Author results

1US0
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HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594 AT 0.66 ANGSTROM
Descriptor:ALDOSE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, IDD594, ...
Authors:Howard, E.I., Sanishvili, R., Cachau, R.E., Mitschler, A., Chevrier, B., Barth, P., Lamour, V., Van Zandt, M., Sibley, E., Bon, C., Moras, D., Schneider, T.R., Joachimiak, A., Podjarny, A.
Deposit date:2003-11-16
Release date:2004-05-07
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (0.66 Å)
Cite:Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A.
Proteins, 55, 2004
2J8T
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HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP AND CITRATE AT 0.82 ANGSTROM
Descriptor:ALDO-KETO REDUCTASE FAMILY 1, MEMBER B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Biadene, M., Hazemann, I., Cousido, A., Ginell, S., Sheldrick, G.M., Podjarny, A., Schneider, T.R.
Deposit date:2006-10-27
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.82 Å)
Cite:The Atomic Resolution Structure of Human Aldose Reductase Reveals that Rearrangement of a Bound Ligand Allows the Opening of the Safety-Belt Loop.
Acta Crystallogr.,Sect.D, 63, 2007
1PWM
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CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP AND FIDARESTAT
Descriptor:aldose reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:El-Kabbani, O., Darmanin, C., Schneider, T.R., Hazemann, I., Ruiz, F., Oka, M., Joachimiak, A., Schulze-Briese, C., Tomizaki, T., Mitschler, A., Podjarny, A.
Deposit date:2003-07-02
Release date:2004-02-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors
PROTEINS, 55, 2004
3LZT
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REFINEMENT OF TRICLINIC LYSOZYME AT ATOMIC RESOLUTION
Descriptor:LYSOZYME, NITRATE ION, ACETATE ION
Authors:Walsh, M.A., Schneider, T., Sieker, L.C., Dauter, Z., Lamzin, V., Wilson, K.S.
Deposit date:1997-03-23
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.925 Å)
Cite:Refinement of triclinic hen egg-white lysozyme at atomic resolution.
Acta Crystallogr.,Sect.D, 54, 1998
1OK0
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CRYSTAL STRUCTURE OF TENDAMISTAT
Descriptor:ALPHA-AMYLASE INHIBITOR HOE-467A, GLYCEROL, CHLORIDE ION
Authors:Koenig, V., Vertesy, L., Schneider, T.R.
Deposit date:2003-07-16
Release date:2004-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:Crystal Structure of the Alpha-Amylase Inhibitor Tendamistat at 0.93 A
Acta Crystallogr.,Sect.D, 59, 2003
4LZT
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ATOMIC RESOLUTION REFINEMENT OF TRICLINIC HEW LYSOZYME AT 295K
Descriptor:LYSOZYME, NITRATE ION
Authors:Walsh, M.A., Schneider, T., Sieker, L.C., Dauter, Z., Lamzin, V., Wilson, K.S.
Deposit date:1997-03-31
Release date:1998-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Refinement of triclinic hen egg-white lysozyme at atomic resolution.
Acta Crystallogr.,Sect.D, 54, 1998
3SIL
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SIALIDASE FROM SALMONELLA TYPHIMURIUM
Descriptor:SIALIDASE, POTASSIUM ION, PHOSPHATE ION, ...
Authors:Garman, E.F., Sheldrick, G.M.
Deposit date:1998-07-07
Release date:1998-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:An Enzyme at Atomic Resolution: The 1.05 A Structure of Salmonella Typhimurium Neuraminidase (Sialidase)
To be Published
1QOW
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MERSACIDIN FROM BACILLUS
Descriptor:MERSACIDIN, METHANOL
Authors:Schneider, T.R., Kaercher, J., Sheldrick, G.M.
