COBALT (II) ION, ... | | Authors: | Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R. | | Deposit date: | 2003-04-08 | | Release date: | 2004-04-08 | | Last modified: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
J.Mol.Biol., 337, 2004
|
|
1L2H | | CRYSTAL STRUCTURE OF INTERLEUKIN 1-BETA F42W/W120F MUTANT | | Descriptor: | Interleukin 1-beta | | Authors: | Rudolph, M.G., Kelker, M.S., Schneider, T.R., Yeates, T.O., Oseroff, V., Heidary, D.K., Jennings, P.A., Wilson, I.A. | | Deposit date: | 2002-02-21 | | Release date: | 2003-02-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
5OJH | | CRYSTAL STRUCTURE OF THE EXTRAMEMBRANE DOMAIN OF THE CELLULOSE BIOSYNTHETIC PROTEIN BCSG FROM SALMONELLA TYPHIMURIUM | | Descriptor: | Cellulose biosynthesis protein BcsG, ZINC ION, CITRATE ANION | | Authors: | Schneider, G., Vella, P., Lindqvist, Y., Schnell, R. | | Deposit date: | 2017-07-21 | | Release date: | 2018-08-08 | | Last modified: | 2019-02-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium.
J. Mol. Biol., 430, 2018
|
|
1B2K | | STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS | | Descriptor: | PROTEIN (LYSOZYME), IODIDE ION | | Authors: | Vaney, M.C., Broutin, I., Ries-Kautt, M., Ducruix, A. | | Deposit date: | 1998-11-26 | | Release date: | 1998-12-02 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural effects of monovalent anions on polymorphic lysozyme crystals.
Acta Crystallogr.,Sect.D, 57, 2001
|
|
1HAX | | SNAPSHOTS OF SERINE PROTEASE CATALYSIS: (A) ACYL-ENZYME INTERMEDIATE BETWEEN PORCINE PANCREATIC ELASTASE AND HUMAN BETA-CASOMORPHIN-7 AT PH 5 | | Descriptor: | BETA-CASOMORPHIN-7, ELASTASE 1, CALCIUM ION, ... | | Authors: | Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J. | | Deposit date: | 2001-04-10 | | Release date: | 2001-08-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
|
|
1T46 | | STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE | | Descriptor: | Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PHOSPHATE ION, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE | | Authors: | Mol, C.D., Dougan, D.R., Schneider, T.R., Skene, R.J., Kraus, M.L., Scheibe, D.N., Snell, G.P., Zou, H., Sang, B.C., Wilson, K.P. | | Deposit date: | 2004-04-28 | | Release date: | 2004-06-15 | | Last modified: | 2017-08-23 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase.
J.Biol.Chem., 279, 2004
|
|
2BB4 | | PORCINE PANCREATIC ELASTASE COMPLEXED WITH BETA-CASOMORPHIN-7 AND ASP-PHE AT PH 5.0 | | Descriptor: | beta-casomorphin-7, Elastase-1, ASPARTIC ACID, ... | | Authors: | Liu, B., Schofield, C.J., Wilmouth, R.C. | | Deposit date: | 2005-10-17 | | Release date: | 2006-05-30 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
|
|
2BD3 | | PORCINE PANCREATIC ELASTASE COMPLEXED WITH BETA-CASOMORPHIN-7 AND LYS-ALA-NH2 AT PH 5.0 | | Descriptor: | beta-casomorphin-7, Elastase-1, LYSINE, ... | | Authors: | Liu, B., Schofield, C.J., Wilmouth, R.C. | | Deposit date: | 2005-10-20 | | Release date: | 2006-05-30 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
|
|
2BD7 | | PORCINE PANCREATIC ELASTASE COMPLEXED WITH BETA-CASOMORPHIN-7 AND ARG-PHE AT PH 5.0 (50 MIN SOAK) | | Descriptor: | beta-casomorphin-7, Elastase-1, ARGININE, ... | | Authors: | Liu, B., Schofield, C.J., Wilmouth, R.C. | | Deposit date: | 2005-10-20 | | Release date: | 2006-05-30 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
|
|
