6B6I

2.4A resolution structure of human Norovirus GII.4 protease

Summary for 6B6I

Entry DOI	10.2210/pdb6b6i/pdb
Descriptor	3C-like protease (2 entities in total)
Functional Keywords	3c-like protease, viral protease, gii.4, minerva, viral protein, protease
Biological source	Norovirus GII.4
Total number of polymer chains	8
Total formula weight	153937.38
Authors	Muzzarelli, K.M.,Kuiper, B.D.,Spellmon, N.S.,Hackett, J.,Brunzelle, J.S.,Kovari, I.A.,Amblard, F.,Yang, Z.,Schinazi, R.F.,Kovari, L.C. (deposition date: 2017-10-02, release date: 2018-10-03, Last modification date: 2023-10-04)
Primary citation	Muzzarelli, K.M.,Kuiper, B.,Spellmon, N.,Brunzelle, J.,Hackett, J.,Amblard, F.,Zhou, S.,Liu, P.,Kovari, I.A.,Yang, Z.,Schinazi, R.F.,Kovari, L.C. Structural and Antiviral Studies of the Human Norovirus GII.4 Protease. Biochemistry, 58:900-907, 2019 Cited by PubMed: 30605321 DOI: 10.1021/acs.biochem.8b01063 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.44 Å)

Structure validation