Deposit date:1999-11-19
Release date:2000-05-26
Last modified:2012-11-30
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Ab Initio Crystal Structure Determination of the Lantibiotic Mersacidin
Acta Crystallogr.,Sect.D, 56, 2000
1SHO
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CRYSTAL STRUCTURE OF VANCOMYCIN AT ATOMIC RESOLUTION
Descriptor:VANCOMYCIN, BETA-D-GLUCOSE, (1R,3S,4S,5S)-3-amino-2,3,6-trideoxy-3-methyl-alpha-L-arabino-hexopyranose, ...
Authors:Sheldrick, G.M.
Deposit date:1997-07-23
Release date:1997-12-24
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Crystal Structure of Vancomycin.
Structure, 4, 1996
1PWL
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CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP AND MINALRESTAT
Descriptor:aldose reductase, 2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:El-Kabbani, O., Darmanin, C., Schneider, T.R., Hazemann, I., Ruiz, F., Oka, M., Joachimiak, A., Schulze-Briese, C., Tomizaki, T., Mitschler, A., Podjarny, A.
Deposit date:2003-07-02
Release date:2004-02-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors
PROTEINS, 55, 2004
1UP9
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REDUCED STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6
Descriptor:CYTOCHROME C3, HEME C, SULFATE ION
Authors:Bento, I., Matias, P.M., Baptista, A.M., Da Costa, P.N., Van Dongen, W.M.A.M., Saraiva, L.M., Schneider, T.R., Soares, C.M., Carrondo, M.A.
Deposit date:2003-09-29
Release date:2004-09-30
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6
Proteins, 54, 2004
1HAZ
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SNAPSHOTS OF SERINE PROTEASE CATALYSIS: (C) ACYL-ENZYME INTERMEDIATE BETWEEN PORCINE PANCREATIC ELASTASE AND HUMAN BETA-CASOMORPHIN-7 JUMPED TO PH 9 FOR 1 MINUTE
Descriptor:BETA-CASOMORPHIN-7, ELASTASE 1, CALCIUM ION, ...
Authors:Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J.
Deposit date:2001-04-10
Release date:2001-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
1UPD
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OXIDIZED STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6
Descriptor:CYTOCHROME C3, HEME C
Authors:Bento, I., Matias, P.M., Baptista, A.M., Da Costa, P.N., Van Dongen, W.M.A.M., Saraiva, L.M., Schneider, T.R., Soares, C.M., Carrondo, M.A.
Deposit date:2003-09-29
Release date:2004-09-30
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6
Proteins, 54, 2004
1HF4
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STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS
Descriptor:LYSOZYME, SODIUM ION, NITRATE ION
Authors:Vaney, M.C., Broutin, I., Ries-Kautt, M., Ducruix, A.
Deposit date:2000-11-29
Release date:2001-01-07
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Effects of Monovalent Anions on Polymorphic Lysozyme Crystals
Acta Crystallogr.,Sect.D, 57, 2001
5OLT
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CRYSTAL STRUCTURE OF THE EXTRAMEMBRANE DOMAIN OF THE CELLULOSE BIOSYNTHETIC PROTEIN BCSG FROM SALMONELLA TYPHIMURIUM
Descriptor:Cellulose biosynthesis protein BcsG, ZINC ION, CITRIC ACID
Authors:Vella, P., Polyakova, A., Lindqvist, Y., Schnell, R., Bourenkov, G., Schneider, T., Schneider, G.
Deposit date:2017-07-28
Release date:2018-08-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium.
J. Mol. Biol., 430, 2018
1H9H
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COMPLEX OF EETI-II WITH PORCINE TRYPSIN
Descriptor:TRYPSIN, TRYPSIN INHIBITOR II, CALCIUM ION
Authors:Kraetzner, R., Wentzel, A., Kolmar, H., Uson, I.
