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6BCD
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BU of 6bcd by Molmil
Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014)
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BC8
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BU of 6bc8 by Molmil
Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex
Descriptor: ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ...
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BI7
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BU of 6bi7 by Molmil
Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y.
Deposit date:2017-11-01
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2M5S
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BU of 2m5s by Molmil
High-resolution NMR structure and cryo-EM imaging support multiple functional roles for the accessory I-domain of phage P22 coat protein
Descriptor: Coat protein
Authors:Rizzo, A.A, Suhanovsky, M.M, Baker, M.L, Fraser, L.C.R, Jones, L.M, Rempel, D.L, Gross, M.L, Chiu, W, Alexandrescu, A.T, Teschke, C.M.
Deposit date:2013-03-05
Release date:2014-03-05
Last modified:2014-07-02
Method:SOLUTION NMR
Cite:Multiple Functional Roles of the Accessory I-Domain of Bacteriophage P22 Coat Protein Revealed by NMR Structure and CryoEM Modeling.
Structure, 22, 2014
2MRE
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BU of 2mre by Molmil
NMR structure of the Rad18-UBZ/ubiquitin complex
Descriptor: E3 ubiquitin-protein ligase RAD18, Polyubiquitin-C, ZINC ION
Authors:Rizzo, A.A, Salerno, P.E, Bezsonova, I, Korzhnev, D.M.
Deposit date:2014-07-03
Release date:2014-10-22
Last modified:2014-10-29
Method:SOLUTION NMR
Cite:NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response.
Biochemistry, 53, 2014
2MRF
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BU of 2mrf by Molmil
NMR structure of the ubiquitin-binding zinc finger (UBZ) domain from human Rad18
Descriptor: E3 ubiquitin-protein ligase RAD18, ZINC ION
Authors:Rizzo, A.A, Salerno, P.E, Bezsonova, I, Korzhnev, D.M.
Deposit date:2014-07-03
Release date:2014-10-01
Last modified:2014-10-08
Method:SOLUTION NMR
Cite:NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response.
Biochemistry, 53, 2014
6WS5
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BU of 6ws5 by Molmil
Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT
Descriptor: 3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ...
Authors:McPherson, K.S, Korzhnev, D.M.
Deposit date:2020-04-30
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.472 Å)
Cite:Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
6WS0
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BU of 6ws0 by Molmil
Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT
Descriptor: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B
Authors:McPherson, K.S, Korzhnev, D.M.
Deposit date:2020-04-30
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
2N1G
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BU of 2n1g by Molmil
Structure of C-terminal domain of human polymerase Rev1 in complex with PolD3 RIR-motif
Descriptor: DNA polymerase delta subunit 3, DNA repair protein REV1
Authors:Pustovalova, Y, Korzhnev, D.
Deposit date:2015-04-01
Release date:2016-04-13
Last modified:2016-04-20
Method:SOLUTION NMR
Cite:Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Pol zeta Suggests a Mechanism of Polymerase Exchange upon Rev1/Pol zeta-Dependent Translesion Synthesis.
Biochemistry, 55, 2016

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