Author results

1D9K
  • Download 1d9k
  • View 1d9k
Molmil generated image of 1d9k
CRYSTAL STRUCTURE OF COMPLEX BETWEEN D10 TCR AND PMHC I-AK/CA
Descriptor:T-CELL RECEPTOR D10 (ALPHA CHAIN), T-CELL RECEPTOR D10 (BETA CHAIN), MHC I-AK A CHAIN (ALPHA CHAIN), ...
Authors:Reinherz, E.L., Tan, K., Tang, L., Kern, P., Liu, J.-H., Xiong, Y., Hussey, R.E., Smolyar, A., Hare, B., Zhang, R., Joachimiak, A., Chang, H.-C., Wagner, G., Wang, J.-H.
Deposit date:1999-10-28
Release date:1999-12-15
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The crystal structure of a T cell receptor in complex with peptide and MHC class II.
Science, 286, 1999
1JBJ
  • Download 1jbj
  • View 1jbj
Molmil generated image of 1jbj
CD3 EPSILON AND GAMMA ECTODOMAIN FRAGMENT COMPLEX IN SINGLE-CHAIN CONSTRUCT
Descriptor:CD3 Epsilon and gamma Ectodomain Fragment Complex
Authors:Sun, Z.-Y.J., Kim, K.S., Wagner, G., Reinherz, E.L.
Deposit date:2001-06-05
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Mechanisms contributing to T cell receptor signaling and assembly revealed by the solution structure of an ectodomain fragment of the CD3 epsilon gamma heterodimer.
Cell(Cambridge,Mass.), 105, 2001
1NFD
  • Download 1nfd
  • View 1nfd
Molmil generated image of 1nfd
AN ALPHA-BETA T CELL RECEPTOR (TCR) HETERODIMER IN COMPLEX WITH AN ANTI-TCR FAB FRAGMENT DERIVED FROM A MITOGENIC ANTIBODY
Descriptor:N15 ALPHA-BETA T-CELL RECEPTOR, H57 FAB, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, J.-H., Lim, K., Smolyar, A., Teng, M.-K., Sacchittini, J., Reinherz, E.L.
Deposit date:1997-08-04
Release date:1998-01-28
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody.
EMBO J., 17, 1998
1QA9
  • Download 1qa9
  • View 1qa9
Molmil generated image of 1qa9
STRUCTURE OF A HETEROPHILIC ADHESION COMPLEX BETWEEN THE HUMAN CD2 AND CD58(LFA-3) COUNTER-RECEPTORS
Descriptor:HUMAN CD2 PROTEIN, HUMAN CD58 PROTEIN
Authors:Wang, J.-H., Smolyar, A., Tan, K., Liu, J.-H., Kim, M., Sun, Z.J., Wagner, G., Reinherz, E.L.
Deposit date:1999-04-13
Release date:1999-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors.
Cell(Cambridge,Mass.), 97, 1999
1BQH
  • Download 1bqh
  • View 1bqh
Molmil generated image of 1bqh
MURINE CD8AA ECTODOMAIN FRAGMENT IN COMPLEX WITH H-2KB/VSV8
Descriptor:PROTEIN (H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN), PROTEIN (BETA-2-MICROGLOBULIN ), PROTEIN (VSV8), ...
Authors:Wang, J.H., Reinherz, E.L., Kern, P.S., Chang, H.C.
Deposit date:1998-08-16
Release date:1998-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb.
Immunity, 9, 1998
1BWM
  • Download 1bwm
  • View 1bwm
Molmil generated image of 1bwm
A SINGLE-CHAIN T CELL RECEPTOR
Descriptor:PROTEIN (ALPHA-BETA T CELL RECEPTOR (TCR) (D10))
Authors:Hare, B.J., Wyss, D.F., Reinherz, E.L., Wagner, G.
Deposit date:1998-09-23
Release date:1999-07-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor.
Nat.Struct.Biol., 6, 1999
1CI5
  • Download 1ci5
  • View 1ci5
Molmil generated image of 1ci5
GLYCAN-FREE MUTANT ADHESION DOMAIN OF HUMAN CD58 (LFA-3)
Descriptor:PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58))
Authors:Sun, Z.Y.J., Dotsch, V., Kim, M., Li, J., Reinherz, E.L., Wagner, G.
Deposit date:1999-04-07
Release date:1999-06-22
Last modified:2018-03-14
Method:SOLUTION NMR
Cite:Functional glycan-free adhesion domain of human cell surface receptor CD58: design, production and NMR studies.
EMBO J., 18, 1999
1GYF
  • Download 1gyf
  • View 1gyf
Molmil generated image of 1gyf
GYF DOMAIN FROM HUMAN CD2BP2 PROTEIN
Descriptor:PROTEIN (CYTOPLASMIC DOMAIN BINDING PROTEIN (CD2BP2))
Authors:Freund, C., Doetsch, V., Nishizawa, K., Reinherz, E.L., Wagner, G.
