Author results

1LUD
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SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES
Descriptor:DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM
Authors:Polshakov, V.I., Smirnov, E.G., Birdsall, B., Kelly, G., Feeney, J.
Deposit date:2002-05-22
Release date:2002-12-18
Last modified:2016-12-28
Method:SOLUTION NMR
Cite:NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH
J.Biomol.Nmr, 24, 2002
1BZF
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NMR SOLUTION STRUCTURE AND DYNAMICS OF THE COMPLEX OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE WITH THE NEW LIPOPHILIC ANTIFOLATE DRUG TRIMETREXATE, 22 STRUCTURES
Descriptor:DIHYDROFOLATE REDUCTASE, TRIMETREXATE
Authors:Polshakov, V.I., Birdsall, B., Frenkiel, T.A., Gargaro, A.R., Feeney, J.
Deposit date:1998-10-28
Release date:1999-05-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.
Protein Sci., 8, 1999
2LLX
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN POLYPEPTIDE CHAIN RELEASE FACTOR ERF1
Descriptor:Eukaryotic peptide chain release factor subunit 1
Authors:Polshakov, V.I., Eliseev, B.D., Birdsall, B., Frolova, L.Y.
Deposit date:2011-11-18
Release date:2012-05-30
Method:SOLUTION NMR
Cite:Structure and dynamics in solution of the stop codon decoding N-terminal domain of the human polypeptide chain release factor eRF1.
Protein Sci., 21, 2012
5LFY
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ZINC BOUND DIMER OF THE FRAGMENT OF HUMAN AMYLOID-BETA PEPTIDE WITH ALZHEIMER'S DISEASE PATHOGENIC TAIWANESE MUTATION D7H
Descriptor:Amyloid beta A4 protein, ZINC ION
Authors:Polshakov, V.I., Mantsyzov, A.B., Kozin, S.A.
Deposit date:2016-07-05
Release date:2017-08-23
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-beta Fragment with Taiwanese Mutation D7H.
Angew. Chem. Int. Ed. Engl., 56, 2017
1PS2
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HIGH RESOLUTION NMR SOLUTION STRUCTURE OF HUMAN PS2, 19 STRUCTURES
Descriptor:PS2
Authors:Williams, M.A., Polshakov, V.I., Gargaro, A.R., Feeney, J.
Deposit date:1997-01-07
Release date:1997-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.
J.Mol.Biol., 267, 1997
5LGF
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF OGATAEA POLYMORPHA TELOMERASE REVERSE TRANSCRIPTASE
Descriptor:Telomerase reverse transcriptase
Authors:Polshakov, V.I., Mantsyzov, A.B., Efimov, S.V.
Deposit date:2016-07-07
Release date:2017-07-19
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Nucleic Acids Res., 46, 2018
1YHO
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SOLUTION STRUCTURE OF HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 25 STRUCTURES
Descriptor:Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM
Authors:Polshakov, V.I., Birdsall, B.
Deposit date:2005-01-10
Release date:2005-11-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.
J.Biomol.Nmr, 33, 2005
2HM9
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SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM, 33 STRUCTURES
Descriptor:Dihydrofolate reductase, 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM
Authors:Polshakov, V.I., Birdsall, B.
Deposit date:2006-07-11
Release date:2007-06-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of apo L.casei dihydrofolate reductase and its complexes with trimethoprim and NADPH. Contributions to positive cooperative binding from ligand-induced refolding, conformational changes and interligand hydrophobic interactions
Biochemistry, 2011
2HQP
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SOLUTION STRUCTURE OF L.CASEI DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH, 32 STRUCTURES
Descriptor:Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Polshakov, V.I., Birdsall, B.
Deposit date:2006-07-19
Release date:2007-06-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insights into cooperative effects of ligand binding to L. casei dihydrofolate redutase
TO BE PUBLISHED
2HST
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SOLUTION STRUCTURE OF THE MIDDLE DOMAIN OF HUMAN EUKARYOTIC TRANSLATION TERMINATION FACTOR ERF1
Descriptor:Eukaryotic peptide chain release factor subunit 1
Authors:Polshakov, V.I., Birdsall, B., Kisselev, L.L.
Deposit date:2006-07-23
Release date:2007-06-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Eukaryotic class 1 translation termination factor eRF1 - the NMR structure and dynamics of the middle domain involved in triggering ribosome-dependent peptidyl-tRNA hydrolysis
Febs J., 274, 2007
2L28
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SOLUTION STRUCTURE OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE APO-FORM, 25 CONFORMERS
Descriptor:Dihydrofolate reductase
Authors:Polshakov, V.I., Birdsall, B., Feeney, J.
Deposit date:2010-08-13
Release date:2011-04-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions.
