Author results

5FA2
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CRYSTAL STRUCTURE OF 426C.TM4DELTAV1-3 P120
Descriptor:gp120, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2015-12-10
Release date:2016-04-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5FEC
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CRYSTAL STRUCTURE OF 3BNC60 FAB GERMLINE PRECURSOR IN COMPLEX WITH 426C.TM4DELTAV1-3 GP120
Descriptor:germline 3BNC60 heavy chain, germline 3BNC60 light chain, 426c.TM4deltaV1-3 gp120, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2015-12-16
Release date:2016-05-04
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5I9Q
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CRYSTAL STRUCTURE OF 3BNC55 FAB IN COMPLEX WITH 426C.TM4DELTAV1-3 GP120
Descriptor:426c.TM4dV1-3 p120, 3BNC55 Fab heavy chain, 3BNC55 light chain, ...
Authors:Scharf, L., Chen, C., Bjorkman, P.J.
Deposit date:2016-02-20
Release date:2016-05-04
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5IGX
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CRYSTAL STRUCTURE OF NIH45-46 FAB GERMLINE PRECURSOR IN COMPLEX WITH 426C.TM1DELTAV1-3 GP120
Descriptor:426c.TM1deltaV1-3 gp120, germline NIH45-46 Fab heavy chain, germline NIH45-46 light chain, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2016-02-28
Release date:2016-04-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
3OV6
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CD1C IN COMPLEX WITH MPM (MANNOSYL-BETA1-PHOSPHOMYCOKETIDE)
Descriptor:Beta-2-microglobulin, T-cell surface glycoprotein CD1c, T-cell surface glycoprotein CD1b, ...
Authors:Scharf, L., Li, N.S., Hawk, A.J., Garzon, D., Zhang, T., Kazen, A.R., Shah, S., Haddadian, E.J., Saghatelian, A., Faraldo-Gomez, J.D., Meredith, S.C., Piccirilli, J.A., Adams, E.J.
Deposit date:2010-09-15
Release date:2011-01-19
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation
Immunity, 33, 2010
4JDT
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CRYSTAL STRUCTURE OF CHIMERIC GERM-LINE PRECURSOR OF NIH45-46 FAB IN COMPLEX WITH GP120 OF 93TH057 HIV-1
Descriptor:gp120, Fab heavy chain, Fab light chain, ...
Authors:Scharf, L., Diskin, R., Bjorkman, P.J.
Deposit date:2013-02-25
Release date:2013-03-20
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4P9H
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CRYSTAL STRUCTURE OF 8ANC195 FAB IN COMPLEX WITH GP120 OF 93TH057 HIV-1 AND SOLUBLE CD4 D1D2
Descriptor:T-cell surface glycoprotein CD4, Envelope glycoprotein gp160, Fab heavy chain, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2014-04-04
Release date:2014-05-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
4P9M
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CRYSTAL STRUCTURE OF 8ANC195 FAB
Descriptor:8ANC195 light chain, 8ANC195 Fab heavy chain, N-ACETYL-D-GLUCOSAMINE
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2014-04-04
Release date:2014-05-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
5A7X
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NEGATIVE STAIN EM OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195
Descriptor:HIV-1 YU2 GP120, T-CELL SURFACE GLYCOPROTEIN CD4, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, ...
Authors:Scharf, L., Wang, H., Gao, H., Chen, S., McDowall, A., Bjorkman, P.
Deposit date:2015-07-10
Release date:2015-08-05
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Broadly Neutralizing Antibody 8Anc195 Recognizes Closed and Open States of HIV-1 Env.
Cell(Cambridge,Mass.), 162, 2015
5A8H
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CRYO-ET SUBTOMOGRAM AVERAGING OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195
Descriptor:HIV-1 GP120, T-CELL SURFACE GLYCOPROTEIN CD4, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, ...
Authors:Scharf, L., Wang, H., Gao, H., Chen, S., McDowall, A., Bjorkman, P.
Deposit date:2015-07-15
Release date:2015-08-05
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Cell, 162, 2015
5CJX
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CRYSTAL STRUCTURE OF 8ANC195 FAB IN COMPLEX WITH BG505 SOSIP.664 HIV-1 ENV TRIMER
Descriptor:8ANC195 G52K5 heavy chain, IG gamma-1 chain, BG505 Env gp41, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2015-07-15
Release date:2015-09-23
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.584 Å)
Cite:Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Cell, 162, 2015
5F7E
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CRYSTAL STRUCTURE OF GERM-LINE PRECURSOR OF 3BNC60 FAB
Descriptor:Fab heavy chain, Fab light chain
Authors:Sievers, S.A., Scharf, L., Jiang, S., Bjorkman, P.J.
