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5YWF
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CRYSTAL STRUCTURE OF 2H4 FAB
Descriptor:2H4 light chain, 2H4 heavy chain
Authors:Qiu, X., Lei, Y., Yang, P., Gao, Q., Wang, N., Cao, L., Wang, X., Xu, Z.K., Rao, Z.
Deposit date:2017-11-29
Release date:2018-03-21
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
5YWO
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STRUCTURE OF JEV-2F2 FAB COMPLEX
Descriptor:JEV E protein, JEV M protein, 2F2 light chain, ...
Authors:Qiu, X., Lei, Y.F., Yang, P., Gao, Q., Wang, N., Cao, L., Yuan, S., Wang, X., Xu, Z.K., Rao, Z.
Deposit date:2017-11-29
Release date:2018-03-21
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
1HND
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III-COA COMPLEX
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, COENZYME A
Authors:Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
1HNH
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III + DEGRADED FORM OF ACETYL-COA
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, COENZYME A
Authors:Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
1HNJ
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III + MALONYL-COA
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, PHOSPHATE ION, MALONYL-COENZYME A
Authors:Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
1HNK
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III, APO TETRAGONAL FORM
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III
Authors:Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
1THR
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STRUCTURES OF THROMBIN COMPLEXES WITH A DESIGNED AND A NATURAL EXOSITE INHIBITOR
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRULLIN
Authors:Qiu, X., Yin, M., Padmanabhan, K.P., Krstenansky, J.L., Tulinsky, A.
Deposit date:1993-06-16
Release date:1994-01-31
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.
J.Biol.Chem., 268, 1993
1THS
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STRUCTURES OF THROMBIN COMPLEXES WITH A DESIGNED AND A NATURAL EXOSITE INHIBITOR
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), SYNTHETIC INHIBITOR
Authors:Qiu, X., Yin, M., Padmanabhan, K.P., Krstenansky, J.L., Tulinsky, A.
Deposit date:1993-06-16
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.
J.Biol.Chem., 268, 1993
1VZV
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STRUCTURE OF VARICELLA-ZOSTER VIRUS PROTEASE
Descriptor:VARICELLA-ZOSTER VIRUS PROTEASE
Authors:Qiu, X., Jason, C.A., Culp, J.S., Richardson, S.B., Debouck, C., Smith, W.W., Abdel-Meguid, S.S.
Deposit date:1997-02-10
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of varicella-zoster virus protease.
Proc.Natl.Acad.Sci.USA, 94, 1997
5H4Z
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CRYSTAL STRUCTURE OF S202G MUTANT OF HUMAN SYT-5 C2A DOMAIN
Descriptor:Synaptotagmin-5, CALCIUM ION, CHLORIDE ION
Authors:Qiu, X., Ge, J., Yan, X., Gao, Y., Teng, M., Niu, L.
Deposit date:2016-11-02
Release date:2016-11-30
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain
Int. J. Biol. Macromol., 95, 2017
5ZBE
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CRYSTAL STRUCTURE OF AERE FROM MICROCYSTIS AERUGINOSA
Descriptor:Cupin domain protein, FE (II) ION, TRIETHYLENE GLYCOL
Authors:Qiu, X.
Deposit date:2018-02-11
Release date:2019-02-13
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional insights into the role of a cupin superfamily isomerase in the biosynthesis of Choi moiety of aeruginosin.
J. Struct. Biol., 205, 2019
5ZBF
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CRYSTAL STRUCTURE OF 4-HYDROXYPHENYLPYRUVIC ACID BOUND AERE FROM MICROCYSTIS AERUGINOSA
Descriptor:Cupin domain protein, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, FE (II) ION
Authors:Qiu, X., Zhu, W.
Deposit date:2018-02-11
Release date:2019-02-13
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional insights into the role of a cupin superfamily isomerase in the biosynthesis of Choi moiety of aeruginosin.
J. Struct. Biol., 205, 2019
1ABI
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STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRULOG 3
Authors:Qiu, X., Tulinsky, A.
Deposit date:1992-08-24
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.
Biochemistry, 31, 1992
1ABJ
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STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
Authors:Qiu, X., Tulinsky, A.
Deposit date:1992-08-24
Release date:1994-01-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.
Biochemistry, 31, 1992
1C14
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CRYSTAL STRUCTURE OF E COLI ENOYL REDUCTASE-NAD+-TRICLOSAN COMPLEX
Descriptor:ENOYL REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN
Authors:Qiu, X., Janson, C., Court, R., Smyth, M., Payne, D., Abdel-Meguid, S.
Deposit date:1999-07-20
Release date:2000-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for triclosan activity involves a flipping loop in the active site.
