Author results

1MNB
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BIV TAT PEPTIDE (RESIDUES 68-81), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:BIV TAR RNA, BIV TAT PEPTIDE
Authors:Puglisi, J.D., Chen, L., Blanchard, S., Frankel, A.D.
Deposit date:1996-07-25
Release date:1997-01-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a bovine immunodeficiency virus Tat-TAR peptide-RNA complex.
Science, 270, 1995
2M4Q
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NMR STRUCTURE OF E. COLI RIBOSOMELA DECODING SITE WITH APRAMYCIN
Descriptor:RNA (27-MER), APRAMYCIN
Authors:Puglisi, J.D., Tsai, A., Marshall, R., Viani, E.
Deposit date:2013-02-10
Release date:2013-03-20
Method:SOLUTION NMR
Cite:The impact of aminoglycosides on the dynamics of translation elongation.
Cell Rep, 3, 2013
1I3Y
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SOLUTION STRUCTURE OF THE A LOOP OF 23S RIBOSOMAL RNA.
Descriptor:5'-R(*GP*GP*CP*UP*GP*GP*CP*(OMU)P*GP*UP*UP*CP*GP*CP*CP*AP*GP*CP*C)-3'
Authors:Puglisi, J.D., Blanchard, S.C.
Deposit date:2001-02-17
Release date:2001-04-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the A loop of 23S ribosomal RNA.
Proc.Natl.Acad.Sci.USA, 98, 2001
1BVJ
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HIV-1 RNA A-RICH HAIRPIN LOOP
Descriptor:RNA (5'-R(P*GP*GP*CP*GP*AP*CP*GP*GP*UP*GP*UP*AP*AP*AP*AP*AP*UP*CP*UP*CP*GP*CP* C)-3')
Authors:Puglisi, E.V., Puglisi, J.D.
Deposit date:1998-08-31
Release date:1998-12-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:HIV-1 A-rich RNA loop mimics the tRNA anticodon structure.
Nat.Struct.Biol., 5, 1998
1VOP
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CONSERVED RNA COMPONENT OF THE PEPTIDYL TRANSFERASE CENTER, NMR, 33 STRUCTURES
Descriptor:23S RIBOSOMAL RNA
Authors:Puglisi, E.V., Puglisi, J.D.
Deposit date:1997-08-30
Release date:1997-12-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a conserved RNA component of the peptidyl transferase centre.
Nat.Struct.Biol., 4, 1997
5BR8
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AMBIENT-TEMPERATURE CRYSTAL STRUCTURE OF 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH PAROMOMYCIN
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Sierra, R.G., Gati, C., Laksmono, H., Dao, E.H., Gul, S., Fuller, F., Kern, J., Chatterjee, R., Ibrahim, M., Brewster, A., Young, I.D., Michels-Clark, T., Aquila, A., Mengning, L., Hunter, M.S., Koglin, J.E., Boutet, S., Junco, E.A., Hayes, B., Bogan, M.J., Hampton, C.Y., Puglisi, E.V., Sauter, N.K., Stan, C.A., Zouni, A., Yano, J., Yachandra, V.K., Soltis, S.M., Puglisi, J.D., DeMirci, H.
Deposit date:2015-05-29
Release date:2015-11-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin
To Be Published
6B19
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ARCHITECTURE OF HIV-1 REVERSE TRANSCRIPTASE INITIATION COMPLEX CORE
Descriptor:reverse transcriptase p66 subunit, reverse transcriptase p51 subunit, RNA genome fragment, ...
Authors:Larsen, K.P., Mathiharan, Y.K., Chen, D.H., Puglisi, J.D., Skiniotis, G., Puglisi, E.V.
Deposit date:2017-09-18
Release date:2018-04-25
Last modified:2018-05-09
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Architecture of an HIV-1 reverse transcriptase initiation complex.
Nature, 557, 2018
1A3M
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PAROMOMYCIN BINDING INDUCES A LOCAL CONFORMATIONAL CHANGE IN THE A SITE OF 16S RRNA, NMR, 20 STRUCTURES
Descriptor:16S RRNA (5'-R(*GP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*UP*UP*C)-3'), 16S RRNA (5'-R(*GP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*C)-3')
Authors:Fourmy, D., Yoshizawa, S., Puglisi, J.D.
