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1M5K
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CRYSTAL STRUCTURE OF A HAIRPIN RIBOZYME IN THE CATALYTICALLY-ACTIVE CONFORMATION
Descriptor:RNA INHIBITOR SUBSTRATE, RNA HAIRPIN RIBOZYME, PROTEIN (U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A), ...
Authors:Rupert, P.B., Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1M5O
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TRANSITION STATE STABILIZATION BY A CATALYTIC RNA
Descriptor:RNA SUBSTRATE, RNA HAIRPIN RIBOZYME, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A, ...
Authors:Rupert, P.B., Massey, A.P., Sigurdsson, S.T., Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1M5P
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TRANSITION STATE STABILIZATION BY A CATALYTIC RNA
Descriptor:RNA INHIBITOR SUBSTRATE, RNA HAIRPIN RIBOZYME, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A, ...
Authors:Rupert, P.B., Massey, A., Sigurdsson, S.T., Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1M5V
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TRANSITION STATE STABILIZATION BY A CATALYTIC RNA
Descriptor:RNA INHIBITOR SUBSTRATE, RNA HAIRPIN RIBOZYME, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A, ...
Authors:Rupert, P.B., Massey, A.P., Sigurdsson, S.T., Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1D1L
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CRYSTAL STRUCTURE OF CRO-F58W MUTANT
Descriptor:LAMBDA CRO REPRESSOR, SULFATE ION
Authors:Rupert, P.B., Mollah, A.K., Mossing, M.C., Matthews, B.W.
Deposit date:1999-09-17
Release date:1999-10-06
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structural basis for enhanced stability and reduced DNA binding seen in engineered second-generation Cro monomers and dimers.
J.Mol.Biol., 296, 2000
1D1M
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CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT
Descriptor:LAMBDA CRO REPRESSOR
Authors:Rupert, P.B., Mollah, A.K., Mossing, M.C., Matthews, B.W.
Deposit date:1999-09-17
Release date:1999-09-24
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The structural basis for enhanced stability and reduced DNA binding seen in engineered second-generation Cro monomers and dimers.
J.Mol.Biol., 296, 2000
1NU4
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U1A RNA BINDING DOMAIN AT 1.8 ANGSTROM RESOLUTION REVEALS A PRE-ORGANIZED C-TERMINAL HELIX
Descriptor:U1A RNA binding domain, MAGNESIUM ION, MALONIC ACID
Authors:Rupert, P.B., Xiao, H., Ferre-D'Amare, A.R.
Deposit date:2003-01-30
Release date:2003-02-14
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:U1A RNA-binding domain at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
1SKN
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THE BINDING DOMAIN OF SKN-1 IN COMPLEX WITH DNA: A NEW DNA-BINDING MOTIF
Descriptor:DNA (5'-D(*TP*GP*AP*CP*AP*AP*TP*GP*TP*CP*AP*TP*CP*CP*C)-3'), DNA (5'-D(*CP*AP*GP*GP*GP*AP*TP*GP*AP*CP*AP*TP*TP*GP*T)-3'), DNA-BINDING DOMAIN OF SKN-1, ...
Authors:Rupert, P.B., Daughdrill, G.W., Bowerman, B., Matthews, B.W.
Deposit date:1998-03-30
Release date:1998-06-24
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A new DNA-binding motif in the Skn-1 binding domain-DNA complex.
Nat.Struct.Biol., 5, 1998
5JR8
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DISPOSAL OF IRON BY A MUTANT FORM OF SIDEROCALIN NGAL
Descriptor:Neutrophil gelatinase-associated lipocalin, PHOSPHATE ION, GLYCEROL
Authors:Rupert, P.B., Strong, R.K., Barasch, J., Hollman, M., Deng, R., Hod, E.A., Abergel, R., Allred, B., Xu, K., Darrah, S., Tekabe, Y., Perlstein, A., Bruck, E., Stauber, J., Corbin, K., Buchen, C., Slavkovich, V., Graziano, J., Spitalnik, S., Qiu, A.
Deposit date:2016-05-05
Release date:2016-09-28
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Disposal of iron by a mutant form of lipocalin 2.
