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6O0X
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BU of 6o0x by Molmil
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
Descriptor: 3' product of target strand DNA, 5' product of target strand DNA, CRISPR-associated endonuclease Cas9/Csn1, ...
Authors:Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
Deposit date:2019-02-17
Release date:2019-07-10
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
6O0Z
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BU of 6o0z by Molmil
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, non-target strand DNA, single guide RNA, ...
Authors:Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
Deposit date:2019-02-17
Release date:2019-07-10
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
6O0Y
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BU of 6o0y by Molmil
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
Descriptor: 3' product of target strand DNA, 5' product of target strand DNA, CRISPR-associated endonuclease Cas9/Csn1, ...
Authors:Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
Deposit date:2019-02-17
Release date:2019-07-10
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
8G9Z
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BU of 8g9z by Molmil
High-resolution crystal structure of the human selenomethionine-derived SepSecS-tRNASec complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, ...
Authors:Puppala, A, Simonovic, M, Castillo Suchkou, J.
Deposit date:2023-02-22
Release date:2023-04-05
Last modified:2023-05-17
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans.
Nucleic Acids Res., 51, 2023
4ZDO
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BU of 4zdo by Molmil
The crystal structure of T325S mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ...
Authors:French, R.L, Simonovic, M.
Deposit date:2015-04-17
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4ZDL
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BU of 4zdl by Molmil
The crystal structure of the T325S mutant of the human holo SepSecS
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, CITRATE ANION, O-phosphoseryl-tRNA(Sec) selenium transferase
Authors:French, R.L, Simonovic, M.
Deposit date:2015-04-17
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4ZDP
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BU of 4zdp by Molmil
The crystal structure of Y334C mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ...
Authors:French, R.L, Simonovic, M.
Deposit date:2015-04-17
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
7MDL
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BU of 7mdl by Molmil
High-resolution crystal structure of human SepSecS-tRNASec complex
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, CITRATE ANION, O-phosphoseryl-tRNA(Sec) selenium transferase, ...
Authors:Puppala, A, French, R.L, Simonovic, M.
Deposit date:2021-04-05
Release date:2022-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans.
Nucleic Acids Res., 2023
7L1T
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BU of 7l1t by Molmil
Crystal structure of human holo SepSecS
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION
Authors:Puppala, A, Castillo Suchkou, J, Simonovic, M.
Deposit date:2020-12-15
Release date:2022-02-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans.
Nucleic Acids Res., 2023

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PDB entries from 2024-09-18

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