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3VRS
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CRYSTAL STRUCTURE OF FLUORIDE RIBOSWITCH, SOAKED IN MN2+
Descriptor:Fluoride riboswitch, MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Ren, A.M., Rajashankar, K.R., Patel, D.J.
Deposit date:2012-04-13
Release date:2012-05-09
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
4EN5
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CRYSTAL STRUCTURE OF FLUORIDE RIBOSWITCH, TL-ACETATE SOAKED
Descriptor:Fluoride riboswitch, MAGNESIUM ION, FLUORIDE ION, ...
Authors:Ren, A.M., Rajashankar, K.R., Patel, D.J.
Deposit date:2012-04-12
Release date:2012-05-09
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.957 Å)
Cite:Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
4ENA
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CRYSTAL STRUCTURE OF FLUORIDE RIBOSWITCH, SOAKED IN CS+
Descriptor:Fluoride riboswitch, CESIUM ION, MAGNESIUM ION, ...
Authors:Ren, A.M., Rajashankar, K.R., Patel, D.J.
Deposit date:2012-04-12
Release date:2012-05-09
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
4ENB
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CRYSTAL STRUCTURE OF FLUORIDE RIBOSWITCH, BOUND TO IRIDIUM
Descriptor:Fluoride riboswitch, IRIDIUM HEXAMMINE ION, POTASSIUM ION, ...
Authors:Ren, A.M., Rajashankar, K.R., Patel, D.J.
Deposit date:2012-04-12
Release date:2012-05-09
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
4ENC
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CRYSTAL STRUCTURE OF FLUORIDE RIBOSWITCH
Descriptor:Fluoride riboswitch, MAGNESIUM ION, FLUORIDE ION, ...
Authors:Ren, A.M., Rajashankar, K.R., Patel, D.J.
Deposit date:2012-04-12
Release date:2012-05-09
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.272 Å)
Cite:Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
4IX7
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CRYSTAL STRUCTURE OF THE INSV-BEN DOMAIN COMPLEXED TO ITS DNA TARGET SITE
Descriptor:5'-D(*GP*TP*TP*CP*CP*AP*AP*TP*TP*GP*GP*AP*A)-3', RE55538p
Authors:Ren, A., Serganov, A., Patel, D.J.
Deposit date:2013-01-24
Release date:2013-03-20
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (1.581 Å)
Cite:The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors.
Genes Dev., 27, 2013
4NLD
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CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH BMS-791325 ALSO KNOWN AS (1AR,12BS)-8-CYCLOHEXYL-N-(DIMETHYLSULFAMOYL)-11-METHOXY-1A-{[(1R,5S)-3-METHYL-3,8-DIAZABICYCLO[3.2.1]OCT-8-YL]CARBONYL}-1,1A,2,12B-TETRAHYDROCYCLOPROPA[D]INDOLO[2,1-A][2]BENZAZEPINE-5-CARBOXAMIDE AND 2-(4-FLUOROPHENYL)-N-METHYL-6-[(METHYLSULFONYL)AMINO]-5-(PROPAN-2-YLOXY)-1-BENZOFURAN-3-CARBOXAMIDE
Descriptor:RNA-directed RNA polymerase, (1aR,12bS)-8-cyclohexyl-N-(dimethylsulfamoyl)-11-methoxy-1a-{[(1R,5S)-3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl]carbonyl}-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide, 2-(4-fluorophenyl)-N-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide, ...
Authors:Sheriff, S.
Deposit date:2013-11-14
Release date:2014-03-19
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Discovery and Preclinical Characterization of the Cyclopropylindolobenzazepine BMS-791325, A Potent Allosteric Inhibitor of the Hepatitis C Virus NS5B Polymerase.
J.Med.Chem., 57, 2014
4QLM
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YDAO RIBOSWITCH BINDING TO C-DI-AMP
Descriptor:RNA (108-MER), MAGNESIUM ION, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ...
Authors:Ren, A.M., Patel, D.J.
Deposit date:2014-06-12
Release date:2014-08-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.721 Å)
Cite:c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets.
Nat.Chem.Biol., 10, 2014
4QLN
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STRUCTURE OF YDAO RIBOSWITCH BINDING WITH C-DI-DAMP
Descriptor:RNA (117-MER), (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION
Authors:Ren, A.M., Patel, D.J.
Deposit date:2014-06-12
Release date:2014-08-13
Last modified:2014-09-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets.
Nat.Chem.Biol., 10, 2014
4RGE
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CRYSTAL STRUCTURE OF THE IN-LINE ALIGNED ENV22 TWISTER RIBOZYME
Descriptor:env22 twister ribozyme, MAGNESIUM ION
Authors:Ren, A., Rajashankar, K.R., Simanshu, D., Patel, D.
Deposit date:2014-09-30
Release date:2014-12-03
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
Nat Commun, 5, 2014
4RGF
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CRYSTAL STRUCTURE OF THE IN-LINE ALIGNED ENV22 TWISTER RIBOZYME SOAKED WITH MN2+
Descriptor:env22 twister ribozyme, MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Ren, A., Rajashankar, K.R., Simanshu, D., Patel, D.
