1AO8
DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES
Summary for 1AO8
Entry DOI | 10.2210/pdb1ao8/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, METHOTREXATE (2 entities in total) |
Functional Keywords | oxidoreductase, inhibitor-enzyme complex |
Biological source | Lactobacillus casei |
Total number of polymer chains | 1 |
Total formula weight | 18786.03 |
Authors | Gargaro, A.R.,Soteriou, A.,Frenkiel, T.A.,Bauer, C.J.,Birdsall, B.,Polshakov, V.I.,Barsukov, I.L.,Roberts, G.C.K.,Feeney, J. (deposition date: 1997-07-22, release date: 1998-02-25, Last modification date: 2024-05-22) |
Primary citation | Gargaro, A.R.,Soteriou, A.,Frenkiel, T.A.,Bauer, C.J.,Birdsall, B.,Polshakov, V.I.,Barsukov, I.L.,Roberts, G.C.,Feeney, J. The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate. J.Mol.Biol., 277:119-134, 1998 Cited by PubMed: 9514736DOI: 10.1006/jmbi.1997.1560 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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