Protein Sci., 8, 1999
1HN9
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, PHOSPHATE ION
Authors:Qiu, X., Janson, C.A., Konstantinidis, A.K., Nwagwu, S., Silverman, C., Smith, W.W., Khandekar, S.K., Lonsdale, J., Abdel-Meguid, S.S.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis.
J.Biol.Chem., 274, 1999
1JII
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CRYSTAL STRUCTURE OF S. AUREUS TYRRS IN COMPLEX WITH SB-219383
Descriptor:tyrosyl-tRNA synthetase, [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]- (2,4,5,8-TETRAHYDROXY-7-OXA-2-AZA-BICYCLO[3.2.1]OCT-3-YL)- ACETIC ACID
Authors:Qiu, X., Janson, C.A., Smith, W.W., Jarvest, R.L.
Deposit date:2001-07-02
Release date:2001-10-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.
Protein Sci., 10, 2001
1JIJ
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CRYSTAL STRUCTURE OF S. AUREUS TYRRS IN COMPLEX WITH SB-239629
Descriptor:tyrosyl-tRNA synthetase, [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]-(1,3,4,5-TETRAHYDROXY-4-HYDROXYMETHYL-PIPERIDIN-2-YL)- ACETIC ACID
Authors:Qiu, X., Janson, C.A., Smith, W.W., Jarvest, R.L.
Deposit date:2001-07-02
Release date:2001-10-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.
Protein Sci., 10, 2001
1JIK
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CRYSTAL STRUCTURE OF S. AUREUS TYRRS IN COMPLEX WITH SB-243545
Descriptor:tyrosyl-tRNA synthetase, [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]-(1,3,4,5-TETRAHYDROXY-4-HYDROXYMETHYL-PIPERIDIN-2-YL)- ACETIC ACID BUTYL ESTER
Authors:Qiu, X., Janson, C.A., Smith, W.W., Jarvest, R.L.
Deposit date:2001-07-02
Release date:2001-10-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.
Protein Sci., 10, 2001
1JIL
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CRYSTAL STRUCTURE OF S. AUREUS TYRRS IN COMPLEX WITH SB284485
Descriptor:tyrosyl-tRNA synthetase, [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]- (3,4,5-TRIHYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YL)- ACETIC ACID
Authors:Qiu, X., Janson, C.A., Smith, W.W., Jarvest, R.L.
Deposit date:2001-07-02
Release date:2001-10-26
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.
Protein Sci., 10, 2001
1LAY
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CRYSTAL STRUCTURE OF CYTOMEGALOVIRUS PROTEASE
Descriptor:CYTOMEGALOVIRUS PROTEASE
Authors:Qiu, X., Culp, J.S., Dilella, A.G., Hellmig, B., Hoog, S.S., Jason, C.A., Smith, W.W., Abdel-Meguid, S.S.
Deposit date:1996-07-16
Release date:1997-09-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Unique fold and active site in cytomegalovirus protease.
Nature, 383, 1996
1QE0
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CRYSTAL STRUCTURE OF APO S. AUREUS HISTIDYL-TRNA SYNTHETASE
Descriptor:Histidine--tRNA ligase
Authors:Qiu, X., Janson, C.A., Blackburn, M.N., Chohan, I.K., Hibbs, M., Abdel-Meguid, S.S.
Deposit date:1999-07-12
Release date:2000-07-12
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cooperative structural dynamics and a novel fidelity mechanism in histidyl-tRNA synthetases.
Biochemistry, 38, 1999
1T8K
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CRYSTAL STRUCTURE OF APO ACYL CARRIER PROTEIN FROM E. COLI
Descriptor:Acyl carrier protein, ZINC ION, IMIDAZOLE
Authors:Qiu, X., Janson, C.A.
Deposit date:2004-05-13
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure of apo acyl carrier protein and a proposal to engineer protein crystallization through metal ions.
Acta Crystallogr.,Sect.D, 60, 2004
1ZOW
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CRYSTAL STRUCTURE OF S. AUREUS FABH, BETA-KETOACYL CARRIER PROTEIN SYNTHASE III
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase III
Authors:Qiu, X., Choudhry, A.E., Janson, C.A., Grooms, M., Daines, R.A., Lonsdale, J.T., Khandekar, S.S.
Deposit date:2005-05-15
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus.
Protein Sci., 14, 2005
2DTR
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STRUCTURE OF DIPHTHERIA TOXIN REPRESSOR
Descriptor:DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, COBALT (II) ION
Authors:Qiu, X., Pohl, E., Hol, W.G.
Deposit date:1996-07-26
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor.
Biochemistry, 35, 1996