Deposit date:1999-04-30
Release date:2000-01-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences.
Nat.Struct.Biol., 6, 1999
1JL4
  • Download 1jl4
  • View 1jl4
Molmil generated image of 1jl4
CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE
Descriptor:H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ...
Authors:Wang, J.-H., Meijers, R., Reinherz, E.L.
Deposit date:2001-07-15
Release date:2001-09-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.
Proc.Natl.Acad.Sci.USA, 98, 2001
1L2Z
  • Download 1l2z
  • View 1l2z
Molmil generated image of 1l2z
CD2BP2-GYF DOMAIN IN COMPLEX WITH PROLINE-RICH CD2 TAIL SEGMENT PEPTIDE
Descriptor:CD2 ANTIGEN (CYTOPLASMIC TAIL)-BINDING PROTEIN 2, T-CELL SURFACE ANTIGEN CD2
Authors:Freund, C., Kuhne, R., Yang, H., Park, S., Reinherz, E.L., Wagner, G.
Deposit date:2002-02-26
Release date:2002-11-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules
Embo J., 21, 2002
1NEZ
  • Download 1nez
  • View 1nez
Molmil generated image of 1nez
THE CRYSTAL STRUCTURE OF A TL/CD8AA COMPLEX AT 2.1A RESOLUTION:IMPLICATIONS FOR MEMORY T CELL GENERATION, CO-RECEPTOR PREFERENCE AND AFFINITY
Descriptor:H-2 class I histocompatibility antigen, TLA(C) alpha chain, Beta-2-microglobulin, ...
Authors:Liu, Y., Xiong, Y., Naidenko, O.V., Liu, J.H., Zhang, R., Joachimiak, A., Kronenberg, M., Cheroutre, H., Reinherz, E.L., Wang, J.H.
Deposit date:2002-12-12
Release date:2003-04-08
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Crystal Structure of a TL/CD8alphaalpha Complex at 2.1 A resolution: Implications for modulation of T cell activation and memory
Immunity, 18, 2003
1OSZ
  • Download 1osz
  • View 1osz
Molmil generated image of 1osz
MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN (L4V) MUTANT OF THE VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Descriptor:MHC CLASS I H-2KB HEAVY CHAIN, BETA-2 MICROGLOBULIN, VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Authors:Ghendler, Y., Teng, M.-K., Liu, J.-H., Witte, T., Liu, J., Kim, K.S., Kern, P., Chang, H.-C., Wang, J.-H., Reinherz, E.L.
Deposit date:1998-06-18
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands.
Proc.Natl.Acad.Sci.USA, 95, 1998
1WBX
  • Download 1wbx
  • View 1wbx
Molmil generated image of 1wbx
CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 DB AND KB MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
Descriptor:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, BETA-2MICROGLOBULIN, ...
Authors:Meijers, R., Lai, C., Yang, Y., Liu, J., Zhong, W., Wang, J., Reinherz, E.L.
Deposit date:2004-11-05
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1WBY
  • Download 1wby
  • View 1wby
Molmil generated image of 1wby
CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 DB AND KB MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
Descriptor:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, BETA-2MICROGLOBULIN, ...
Authors:Meijers, R., Lai, C., Yang, Y., Liu, J., Zhong, W., Wang, J., Reinherz, E.L.
Deposit date:2004-11-05
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1WBZ
  • Download 1wbz
  • View 1wbz
Molmil generated image of 1wbz
CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 DB AND KB MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
Descriptor:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN PRECURSOR, BETA-2MICROGLOBULIN, ...
Authors:Meijers, R., Lai, C., Yang, Y., Liu, J., Zhong, W., Wang, J., Reinherz, E.L.
Deposit date:2004-11-05
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1XMW
  • Download 1xmw
  • View 1xmw
Molmil generated image of 1xmw
CD3 EPSILON AND DELTA ECTODOMAIN FRAGMENT COMPLEX IN SINGLE-CHAIN CONSTRUCT
Descriptor:Chimeric CD3 mouse Epsilon and sheep Delta Ectodomain Fragment Complex
Authors:Sun, Z.-Y.J., Kim, S.T., Kim, I.C., Fahmy, A., Reinherz, E.L., Wagner, G.
Deposit date:2004-10-04
Release date:2004-11-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling.
Proc.Natl.Acad.Sci.Usa, 101, 2004
2ATP
  • Download 2atp
  • View 2atp
Molmil generated image of 2atp
CRYSTAL STRUCTURE OF A CD8AB HETERODIMER
Descriptor:T-cell surface glycoprotein CD8 alpha chain, artifact linker, T-cell surface glycoprotein CD8 beta chain, ...