Nat Commun, 7, 2016
5KHP
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TIGHTENING THE RECOGNITION OF TETRAVALENT ZR AND TH COMPLEXES BY THE SIDEROPHORE-BINDING MAMMALIAN PROTEIN SIDEROCALIN FOR THERANOSTIC APPLICATIONS
Descriptor:Neutrophil gelatinase-associated lipocalin, ZIRCONIUM ION, N,N'-(butane-1,4-diyl)bis(N-{3-[(2,3-dihydroxybenzene-1-carbonyl)amino]propyl}-2,3-dihydroxybenzamide), ...
Authors:Rupert, P.B., Strong, R.K.
Deposit date:2016-06-15
Release date:2017-04-26
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator-Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms.
Inorg Chem, 55, 2016
5KIC
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LONG-SOUGHT STABILIZATION OF BERKELIUM(IV) IN SOLUTION: AN ANOMALY WITHIN THE HEAVY ACTINIDE SERIES
Descriptor:Neutrophil gelatinase-associated lipocalin, CALIFORNIUM ION, N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide], ...
Authors:Rupert, P.B., Strong, R.K.
Deposit date:2016-06-16
Release date:2017-04-26
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Chelation and stabilization of berkelium in oxidation state +IV.
Nat Chem, 9, 2017
5KID
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TIGHTENING THE RECOGNITION OF TETRAVALENT ZR AND TH COMPLEXES BY THE SIDEROPHORE-BINDING MAMMALIAN PROTEIN SIDEROCALIN FOR THERANOSTIC APPLICATIONS
Descriptor:Neutrophil gelatinase-associated lipocalin, THORIUM ION, N,N'-(butane-1,4-diyl)bis(N-{3-[(2,3-dihydroxybenzene-1-carbonyl)amino]propyl}-2,3-dihydroxybenzamide), ...
Authors:Rupert, P.B., Strong, R.K.
Deposit date:2016-06-16
Release date:2017-04-26
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator-Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms.
Inorg Chem, 55, 2016
6O5D
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PYOCHELIN
Descriptor:Neutrophil gelatinase-associated lipocalin, SULFATE ION, GLYCEROL
Authors:Rupert, P.B., Strong, R.K., Clifton, M.C., Edwards, T.E., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-03-01
Release date:2019-09-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands
J.Struct.Biol., 2019
4LCI
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ANTI CANINE CD28 ANTIBODY, 1C6
Descriptor:anti canine CD28 antibody, 1C6, light chain, ...
Authors:Gewe, M.M., Rupert, P.B., Strong, R.K.
Deposit date:2013-06-21
Release date:2014-06-25
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Anti canine CD28 antibody, 1C6
To be Published
4LLV
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THE STRUCTURE OF THE UNBOUND FORM OF ANTI-HIV ANTIBODY 4E10 FV
Descriptor:4E10 Fv heavy chain, 4E10 Fv light chain, SULFATE ION, ...
Authors:Finton, K.A.K., Rupert, P.B., Strong, R.K.
Deposit date:2013-07-09
Release date:2013-10-16
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10.
Plos Pathog., 9, 2013
4ZFX
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SIDEROCALIN-MEDIATED RECOGNITION AND CELLULAR UPTAKE OF ACTINIDES
Descriptor:Neutrophil gelatinase-associated lipocalin, THORIUM ION, N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide), ...
Authors:Allred, B.E., Rupert, P.B., Gauny, S.S., An, D.D., Ralston, C.Y., Sturzbecher-Hoehne, M., Strong, R.K., Abergel, R.J.
Deposit date:2015-04-22
Release date:2015-08-05
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHC
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SIDEROCALIN-MEDIATED RECOGNITION AND CELLULAR UPTAKE OF ACTINIDES
Descriptor:Neutrophil gelatinase-associated lipocalin, THORIUM ION, N-{2-[bis(2-{[(2,3-dihydroxyphenyl)carbonyl]amino}ethyl)amino]ethyl}-1-hydroxy-6-oxo-1,6-dihydropyridine-2-carboxamide, ...