Deposit date:1998-01-22
Release date:1998-04-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA.
J.Mol.Biol., 277, 1998
1BYJ
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GENTAMICIN C1A A-SITE COMPLEX
Descriptor:RNA (16S RNA), 3,4-DIDEOXY-2,6-AMINO-ALPHA-D GALACTOPYRANOSE, 3,5-DIAMINO-CYCLOHEXANOL, ...
Authors:Yoshizawa, S., Fourmy, D., Puglisi, J.D.
Deposit date:1998-10-16
Release date:1999-10-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural origins of gentamicin antibiotic action.
EMBO J., 17, 1998
1F84
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SOLUTION STRUCTURE OF HCV IRES RNA DOMAIN IIID
Descriptor:HCV-1B IRES RNA DOMAIN IIID
Authors:Lukavsky, P.J., Otto, G.A., Lancaster, A.M., Sarnow, P., Puglisi, J.D.
Deposit date:2000-06-28
Release date:2000-11-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function.
Nat.Struct.Biol., 7, 2000
1F85
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SOLUTION STRUCTURE OF HCV IRES RNA DOMAIN IIIE
Descriptor:HCV-1B IRES RNA DOMAIN IIIE
Authors:Lukavsky, P.J., Otto, G.A., Lancaster, A.M., Sarnow, P., Puglisi, J.D.
Deposit date:2000-06-28
Release date:2000-11-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function.
Nat.Struct.Biol., 7, 2000
1FYO
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EUKARYOTIC DECODING REGION A-SITE RNA
Descriptor:FRAGMENT OF 18S RIBOSOMAL RNA
Authors:Lynch, S.R., Puglisi, J.D.
Deposit date:2000-10-02
Release date:2001-03-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a eukaryotic decoding region A-site RNA.
J.Mol.Biol., 306, 2001
1FYP
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EUKARYOTIC DECODING REGION A-SITE RNA-PAROMOMYCIN COMPLEX
Descriptor:FRAGMENT OF 18S RIBOSOMAL RNA, PAROMOMYCIN
Authors:Lynch, S.R., Puglisi, J.D.
Deposit date:2000-10-02
Release date:2001-03-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural origins of aminoglycoside specificity for prokaryotic ribosomes.
J.Mol.Biol., 306, 2001
1I3X
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SOLUTION STRUCTURE OF THE A LOOP OF 23S RIBOSOMAL RNA
Descriptor:5'-R(*GP*GP*CP*UP*GP*GP*CP*UP*GP*UP*UP*CP*GP*CP*CP*AP*GP*CP*C)-3'
Authors:Blanchard, S.C., Puglisi, J.D.
Deposit date:2001-02-17
Release date:2001-04-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the A loop of 23S ribosomal RNA.
Proc.Natl.Acad.Sci.USA, 98, 2001
1P5M
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SOLUTION STRUCTURE OF HCV IRES DOMAIN IIA
Descriptor:55-MER
Authors:Lukavsky, P.J., Kim, I., Otto, G.A., Puglisi, J.D.
Deposit date:2003-04-27
Release date:2003-11-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of HCV IRES domain II determined by NMR.
Nat.Struct.Biol., 10, 2003
1P5N
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SOLUTION STRUCTURE OF HCV IRES DOMAIN IIB
Descriptor:34-MER
Authors:Lukavsky, P.J., Kim, I., Otto, G.A., Puglisi, J.D.
Deposit date:2003-04-27
Release date:2003-11-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of HCV IRES domain II determined by NMR.
Nat.Struct.Biol., 10, 2003
1P5O
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SOLUTION STRUCTURE OF HCV IRES DOMAIN II
Descriptor:77-MER
Authors:Lukavsky, P.J., Kim, I., Otto, G.A., Puglisi, J.D.
Deposit date:2003-04-27
Release date:2003-11-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of HCV IRES domain II determined by NMR.