Biochemistry, 50, 2011
1DIS
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DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
Descriptor:DIHYDROFOLATE REDUCTASE, BRODIMOPRIM-4,6-DICARBOXYLATE
Authors:Morgan, W.D., Birdsall, B., Polshakov, V.I., Sali, D., Kompis, I., Feeney, J.
Deposit date:1995-08-01
Release date:1995-11-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
1DIU
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DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
Descriptor:DIHYDROFOLATE REDUCTASE, BRODIMOPRIM-4,6-DICARBOXYLATE
Authors:Morgan, W.D., Birdsall, B., Polshakov, V.I., Sali, D., Kompis, I., Feeney, J.
Deposit date:1995-08-01
Release date:1995-11-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
2KTV
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HUMAN ERF1 C-DOMAIN, "OPEN" CONFORMER
Descriptor:Eukaryotic peptide chain release factor subunit 1
Authors:Mantsyzov, A.B., Polshakov, V.I., Birdsall, B.
Deposit date:2010-02-09
Release date:2010-06-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor.
Febs J., 277, 2010
6Q44
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EST3 TELOMERASE SUBUNIT IN THE YEAST HANSENULA POLYMORPHA
Descriptor:Uncharacterized protein
Authors:Mantsyzov, A.B., Mariasina, S.S., Petrova, O.A., Efimov, S.V., Dontsova, O.A., Polshakov, V.I.
Deposit date:2018-12-05
Release date:2019-12-25
Method:SOLUTION NMR
Cite:NMR structure of Est3 from the Hansenula polymorpha telomerase
To Be Published
1AO8
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES
Descriptor:DIHYDROFOLATE REDUCTASE, METHOTREXATE
Authors:Gargaro, A.R., Soteriou, A., Frenkiel, T.A., Bauer, C.J., Birdsall, B., Polshakov, V.I., Barsukov, I.L., Roberts, G.C.K., Feeney, J.
Deposit date:1997-07-22
Release date:1998-02-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
J.Mol.Biol., 277, 1998
2KTU
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HUMAN ERF1 C-DOMAIN, "CLOSED" CONFORMER
Descriptor:Eukaryotic peptide chain release factor subunit 1
Authors:Mantsyzov, A.B., Polshakov, V.I., Birdsall, B.
Deposit date:2010-02-09
Release date:2010-06-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR assignments of the C-terminal domain of human polypeptide release factor eRF1.
Biomol.Nmr Assign., 1, 2007
2MGT
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ZINC INDUCED DIMER OF THE METAL BINDING DOMAIN 1-16 OF HUMAN AMYLOID BETA-PEPTIDE WITH ALZHEIMER'S DISEASE PATHOGENIC ENGLISH MUTATION H6R
Descriptor:Amyloid beta A4 protein, ZINC ION
Authors:Polshakov, V., Istrate, A., Kozin, S.
Deposit date:2013-11-06
Release date:2014-11-12
Last modified:2020-01-01
Method:SOLUTION NMR
Cite:Interplay of histidine residues of the Alzheimer's disease A beta peptide governs its Zn-induced oligomerization.
Sci Rep, 6, 2016
2LI9
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METAL BINDING DOMAIN OF RAT BETA-AMYLOID
Descriptor:Amyloid beta A4 protein, ZINC ION
Authors:Polshakov, V., Istrate, A., Kozin, S., Makarov, A.
Deposit date:2011-08-25
Release date:2012-01-18
Last modified:2012-03-21
Method:SOLUTION NMR
Cite:NMR solution structure of rat Abeta(1-16): toward understanding the mechanism of rats' resistance to Alzheimer's disease.
Biophys.J., 102, 2012
2LF1
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SOLUTION STRUCTURE OF L. CASEI DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH, 30 STRUCTURES
Descriptor:Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Polshakov, V., Feeney, J., Birdsall, B., Kovalevskaya, N.
Deposit date:2011-06-28
Release date:2011-12-21
Method:SOLUTION NMR
Cite:NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions
Biochemistry, 50, 2011
1HI7
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NMR SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED HOMODIMER OF HUMAN TFF1, 10 STRUCTURES
Descriptor:PS2 PROTEIN
Authors:Williams, M.A., Feeney, J.
Deposit date:2001-01-03
Release date:2001-01-03
Last modified:2019-04-10
Method:SOLUTION NMR
Cite:The Solution Structure of the Disulphide-Linked Dimeric of the Human Trefoil Protein Tff1
FEBS Lett., 493, 2001
5NPT
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STRUCTURE OF THE N-TERMINAL DOMAIN OF THE YEAST TELOMERASE REVERSE TRANSCRIPTASE
Descriptor:Telomerase reverse transcriptase
Authors:Rodina, E.V., Lebedev, A.A., Hakanpaa, J., Hackenberg, C., Petrova, O.A., Zvereva, M.I., Dontsova, O.A., Lamzin, V.S.
Deposit date:2017-04-18
Release date:2017-12-20
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Nucleic Acids Res., 46, 2018