1JIK
Crystal structure of S. aureus TyrRS in complex with SB-243545
Summary for 1JIK
Entry DOI | 10.2210/pdb1jik/pdb |
Related | 1JII 1JIJ 1JIL |
Descriptor | tyrosyl-tRNA synthetase, [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]-(1,3,4,5-TETRAHYDROXY-4-HYDROXYMETHYL-PIPERIDIN-2-YL)- ACETIC ACID BUTYL ESTER (3 entities in total) |
Functional Keywords | tyrosyl-trna synthetase, staphylococcus aureus, truncation, structure based inhibitor design, ligase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 48126.95 |
Authors | Qiu, X.,Janson, C.A.,Smith, W.W.,Jarvest, R.L. (deposition date: 2001-07-02, release date: 2001-10-26, Last modification date: 2024-02-07) |
Primary citation | Qiu, X.,Janson, C.A.,Smith, W.W.,Green, S.M.,McDevitt, P.,Johanson, K.,Carter, P.,Hibbs, M.,Lewis, C.,Chalker, A.,Fosberry, A.,Lalonde, J.,Berge, J.,Brown, P.,Houge-Frydrych, C.S.,Jarvest, R.L. Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors. Protein Sci., 10:2008-2016, 2001 Cited by PubMed: 11567092DOI: 10.1110/ps.18001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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