Nat.Struct.Biol., 10, 2003
1P5P
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SOLUTION STRUCTURE OF HCV IRES DOMAIN II (MINIMIZED AVERAGE STRUCTURE)
Descriptor:77-MER
Authors:Lukavsky, P.J., Kim, I., Otto, G.A., Puglisi, J.D.
Deposit date:2003-04-27
Release date:2003-11-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of HCV IRES domain II determined by NMR.
Nat.Struct.Biol., 10, 2003
1PBR
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STRUCTURE OF 16S RIBOSOMAL RNA, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:16S RIBOSOMAL RNA, 2-amino-2-deoxy-alpha-D-glucopyranose, 2-DEOXYSTREPTAMINE, ...
Authors:Fourmy, D., Recht, M.I., Blanchard, S., Puglisi, J.D.
Deposit date:1996-09-12
Release date:1997-09-17
Last modified:2013-01-16
Method:SOLUTION NMR
Cite:Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic.
Science, 274, 1996
2JU1
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SOLUTION STRUCTURE OF ACYL CARRIER PROTEIN DOMAIN FROM MODULE 2 OF 6-DEOXYERYTHRONOLIDE B SYNTHASE (DEBS)
Descriptor:Erythronolide synthase
Authors:Alekseyev, V.Y., Liu, C.W., Puglisi, J.D., Khosla, C.
Deposit date:2007-08-12
Release date:2007-10-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and proposed domain domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase.
Protein Sci., 16, 2007
2JU2
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MINIMIZED MEAN SOLUTION STRUCTURE OF THE ACYL CARRIER PROTEIN DOMAIN FROM MODULE 2 OF 6-DEOXYERYTHRONOLIDE B SYNTHASE (DEBS)
Descriptor:Erythronolide synthase
Authors:Alekseyev, V.Y., Liu, C.W., Puglisi, J.D., Khosla, C.
Deposit date:2007-08-12
Release date:2007-10-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and proposed domain domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase.
Protein Sci., 16, 2007
3J4J
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MODEL OF FULL-LENGTH T. THERMOPHILUS TRANSLATION INITIATION FACTOR 2 REFINED AGAINST ITS CRYO-EM DENSITY FROM A 30S INITIATION COMPLEX MAP
Descriptor:Translation initiation factor IF-2
Authors:Simonetti, A., Marzi, S., Billas, I.M.L., Tsai, A., Fabbretti, A., Myasnikov, A., Roblin, P., Vaiana, A.C., Hazemann, I., Eiler, D., Steitz, T.A., Puglisi, J.D., Gualerzi, C.O., Klaholz, B.P.
Deposit date:2013-08-26
Release date:2013-09-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor.
Proc.Natl.Acad.Sci.USA, 110, 2013
3KJ6
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CRYSTAL STRUCTURE OF A METHYLATED BETA2 ADRENERGIC RECEPTOR-FAB COMPLEX
Descriptor:Beta-2 adrenergic receptor, Fab light chain, Fab heavy chain, ...
Authors:Bokoch, M.P., Zou, Y., Rasmussen, S.G.F., Liu, C.W., Nygaard, R., Rosenbaum, D.M., Fung, J.J., Choi, H.-J., Thian, F.S., Kobilka, T.S., Puglisi, J.D., Weis, W.I., Pardo, L., Prosser, S., Mueller, L., Kobilka, B.K.
Deposit date:2009-11-02
Release date:2010-02-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463, 2010
4X62
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CRYSTAL STRUCTURE OF 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Demirci, H., Chen, J., Choi, J., Soltis, M., Puglisi, J.D.
Deposit date:2014-12-06
Release date:2015-11-18
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.4492 Å)
Cite:N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics.
Nat.Struct.Mol.Biol., 23, 2016
4X64
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CRYSTAL STRUCTURE OF 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Demirci, H., Chen, J., Choi, J., Soltis, M., Puglisi, J.D.
Deposit date:2014-12-06
Release date:2015-11-18
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics.
Nat.Struct.Mol.Biol., 23, 2016
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