Author results

1M1J
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CRYSTAL STRUCTURE OF NATIVE CHICKEN FIBRINOGEN WITH TWO DIFFERENT BOUND LIGANDS
Descriptor:Fibrinogen alpha subunit, Fibrinogen beta chain, Fibrinogen gamma chain, ...
Authors:Yang, Z., Kollman, J.M., Pandi, L., Doolittle, R.F.
Deposit date:2002-06-19
Release date:2002-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Native Chicken Fibrinogen at 2.7 A Resolution
Biochemistry, 40, 2001
1EI3
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CRYSTAL STRUCTURE OF NATIVE CHICKEN FIBRINOGEN
Descriptor:FIBRINOGEN
Authors:Yang, Z., Mochalkin, I., Veerapandian, L., Riley, M., Doolittle, R.F.
Deposit date:2000-02-23
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal structure of native chicken fibrinogen at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 97, 2000
1FZC
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CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH TWO DIFFERENT BOUND LIGANDS
Descriptor:FIBRIN, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Everse, S.J., Spraggon, G., Veerapandian, L., Riley, M., Doolittle, R.F.
Deposit date:1998-05-19
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of fragment double-D from human fibrin with two different bound ligands.
Biochemistry, 37, 1998
1N86
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CRYSTAL STRUCTURE OF HUMAN D-DIMER FROM CROSS-LINKED FIBRIN COMPLEXED WITH GPR AND GHRPLDK PEPTIDE LIGANDS.
Descriptor:Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain, ...
Authors:Yang, Z., Pandi, L., Doolittle, R.F.
Deposit date:2002-11-19
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
Biochemistry, 41, 2002
1SCW
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TOWARD BETTER ANTIBIOTICS: CRYSTAL STRUCTURE OF R61 DD-PEPTIDASE INHIBITED BY A NOVEL MONOCYCLIC PHOSPHATE INHIBITOR
Descriptor:D-alanyl-D-alanine carboxypeptidase, (2Z)-3-{[OXIDO(OXO)PHOSPHINO]OXY}-2-PHENYLACRYLATE, GLYCEROL
Authors:Silvaggi, N.R., Kaur, K., Adediran, S.A., Pratt, R.F., Kelly, J.A.
Deposit date:2004-02-12
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Toward Better Antibiotics: Crystallographic Studies of a Novel Class of DD-Peptidase/beta-Lactamase Inhibitors.
Biochemistry, 43, 2004
1SDE
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TOWARD BETTER ANTIBIOTICS: CRYSTAL STRUCTURE OF D-ALA-D-ALA PEPTIDASE INHIBITED BY A NOVEL BICYCLIC PHOSPHATE INHIBITOR
Descriptor:D-alanyl-D-alanine carboxypeptidase, 2-[(DIOXIDOPHOSPHINO)OXY]BENZOATE, GLYCEROL
Authors:Silvaggi, N.R., Kaur, K., Adediran, S.A., Pratt, R.F., Kelly, J.A.
Deposit date:2004-02-13
Release date:2004-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors
Biochemistry, 43, 2004
148D
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE THROMBIN BINDING DNA APTAMER D(GGTTGGTGTGGTTGG)
Descriptor:DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3')
Authors:Schultze, P., Macaya, R.F., Feigon, J.
Deposit date:1993-11-15
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG).
J.Mol.Biol., 235, 1994
1FKF
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ATOMIC STRUCTURE OF FKBP-FK506, AN IMMUNOPHILIN-IMMUNOSUPPRESSANT COMPLEX
Descriptor:FK506 BINDING PROTEIN, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
Authors:Vanduyne, G.D., Standaert, R.F., Karplus, P.A., Schreiber, S.L., Clardy, J.
Deposit date:1991-05-07
Release date:1991-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.
Science, 252, 1991
1JPS
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CRYSTAL STRUCTURE OF TISSUE FACTOR IN COMPLEX WITH HUMANIZED FAB D3H44
Descriptor:immunoglobulin Fab D3H44, light chain, heavy chain, ...
Authors:Faelber, K., Kirchhofer, D., Presta, L., Kelley, R.F., Muller, Y.A.
Deposit date:2001-08-03
Release date:2002-02-03
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
1JPT
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CRYSTAL STRUCTURE OF FAB D3H44
Descriptor:immunoglobulin Fab D3h44, light chain, immunoglobulin Fab D3H44, ...
Authors:Faelber, K., Kirchhofer, D., Presta, L., Kelley, R.F., Muller, Y.A.
Deposit date:2001-08-03
Release date:2002-02-03
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
1K6Q
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CRYSTAL STRUCTURE OF ANTIBODY FAB FRAGMENT D3
Descriptor:immunoglobulin Fab D3, light chain, heavy chain
Authors:Faelber, K., Kelley, R.F., Kirchhofer, D., Muller, Y.A.
