Author results

6GUA
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XYLULOSE 5-PHOSPHATE PHOSPHOKETOLASE FROM LACTOCOCCUS LACTIS
Descriptor:Probable phosphoketolase, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Scheidig, A.J., Szedlacsek, S.E.
Deposit date:2018-06-19
Release date:2019-05-22
Method:X-RAY DIFFRACTION (1.95 Å), SOLUTION SCATTERING
Cite:Crystal structure of a xylulose 5-phosphate phosphoketolase. insights into the substrate specificity for xylulose 5-phosphate.
J.Struct.Biol., 2019
1CA0
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BOVINE CHYMOTRYPSIN COMPLEXED TO APPI
Descriptor:BOVINE CHYMOTRYPSIN, PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR
Authors:Scheidig, A.J., Kossiakoff, A.A.
Deposit date:1997-01-23
Release date:1997-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci., 6, 1997
821P
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THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLYCINE-12 MUTANT OF P21H-RAS
Descriptor:C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Scheidig, A.J., Krengel, U., Pai, E.F., Kabsch, W., Wittinghofer, A., Goody, R.S.
Deposit date:1993-03-29
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
Biochemistry, 32, 1993
1CBW
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BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI
Descriptor:BOVINE CHYMOTRYPSIN, BPTI, SULFATE ION
Authors:Hynes, T.R., Scheidig, A.J., Kossiakoff, A.A.
Deposit date:1996-12-22
Release date:1997-07-23
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci., 6, 1997
2BMD
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HIGH RESOLUTION STRUCTURE OF GDP-BOUND HUMAN RAB4A
Descriptor:RAS-RELATED PROTEIN RAB4A, GUANOSINE-5'-DIPHOSPHATE, GLYCEROL
Authors:Scheidig, A.J., Huber, S.K.
Deposit date:2005-03-13
Release date:2005-04-25
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High Resolution Crystal Structures of Human Rab4A in its Active and Inactive Conformations.
FEBS Lett., 579, 2005
2BME
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HIGH RESOLUTION STRUCTURE OF GPPNHP-BOUND HUMAN RAB4A
Descriptor:RAS-RELATED PROTEIN RAB4A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Scheidig, A.J., Huber, S.K.
Deposit date:2005-03-13
Release date:2005-04-25
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:High Resolution Crystal Structures of Human Rab4A in its Active and Inactive Conformations.
FEBS Lett., 579, 2005
4PNC
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E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH INHIBITOR 7-METHOXY-2-METHYLEN-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE
Descriptor:Methionine aminopeptidase, (2S)-7-methoxy-2-methyl-3,4-dihydronaphthalen-1(2H)-one, COBALT (II) ION, ...
Authors:Scheidig, A.J., Altmeyer, M., Klein, C.D.
Deposit date:2014-05-23
Release date:2014-07-23
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases.
Bioorg.Med.Chem.Lett., 24, 2014
4W8G
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CRYSTAL STRUCTURE OF THE TIR DOMAIN OF THE TOLL-RELATED RECEPTOR TRR-2 FROM THE LOWER METAZOAN HYDRA MAGNIPAPILLATA (CRYSTAL FORM I)
Descriptor:Toll-receptor-related 2
Authors:Weisse, R.H.-J., Scheidig, A.J.
Deposit date:2014-08-24
Release date:2015-09-09
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the TIR domain of the Toll-related Receptor TRR-2 from the lower metazoan Hydra magnipapillata (crystal form I)
To Be Published
5OJG
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CRYSTAL STRUCTURE OF THE DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 4 (DHRS4) FROM CAENORHABDITIS ELEGANS
Descriptor:Dehydrogenase/reductase SDR family member 4, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, butane-2,3-dione
Authors:Scheidig, A.J., Faust, A., Ebert, B., Maser, E., Kisiela, M.
Deposit date:2017-07-21
Release date:2017-11-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans.
FEBS J., 285, 2018
5OJI
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CRYSTAL STRUCTURE OF THE DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 4 (DHRS4) FROM CAENORHABDITIS ELEGANS
Descriptor:Dehydrogenase/reductase SDR family member 4, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISATIN
Authors:Scheidig, A.J., Faust, A., Ebert, B., Maser, E., Kisiela, M.