Authors:Chang, H.C., Tan, K., Ouyang, J., Parisini, E., Liu, J.H., Le, Y., Wang, X., Reinherz, E.L., Wang, J.H.
Deposit date:2005-08-25
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Mutational Analyses of a CD8alphabeta Heterodimer and Comparison with the CD8alphaalpha Homodimer.
Immunity, 23, 2005
2JXB
  • Download 2jxb
  • View 2jxb
Molmil generated image of 2jxb
STRUCTURE OF CD3EPSILON-NCK2 FIRST SH3 DOMAIN COMPLEX
Descriptor:T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2
Authors:Takeuchi, K., Yang, H., Ng, E., Park, S., Sun, Z.J., Reinherz, E.L., Wagner, G.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.
J.Mol.Biol., 380, 2008
2ME1
  • Download 2me1
  • View 2me1
Molmil generated image of 2me1
HIV-1 GP41 CLADE B DOUBLE ALANINE MUTANT MEMBRANE PROXIMAL EXTERNAL REGION PEPTIDE IN DPC MICELLE
Descriptor:Gp41
Authors:Sun, Z.J., Wagner, G., Reinherz, E.L., Kim, M., Song, L., Choi, J., Cheng, Y., Chowdhury, B., Bellot, G., Shih, W.
Deposit date:2013-09-20
Release date:2013-10-09
Last modified:2014-03-05
Method:SOLUTION NMR
Cite:Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME2
  • Download 2me2
  • View 2me2
Molmil generated image of 2me2
HIV-1 GP41 CLADE C MEMBRANE PROXIMAL EXTERNAL REGION PEPTIDE IN DPC MICELLE
Descriptor:Envelope glycoprotein gp160
Authors:Sun, Z.J., Wagner, G., Reinherz, E.L., Kim, M., Song, L., Choi, J., Cheng, Y., Chowdhury, B., Bellot, G., Shih, W.
Deposit date:2013-09-20
Release date:2013-10-09
Last modified:2014-03-05
Method:SOLUTION NMR
Cite:Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME3
  • Download 2me3
  • View 2me3
Molmil generated image of 2me3
HIV-1 GP41 CLADE C MEMBRANE PROXIMAL EXTERNAL REGION PEPTIDE IN DPC MICELLE
Descriptor:Envelope glycoprotein gp160
Authors:Sun, Z.J., Wagner, G., Reinherz, E.L., Kim, M., Song, L., Choi, J., Cheng, Y., Chowdhury, B., Bellot, G., Shih, W.
Deposit date:2013-09-20
Release date:2013-10-09
Last modified:2014-03-05
Method:SOLUTION NMR
Cite:Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME4
  • Download 2me4
  • View 2me4
Molmil generated image of 2me4
HIV-1 GP41 CLADE C MEMBRANE PROXIMAL EXTERNAL REGION PEPTIDE IN DPC MICELLE
Descriptor:Envelope glycoprotein gp160
Authors:Sun, Z.J., Wagner, G., Reinherz, E.L., Kim, M., Song, L., Choi, J., Cheng, Y., Chowdhury, B., Bellot, G., Shih, W.
Deposit date:2013-09-20
Release date:2013-10-09
Last modified:2014-03-05
Method:SOLUTION NMR
Cite:Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2PV6
  • Download 2pv6
  • View 2pv6
Molmil generated image of 2pv6
HIV-1 GP41 MEMBRANE PROXIMAL ECTODOMAIN REGION PEPTIDE IN DPC MICELLE
Descriptor:Envelope glycoprotein
Authors:Sun, Z.-Y.J., Oh, K.J., Kim, M., Reinherz, E.L., Wagner, G.
Deposit date:2007-05-09
Release date:2008-03-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
Immunity, 28, 2008
6MF8
  • Download 6mf8
  • View 6mf8
Molmil generated image of 6mf8
TCR ALPHA TRANSMEMBRANE DOMAIN
Descriptor:T-cell receptor alpha chain C region
Authors:Brazin, K.N., Reinherz, E.L.
Deposit date:2018-09-10
Release date:2018-12-12
Method:SOLUTION NMR
Cite:The T Cell Antigen Receptor alpha Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Immunity, 49, 2018
1CDB
  • Download 1cdb
  • View 1cdb
Molmil generated image of 1cdb
STRUCTURE OF THE GLYCOSYLATED ADHESION DOMAIN OF HUMAN T LYMPHOCYTE GLYCOPROTEIN CD2
Descriptor:CD2
Authors:Wyss, D.F., Withka, J.M., Recny, M.A., Wagner, G.
Deposit date:1993-09-15
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2.
Structure, 1, 1993
<12>