Deposit date:2015-12-08
Release date:2016-04-06
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5UD9
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CRYSTAL STRUCTURE OF 354BG18 FAB
Descriptor:Fab heavy chain, Light chain
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2016-12-23
Release date:2017-02-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
4FQ1
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CRYSTAL STRUCTURE OF PGT121 FAB
Descriptor:Fab heavy chain, Fab light chain, N-ACETYL-D-GLUCOSAMINE
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2012-06-24
Release date:2012-11-14
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FQ2
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CRYSTAL STRUCTURE OF 10-1074 FAB
Descriptor:Fab heavy chain, Fab light chain, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2012-06-24
Release date:2012-11-14
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FQC
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CRYSTAL STRUCTURE OF PGT121 FAB BOUND TO A COMPLEX-TYPE SIALYLATED N-GLYCAN
Descriptor:Fab heavy chain, Fab light chain, BETA-D-MANNOSE, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2012-06-25
Release date:2012-11-14
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FQQ
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CRYSTAL STRUCTURE OF GERMLINE ANTIBODY PGT121-GL FAB
Descriptor:Fab light chain, Fab heavy chain, SODIUM ION
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2012-06-25
Release date:2012-11-14
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
4JDV
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CRYSTAL STRUCTURE OF GERM-LINE PRECURSOR OF NIH45-46 FAB
Descriptor:Fab heavy chain, Fab light chain, SULFATE ION, ...
Authors:Diskin, R., Scharf, L., Bjorkman, P.J.
Deposit date:2013-02-25
Release date:2013-03-20
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
5VVF
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CRYSTAL STRUCTURE OF 354BG1 FAB
Descriptor:354BG1 Heavy Chain, 354BG1 Light Chain, 1,2-ETHANEDIOL
Authors:Scharf, L., Gristick, H.B., Bjorkman, P.J.
Deposit date:2017-05-19
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
4MNG
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STRUCTURE OF THE DP10.7 TCR WITH CD1D-SULFATIDE
Descriptor:Beta-2-microglobulin, Cd1d1 protein, TRA@ protein,TRA@ protein, ...
Authors:Luoma, A.M., Adams, E.J.
Deposit date:2013-09-10
Release date:2013-12-18
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3.0058 Å)
Cite:Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells.
Immunity, 39, 2013
4MNH
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STRUCTURE OF THE DP10.7 TCR
Descriptor:T-cell receptor gamma chain V region PT-gamma-1/2, Human nkt tcr beta chain, Human nkt tcr alpha chain
Authors:Luoma, A.M., Adams, E.J.
Deposit date:2013-09-10
Release date:2013-12-18
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells.
Immunity, 39, 2013
4MQ7
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STRUCTURE OF HUMAN CD1D-SULFATIDE
Descriptor:Antigen-presenting glycoprotein CD1d, Cd1d1 protein, Beta-2-microglobulin, ...
Authors:Luoma, A.M., Adams, E.J.
Deposit date:2013-09-15
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6032 Å)
Cite:Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells.
Immunity, 39, 2013
4NDM
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STRUCTURE OF THE AB18.1 TCR
Descriptor:T-cell gamma protein,T-cell receptor beta-2 chain C region, Human nkt tcr alpha chain
Authors:Luoma, A.M., Adams, E.J.
Deposit date:2013-10-27
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.0065 Å)
Cite:Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells.
Immunity, 39, 2013
5UEL
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CRYSTAL STRUCTURE OF 354NC102 FAB
Descriptor:354NC102 Fab Heavy Chain, 354NC102 Fab Light Chain, SULFATE ION
Authors:Sievers, S.A., Gristick, H.B., Bjorkman, P.J.
Deposit date:2017-01-02
Release date:2017-02-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
5UEM
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CRYSTAL STRUCTURE OF 354NC37 FAB IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057 GP120
Descriptor:clade A/E 93TH057 HIV-1 gp120 core, 354NC37 Fab Heavy Chain, 354NC37 Fab Light Chain, ...
Authors:Sievers, S.A., Gristick, H.B., Bjorkman, P.J.
Deposit date:2017-01-02
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
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