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1BXL
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BU of 1bxl by Molmil
STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: BAK PEPTIDE, BCL-XL
Authors:Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W.
Deposit date:1996-10-16
Release date:1997-10-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
2MJN
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BU of 2mjn by Molmil
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
Descriptor: Nucleolysin TIA-1 isoform p40
Authors:Sattler, M, Wang, I.
Deposit date:2014-01-13
Release date:2014-04-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
Nucleic Acids Res., 42, 2014
8P25
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BU of 8p25 by Molmil
Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box
Descriptor: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1
Authors:Hipp, C, Sattler, M.
Deposit date:2023-05-14
Release date:2023-07-26
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
4UQT
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BU of 4uqt by Molmil
RRM-peptide structure in RES complex
Descriptor: PRE-MRNA-SPLICING FACTOR CWC26, U2 SNRNP COMPONENT IST3
Authors:Tripsianes, K, Friberg, A, Barrandon, C, Seraphin, B, Sattler, M.
Deposit date:2014-06-25
Release date:2014-09-03
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A Novel Protein-Protein Interaction in the Res (Retention and Splicing) Complex.
J.Biol.Chem., 289, 2014
5JU7
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BU of 5ju7 by Molmil
DNA BINDING DOMAIN OF E.COLI CADC
Descriptor: Transcriptional activator CadC, ZINC ION
Authors:Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
Deposit date:2016-05-10
Release date:2017-04-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.
Sci Rep, 7, 2017
8S3G
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BU of 8s3g by Molmil
Atomic structure of truncated worm GdH
Descriptor: Glutamate dehydrogenase
Authors:Mourao, A, Sattler, M, Geerlof, A.
Deposit date:2024-02-20
Release date:2025-03-05
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Atomic structure of truncated worm GdH
To Be Published
6I68
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BU of 6i68 by Molmil
Co-crystal structure of human SPOP MATH domain (M117V) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-15
Release date:2019-05-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
7NDX
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BU of 7ndx by Molmil
Crystal structure of the human HSP40 DNAJB1-CTDs in complex with a peptide of NudC
Descriptor: 1,2-ETHANEDIOL, DnaJ homolog subfamily B member 1, Nuclear migration protein nudC
Authors:Delhommel, F, Zak, K.M, Popowicz, G.M, Sattler, M.
Deposit date:2021-02-02
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.541 Å)
Cite:NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.
Mol.Cell, 82, 2022
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
Descriptor: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
Authors:Kachariya, N, Sattler, M, Keil, P, Strasser, K.
Deposit date:2022-10-04
Release date:2022-11-09
Last modified:2024-06-19
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
2JW6
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BU of 2jw6 by Molmil
Solution structure of the DEAF1 MYND domain
Descriptor: Deformed epidermal autoregulatory factor 1 homolog, ZINC ION
Authors:Spadaccini, R, Perrin, H, Bottomley, M, Ansieu, S, Sattler, M.
Deposit date:2007-10-08
Release date:2007-12-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Retraction notice to "Structure and functional analysis of the MYND domain" [J. Mol. Biol. (2006) 358, 498-508].
J.Mol.Biol., 376, 2008
3DXB
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BU of 3dxb by Molmil
Structure of the UHM domain of Puf60 fused to thioredoxin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM)
Authors:Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M.
Deposit date:2008-07-24
Release date:2008-10-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60.
J.Biol.Chem., 284, 2009
9GAG
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BU of 9gag by Molmil
Human PEX5 TPR domain in complex with PEX14 KIPSWQIPV peptide
Descriptor: Peroxisomal membrane protein PEX14, Peroxisomal targeting signal 1 receptor
Authors:Emmanouilidis, L, Gaussmann, S, Sattler, M.
Deposit date:2024-07-27
Release date:2024-09-11
Method:SOLUTION NMR
Cite:Humain complexn PEX5 TPR domain with PEX14 KIPSWQIPV peptide
To Be Published
2JXC
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BU of 2jxc by Molmil
Structure of the EPS15-EH2 Stonin2 Complex
Descriptor: CALCIUM ION, Epidermal growth factor receptor substrate 15, Stonin-2
Authors:Rumpf, J, Simon, B, Jung, N, Maritzen, T, Haucke, V, Sattler, M, Groemping, Y.