Deposit date:2014-09-30
Release date:2014-12-03
Method:X-RAY DIFFRACTION (3.2008 Å)
Cite:In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
Nat Commun, 5, 2014
4X0G
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STRUCTURE OF BSG25A BINDING WITH DNA
Descriptor:Blastoderm-specific gene 25A, DNA (5'-D(*GP*TP*TP*CP*CP*AP*AP*TP*TP*GP*GP*AP*A)-3'), ACETATE ION
Authors:Ren, A.
Deposit date:2014-11-21
Release date:2015-01-21
Method:X-RAY DIFFRACTION (3.2065 Å)
Cite:Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family.
Genes Dev., 29, 2015
4YAZ
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3',3'-CGAMP RIBOSWITCH BOUND WITH 3',3'-CGAMP
Descriptor:RNA (84-MER), MAGNESIUM ION, POTASSIUM ION, ...
Authors:Ren, A.M., Patel, D.J., Rajashankar, R.K.
Deposit date:2015-02-18
Release date:2015-04-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep, 11, 2015
4YB0
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3',3'-CGAMP RIBOSWITCH BOUND WITH C-DI-GMP
Descriptor:RNA (84-MER), GUANOSINE-5'-DIPHOSPHATE, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ...
Authors:Ren, A.M., Patel, D.J., Rajashankar, R.K.
Deposit date:2015-02-18
Release date:2015-04-15
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.121 Å)
Cite:Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep, 11, 2015
4YB1
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20A MUTANT C-DI-GMP VC2 RIBOSWITCH BOUND WITH 3',3'-CGAMP
Descriptor:RNA (91-MER), U1 small nuclear ribonucleoprotein A, MAGNESIUM ION, ...
Authors:Ren, A.M., Patel, D.J., Rajashankar, R.K.
Deposit date:2015-02-18
Release date:2015-04-15
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.081 Å)
Cite:Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep, 11, 2015
4ZNP
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THE STRUCTURE OF A PFI RIBOSWITCH BOUND TO ZMP
Descriptor:pfI Riboswitch, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION
Authors:Ren, A., Patel, D.J., Rajashankar, R.K.
Deposit date:2015-05-05
Release date:2015-08-26
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism.
Structure, 23, 2015
5DDO
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STRUCTURAL AND DYNAMIC BASIS FOR LOW AFFINITY-HIGH SELECTIVITY BINDING OF L-GLUTAMINE BY THE GLN-RIBOSWITCH
Descriptor:L-glutamine riboswitch (58-MER), U1 small nuclear ribonucleoprotein A
Authors:Ren, A., Patel, D.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DDP
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L-GLUTAMINE RIBOSWITCH BOUND WITH L-GLUTAMINE
Descriptor:RNA (61-MER), U1 small nuclear ribonucleoprotein A, GLUTAMINE, ...
Authors:Ren, A., Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DDQ
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L-GLUTAMINE RIBOSWITCH BOUND WITH L-GLUTAMINE SOAKED WITH MN2+
Descriptor:L-glutamine riboswitch RNA (61-MER), U1 small nuclear ribonucleoprotein A, GLUTAMINE, ...
Authors:Ren, A., Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DDR
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L-GLUTAMINE RIBOSWITCH BOUND WITH L-GLUTAMINE SOAKED WITH CS+
Descriptor:L-glutamine riboswitch RNA (61-MER), U1 small nuclear ribonucleoprotein A, GLUTAMINE, ...
Authors:Ren, A., Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DUN
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THE CRYSTAL STRUCTURE OF OME SUBSTITUTED TWISTER RIBOZYME
Descriptor:RNA (54-MER), MAGNESIUM ION, POTASSIUM ION
Authors:Ren, A., Patel, D.J., Micura, R., Rajashankar, K.R.
Deposit date:2015-09-19
Release date:2015-10-28
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class.
Angew.Chem.Int.Ed.Engl., 54, 2015
5K7C
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THE NATIVE STRUCTURE OF NATIVE PISTOL RIBOZYME
Descriptor:RNA 47-MER, DNA/RNA 11-MER, MAGNESIUM ION
Authors:Ren, A., Patel, D.
Deposit date:2016-05-26
Release date:2016-07-13
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5K7D
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THE STRUCTURE OF NATIVE PISTOL RIBOZYME, BOUND TO IRIDIUM
Descriptor:RNA 47-MER, DNA/RNA 11-MER, IRIDIUM HEXAMMINE ION, ...
Authors:Ren, A., Patel, D.
Deposit date:2016-05-26
Release date:2016-07-13
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5K7E
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THE STRUCTURE OF PISTOL RIBOZYME, SOAKED WITH MN2+
Descriptor:RNA 47-MER, DNA/RNA 11-MER, MANGANESE (II) ION
Authors:Ren, A., Patel, D.
Deposit date:2016-05-26
Release date:2016-07-13
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5Y85
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STRUCTURE-BASED INSIGHTS INTO SELF-CLEAVAGE BY A FOUR-WAY JUNCTIONAL TWISTER-SISTER RIBOZYME
Descriptor:RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3'), DNA/RNA (50-MER), MAGNESIUM ION
Authors:Zheng, L., Micura, R.L., Ren, A.
Deposit date:2017-08-18
Release date:2017-11-22
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
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