Deposit date:2001-03-12
Release date:2004-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of Ecballium Elaterium Trypsin Inhibitor II (Eeti-II): A Rigid Molecular Scaffold
Acta Crystallogr.,Sect.D, 61, 2005
1OF8
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DOUBLE COMPLEX OF THE TYROSINE SENSITIVE DAHP SYNTHASE FROM S. CEREVISIAE WITH CO2+, PEP AND THE E4P ANALOGOUE G3P
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED, COBALT (II) ION, ...
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R.
Deposit date:2003-04-08
Release date:2004-04-08
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
J.Mol.Biol., 337, 2004
1L2H
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CRYSTAL STRUCTURE OF INTERLEUKIN 1-BETA F42W/W120F MUTANT
Descriptor:Interleukin 1-beta
Authors:Rudolph, M.G., Kelker, M.S., Schneider, T.R., Yeates, T.O., Oseroff, V., Heidary, D.K., Jennings, P.A., Wilson, I.A.
Deposit date:2002-02-21
Release date:2003-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.
Acta Crystallogr.,Sect.D, 59, 2003
5OJH
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CRYSTAL STRUCTURE OF THE EXTRAMEMBRANE DOMAIN OF THE CELLULOSE BIOSYNTHETIC PROTEIN BCSG FROM SALMONELLA TYPHIMURIUM
Descriptor:Cellulose biosynthesis protein BcsG, ZINC ION, CITRATE ANION
Authors:Schneider, G., Vella, P., Lindqvist, Y., Schnell, R.
Deposit date:2017-07-21
Release date:2018-08-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium.
J. Mol. Biol., 430, 2018
1B2K
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STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS
Descriptor:PROTEIN (LYSOZYME), IODIDE ION
Authors:Vaney, M.C., Broutin, I., Ries-Kautt, M., Ducruix, A.
Deposit date:1998-11-26
Release date:1998-12-02
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural effects of monovalent anions on polymorphic lysozyme crystals.
Acta Crystallogr.,Sect.D, 57, 2001
1HAX
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SNAPSHOTS OF SERINE PROTEASE CATALYSIS: (A) ACYL-ENZYME INTERMEDIATE BETWEEN PORCINE PANCREATIC ELASTASE AND HUMAN BETA-CASOMORPHIN-7 AT PH 5
Descriptor:BETA-CASOMORPHIN-7, ELASTASE 1, CALCIUM ION, ...
Authors:Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J.
Deposit date:2001-04-10
Release date:2001-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
1T46
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STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE
Descriptor:Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PHOSPHATE ION, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
Authors:Mol, C.D., Dougan, D.R., Schneider, T.R., Skene, R.J., Kraus, M.L., Scheibe, D.N., Snell, G.P., Zou, H., Sang, B.C., Wilson, K.P.
Deposit date:2004-04-28
Release date:2004-06-15
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase.
J.Biol.Chem., 279, 2004
2BB4
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PORCINE PANCREATIC ELASTASE COMPLEXED WITH BETA-CASOMORPHIN-7 AND ASP-PHE AT PH 5.0
Descriptor:beta-casomorphin-7, Elastase-1, ASPARTIC ACID, ...
Authors:Liu, B., Schofield, C.J., Wilmouth, R.C.
Deposit date:2005-10-17
Release date:2006-05-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
2BD3
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PORCINE PANCREATIC ELASTASE COMPLEXED WITH BETA-CASOMORPHIN-7 AND LYS-ALA-NH2 AT PH 5.0
Descriptor:beta-casomorphin-7, Elastase-1, LYSINE, ...
Authors:Liu, B., Schofield, C.J., Wilmouth, R.C.
Deposit date:2005-10-20
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
2BD7
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PORCINE PANCREATIC ELASTASE COMPLEXED WITH BETA-CASOMORPHIN-7 AND ARG-PHE AT PH 5.0 (50 MIN SOAK)
Descriptor:beta-casomorphin-7, Elastase-1, ARGININE, ...
Authors:Liu, B., Schofield, C.J., Wilmouth, R.C.
Deposit date:2005-10-20
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006