Deposit date:2017-07-21
Release date:2017-11-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans.
FEBS J., 285, 2018
2IBS
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CRYSTAL STRUCTURE OF THE ADENINE-SPECIFIC DNA METHYLTRANSFERASE M.TAQI COMPLEXED WITH THE COFACTOR ANALOG AETA AND A 10 BP DNA CONTAINING 2-AMINOPURINE AT THE TARGET POSITION
Descriptor:5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ...
Authors:Pljevaljcic, G., Lenz, T., Scheidig, A.J., Weinhold, E.
Deposit date:2006-09-12
Release date:2007-05-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence
J.Am.Chem.Soc., 129, 2007
2IBT
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CRYSTAL STRUCTURE OF THE ADENINE-SPECIFIC DNA METHYLTRANSFERASE M.TAQI COMPLEXED WITH THE COFACTOR ANALOG AETA AND A 10 BP DNA CONTAINING 2-AMINOPURINE AT THE TARGET POSITION AND AN ABASIC SITE ANALOG AT THE TARGET BASE PARTNER POSITION
Descriptor:5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*(3DR)P*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ...
Authors:Lenz, T., Scheidig, A.J., Weinhold, E.
Deposit date:2006-09-12
Release date:2007-05-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence
J.Am.Chem.Soc., 129, 2007
2IH2
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CRYSTAL STRUCTURE OF THE ADENINE-SPECIFIC DNA METHYLTRANSFERASE M.TAQI COMPLEXED WITH THE COFACTOR ANALOG AETA AND A 10 BP DNA CONTAINING 5-METHYLPYRIMIDIN-2(1H)-ONE AT THE TARGET BASE PARTNER POSITION
Descriptor:5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*(5PY)P*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ...
Authors:Lenz, T., Scheidig, A.J., Weinhold, E.
Deposit date:2006-09-25
Release date:2007-11-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Influence of the target base partner on the methylation rate of the adenine-specific DNA methyltransferase M.TaqI
To be Published
2IH4
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CRYSTAL STRUCTURE OF THE ADENINE-SPECIFIC DNA METHYLTRANSFERASE M.TAQI COMPLEXED WITH THE COFACTOR ANALOG AETA AND A 10 BP DNA CONTAINING PYRROLO-DC AT THE TARGET BASE PARTNER POSITION
Descriptor:5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*(4PC)P*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ...
Authors:Lenz, T., Scheidig, A.J., Weinhold, E.
Deposit date:2006-09-25
Release date:2007-11-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Influence of the target base partner on the methylation rate of the adenine-specific DNA methyltransferase M.TaqI
To be Published
2IH5
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CRYSTAL STRUCTURE OF THE ADENINE-SPECIFIC DNA METHYLTRANSFERASE M.TAQI COMPLEXED WITH THE COFACTOR ANALOG AETA AND A 10 BP DNA CONTAINING AN ABASIC SITE ANALOG AT THE TARGET BASE PARTNER POSITION
Descriptor:5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*(3DR)P*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ...
Authors:Lenz, T., Scheidig, A.J., Weinhold, E.
Deposit date:2006-09-25
Release date:2007-11-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Influence of the target base partner on the methylation rate of the adenine-specific DNA methyltransferase M.TaqI
To be Published
2JG3
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MTAQI WITH BAZ
Descriptor:MODIFICATION METHYLASE TAQI, 5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*AP*TP*CP*GP*6MAP*AP*CP)-3', ...
Authors:Pljevaljcic, G., Scheidig, A.J., Weinhold, E.
Deposit date:2007-02-07
Release date:2007-08-07
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Quantitative Labeling of Long Plasmid DNA with Nanometer Precision.
Chembiochem, 8, 2007
2NP6
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CRYSTAL STRUCTURE OF THE ADENINE-SPECIFIC DNA METHYLTRANSFERASE M.TAQI COMPLEXED WITH THE COFACTOR ANALOG AETA AND A 10 BP DNA CONTAINING AN ABASIC SITE ANALOG AT THE TARGET POSITION
Descriptor:5'-D(*GP*TP*TP*CP*GP*(3DR)P*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ...