Deposit date:2001-10-17
Release date:2002-04-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of murine Fab D3 at 2.4 A resolution in comparison with the humanised Fab D3h44 (1.85A) provides structural insight into the humanisation process of the D3 anti-tissue factor antibody
To be Published
1MPL
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CRYSTAL STRUCTURE OF PHOSPHONATE-INHIBITED D-ALA-D-ALA PEPTIDASE REVEALS AN ANALOG OF A TETRAHEDRAL TRANSITION STATE
Descriptor:D-alanyl-D-alanine carboxypeptidase, GLYCYL-L-A-AMINOPIMELYL-E-(D-2-AMINOETHYL)PHOSPHONATE, GLYCEROL
Authors:Silvaggi, N.R., Anderson, J.W., Brinsmade, S.R., Pratt, R.F., Kelly, J.A.
Deposit date:2002-09-12
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:The Crystal Structure of Phosphonate-Inhibited d-Ala-d-Ala Peptidase Reveals an Analogue of a Tetrahedral Transition State.
Biochemistry, 42, 2003
1N8E
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FRAGMENT DOUBLE-D FROM HUMAN FIBRIN
Descriptor:Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain
Authors:Yang, Z., Pandi, L., Doolittle, R.F.
Deposit date:2002-11-20
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface
Biochemistry, 41, 2002
1PW1
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NON-COVALENT COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH A HIGHLY SPECIFIC PENICILLIN
Descriptor:D-alanyl-D-alanine carboxypeptidase, (2S,5R,6R)-6-{[(6R)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE, GLYCEROL, ...
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-06-30
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PW8
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COVALENT ACYL ENZYME COMPLEX OF THE R61 DD-PEPTIDASE WITH A HIGHLY SPECIFIC CEPHALOSPORIN
Descriptor:D-alanyl-D-alanine carboxypeptidase, (6R,7R)-3-[(ACETYLOXY)METHYL]-7-{[(6S)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCTANE-2-CARBOXYLATE, GLYCEROL
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PWC
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PENICILLOYL ACYL ENZYME COMPLEX OF THE STREPTOMYCES R61 DD-PEPTIDASE WITH PENICILLIN G
Descriptor:D-alanyl-D-alanine carboxypeptidase, OPEN FORM - PENICILLIN G
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PWD
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COVALENT ACYL ENZYME COMPLEX OF THE STREPTOMYCES R61 DD-PEPTIDASE WITH CEPHALOSPORIN C
Descriptor:D-alanyl-D-alanine carboxypeptidase precursor, (2R)-5-(acetyloxymethyl)-2-[(1R)-1-[[(5R)-5-azanyl-6-oxidanyl-6-oxidanylidene-hexanoyl]amino]-2-oxidanylidene-ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PWG
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COVALENT PENICILLOYL ACYL ENZYME COMPLEX OF THE STREPTOMYCES R61 DD-PEPTIDASE WITH A HIGHLY SPECIFIC PENICILLIN
Descriptor:D-alanyl-D-alanine carboxypeptidase, (2R,4S)-2-[(1R)-1-{[(6S)-6-carboxy-6-(glycylamino)hexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.074 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1RAT
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EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K
Descriptor:RIBONUCLEASE A
Authors:Tiltonjunior, R.F., Dewan, J.C., Petsko, G.A.
Deposit date:1991-08-13
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.
Biochemistry, 31, 1992
2RAT
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EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K
Descriptor:RIBONUCLEASE A
Authors:Tiltonjunior, R.F., Dewan, J.C., Petsko, G.A.
Deposit date:1991-08-13
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.
Biochemistry, 31, 1992
3RAT
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EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K
Descriptor:RIBONUCLEASE A
Authors:Tiltonjunior, R.F., Dewan, J.C., Petsko, G.A.
Deposit date:1991-08-13
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.
Biochemistry, 31, 1992
442D
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5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(3-IODO-4-METHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, MAGNESIUM ION
Authors:Clark, G.R., Squire, C.J., Martin, R.F., White, J.
Deposit date:1999-01-14
Release date:2000-02-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
443D
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5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'/ BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(3-IODOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, MAGNESIUM ION
Authors:Squire, C.J., Baker, L.J., Clark, G.R., Martin, R.F., White, J.
Deposit date:1999-01-14
Release date:2000-02-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
444D
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5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(3-IODO-4-METHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
Authors:Clark, G.R., Squire, C.J., Martin, R.F., White, J.
Deposit date:1999-01-14
Release date:2000-02-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
445D
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5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(3-IODOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
Authors:Squire, C.J., Baker, L.J., Clark, G.R., Martin, R.F., White, J.
Deposit date:1999-01-14
Release date:2000-02-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000