Deposit date:2007-11-12
Release date:2008-01-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.
Embo J., 27, 2008
9I8B
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BU of 9i8b by Molmil
NMR-based model of an A-form 20mer dsRNA
Descriptor: RNA (5'-R(*AP*CP*UP*GP*GP*AP*CP*AP*AP*AP*UP*AP*CP*UP*CP*CP*GP*AP*GP*G)-3'), RNA (5'-R(*CP*CP*UP*CP*GP*GP*AP*GP*UP*AP*UP*UP*UP*GP*UP*CP*CP*AP*GP*U)-3')
Authors:Mueller-Hermes, C, Sattler, M.
Deposit date:2025-02-04
Release date:2025-03-12
Method:SOLUTION NMR
Cite:NMR-based model of an A-form 20mer dsRNA
To Be Published
1FHO
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BU of 1fho by Molmil
Solution Structure of the PH Domain from the C. Elegans Muscle Protein UNC-89
Descriptor: UNC-89
Authors:Blomberg, N, Baraldi, E, Sattler, M, Saraste, M, Nilges, M.
Deposit date:2000-08-02
Release date:2000-10-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of a PH domain from the C. elegans muscle protein UNC-89 suggests a novel function.
Structure Fold.Des., 8, 2000
1D8B
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BU of 1d8b by Molmil
NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE
Descriptor: SGS1 RECQ HELICASE
Authors:Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M.
Deposit date:1999-10-21
Release date:2000-01-10
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Structure Fold.Des., 7, 1999
4EL6
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BU of 4el6 by Molmil
Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs
Descriptor: IL-4-inducing protein
Authors:Mayerhofer, H, Meyer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Sattler, M, Schramm, G, Mueller-Dieckmann, J.
Deposit date:2012-04-10
Release date:2013-04-10
Last modified:2025-05-07
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:A Crystallin Fold in the Interleukin-4-inducing Principle of Schistosoma mansoni Eggs (IPSE/ alpha-1) Mediates IgE Binding for Antigen-independent Basophil Activation.
J.Biol.Chem., 290, 2015
3NC1
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BU of 3nc1 by Molmil
Crystal structure of the CRM1-RanGTP complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
5AGQ
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BU of 5agq by Molmil
Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes
Descriptor: BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A
Authors:Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M.
Deposit date:2015-02-03
Release date:2015-05-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes.
Nucleic Acids Res., 43, 2015
8POI
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BU of 8poi by Molmil
Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine
Descriptor: 4-pyridin-2-yl-1,3-thiazol-2-amine, Survival of motor neuron-related-splicing factor 30
Authors:Borggraefe, J, Gaussmann, S, Sattler, M.
Deposit date:2023-07-04
Release date:2023-08-23
Last modified:2023-08-30
Method:SOLUTION NMR
Cite:Pharmacological perturbation of the phase-separating protein SMNDC1.
Nat Commun, 14, 2023
1T2S
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BU of 1t2s by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2R
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BU of 1t2r by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
8PXX
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BU of 8pxx by Molmil
Structure of the WW domain tandem of PRPF40A in complex with SF1
Descriptor: Pre-mRNA-processing factor 40 homolog A, Splicing factor 1
Authors:Martinez-Lumbreras, S, Sattler, M.
Deposit date:2023-07-24
Release date:2024-04-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
8PXW
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BU of 8pxw by Molmil
Structure of the WW domain tandem of PRPF40A
Descriptor: Pre-mRNA-processing factor 40 homolog A
Authors:Martinez-Lumbreras, S, Sattler, M.
Deposit date:2023-07-24
Release date:2024-04-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
1MHN
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BU of 1mhn by Molmil
High resolution crystal structure of the SMN Tudor domain
Descriptor: Survival motor neuron protein
Authors:Sprangers, R, Groves, M.R, Sinning, I, Sattler, M.
Deposit date:2002-08-20
Release date:2003-03-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High Resolution X-ray and NMR Structures of the SMN Tudor Domain: conformational variation in the binding site for symmetrically dimethylated arginine residues
J.Mol.Biol., 327, 2003

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