Authors:Allred, B.E., Rupert, P.B., Gauny, S.S., An, D.D., Ralston, C.Y., Sturzbecher-Hoehne, M., Strong, R.K., Abergel, R.J.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHD
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SIDEROCALIN-MEDIATED RECOGNITION AND CELLULAR UPTAKE OF ACTINIDES
Descriptor:Neutrophil gelatinase-associated lipocalin, PLUTONIUM ION, methyl N-(2,3-dihydroxybenzoyl)-O-formyl-L-serinate, ...
Authors:Allred, B.E., Rupert, P.B., Gauny, S.S., An, D.D., Ralston, C.Y., Sturzbecher-Hoehne, M., Strong, R.K., Abergel, R.J.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHF
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SIDEROCALIN-MEDIATED RECOGNITION AND CELLULAR UPTAKE OF ACTINIDES
Descriptor:Neutrophil gelatinase-associated lipocalin, CURIUM ION, N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide], ...
Authors:Allred, B.E., Rupert, P.B., Gauny, S.S., An, D.D., Ralston, C.Y., Sturzbecher-Hoehne, M., Strong, R.K., Abergel, R.J.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHG
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SIDEROCALIN-MEDIATED RECOGNITION AND CELLULAR UPTAKE OF ACTINIDES
Descriptor:Neutrophil gelatinase-associated lipocalin, AMERICIUM ION, N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide], ...
Authors:Allred, B.E., Rupert, P.B., Gauny, S.S., An, D.D., Ralston, C.Y., Sturzbecher-Hoehne, M., Strong, R.K., Abergel, R.J.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHH
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SIDEROCALIN-MEDIATED RECOGNITION AND CELLULAR UPTAKE OF ACTINIDES
Descriptor:Neutrophil gelatinase-associated lipocalin, SAMARIUM (III) ION, N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide], ...
Authors:Allred, B.E., Rupert, P.B., Gauny, S.S., An, D.D., Ralston, C.Y., Sturzbecher-Hoehne, M., Strong, R.K., Abergel, R.J.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4JLR
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CRYSTAL STRUCTURE OF A DESIGNED RESPIRATORY SYNCYTIAL VIRUS IMMUNOGEN IN COMPLEX WITH MOTAVIZUMAB
Descriptor:Motavizumab Fab heavy chain, Motavizumab Fab light chain, RSV_1Isea designed scaffold, ...
Authors:Rupert, P.B., Correia, B., Schief, W., Strong, R.K.
Deposit date:2013-03-12
Release date:2014-02-05
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Proof of principle for epitope-focused vaccine design.
Nature, 507, 2014
5JG9
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CRYSTAL STRUCTURE OF THE DE NOVO MINI PROTEIN GEHEE_06
Descriptor:de novo design, hyper stable, disulfide-rich mini protein, ...
Authors:Rupert, P.B., Johnsen, W.A.
Deposit date:2016-04-19
Release date:2016-09-28
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Accurate de novo design of hyperstable constrained peptides.
Nature, 538, 2016
6ATL
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EXPLORING CYSTINE DENSE PEPTIDE SPACE TO OPEN A UNIQUE MOLECULAR TOOLBOX
Descriptor:Potassium channel toxin alpha-KTx 4.2, SULFATE ION, CITRIC ACID
Authors:Gewe, M.M., Rupert, P., Strong, R.K.
Deposit date:2017-08-29
Release date:2018-02-28
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Screening, large-scale production and structure-based classification of cystine-dense peptides.
Nat. Struct. Mol. Biol., 25, 2018
6ATN
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EXPLORING CYSTINE DENSE PEPTIDE SPACE TO OPEN A UNIQUE MOLECULAR TOOLBOX
Descriptor:Potassium channel toxin alpha-KTx 4.5
Authors:Gewe, M.M., Rupert, P., Strong, R.K.
Deposit date:2017-08-29
Release date:2018-02-28
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Screening, large-scale production and structure-based classification of cystine-dense peptides.
Nat. Struct. Mol. Biol., 25, 2018
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