Authors:Lenz, T., Scheidig, A.J., Weinhold, E.
Deposit date:2006-10-26
Release date:2007-11-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Caught in the act II: Visualization of an intermediate in the DNA base-flipping pathway induced by the adenine-specific DNA methyltransferase M.TaqI
To be Published
2NP7
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CRYSTAL STRUCTURE OF THE ADENINE-SPECIFIC DNA METHYLTRANSFERASE M.TAQI COMPLEXED WITH THE COFACTOR ANALOG AETA AND A 10 BP DNA CONTAINING AN ABASIC SITE ANALOG AT THE TARGET POSITION AND PYRROLO-DC AT THE TARGET BASE PARTNER POSITION
Descriptor:5'-D(*GP*TP*TP*CP*GP*(3DR)P*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*(4PC)P*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ...
Authors:Lenz, T., Scheidig, A.J., Weinhold, E.
Deposit date:2006-10-26
Release date:2007-11-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Caught in the act II: Visualization of an intermediate in the DNA base-flipping pathway induced by the adenine-specific DNA methyltransferase M.TaqI
To be Published
1AGP
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THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLY-12 MUTANT OF P21-H-RAS
Descriptor:C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Franken, S.M., Scheidig, A.J., Wittinghofer, A., Goody, R.S.
Deposit date:1993-03-29
Release date:1994-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
Biochemistry, 32, 1993
1EK0
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GPPNHP-BOUND YPT51 AT 1.48 A RESOLUTION
Descriptor:PROTEIN (GTP-BINDING PROTEIN YPT51), MAGNESIUM ION, NICKEL (II) ION, ...
Authors:Esters, H., Scheidig, A.J.
Deposit date:2000-03-06
Release date:2000-04-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:High-resolution crystal structure of S. cerevisiae Ypt51(DeltaC15)-GppNHp, a small GTP-binding protein involved in regulation of endocytosis.
J.Mol.Biol., 298, 2000
1FKM
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CRYSTAL STRUCTURE OF THE YPT/RAB-GAP DOMAIN OF GYP1P
Descriptor:PROTEIN (GYP1P)
Authors:Rak, A., Fedorov, R., Alexandrov, K., Albert, S., Goody, R.S., Gallwitz, D., Scheidig, A.J.
Deposit date:2000-08-09
Release date:2001-02-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins.
EMBO J., 19, 2000
1G38
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ADENINE-SPECIFIC METHYLTRANSFERASE M. TAQ I/DNA COMPLEX
Descriptor:5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', MODIFICATION METHYLASE TAQI, ...
Authors:Goedecke, K., Pignot, M., Goody, R.S., Scheidig, A.J., Weinhold, E.
Deposit date:2000-10-23
Release date:2001-03-05
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog.
Nat.Struct.Biol., 8, 2001
1JLN
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PROTEIN TYROSINE PHOSPHATASE PTP-SL/BR7
Descriptor:Protein Tyrosine Phosphatase, receptor type, R
Authors:Szedlacsek, S.E., Aricescu, A.R., Fulga, T.A., Renault, L., Scheidig, A.J.
Deposit date:2001-07-16
Release date:2001-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for MAP kinase regulation.
J.Mol.Biol., 311, 2001
1KY2
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GPPNHP-BOUND YPT7P AT 1.6 A RESOLUTION
Descriptor:GTP-BINDING PROTEIN YPT7P, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Constantinescu, A.-T., Rak, A., Scheidig, A.J.
Deposit date:2002-02-02
Release date:2002-06-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases.
Structure, 10, 2002
1KY3
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GDP-BOUND YPT7P AT 1.35 A RESOLUTION
Descriptor:GTP-BINDING PROTEIN YPT7P, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Constantinescu, A.-T., Rak, A., Scheidig, A.J.
Deposit date:2002-02-02
Release date:2002-06-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases.
Structure, 10, 2002