2MGT
Zinc induced dimer of the metal binding domain 1-16 of human amyloid beta-peptide with Alzheimer's disease pathogenic English mutation H6R
Summary for 2MGT
Entry DOI | 10.2210/pdb2mgt/pdb |
NMR Information | BMRB: 19602 |
Descriptor | Amyloid beta A4 protein, ZINC ION (2 entities in total) |
Functional Keywords | alzheimer's disease, human amyloid -peptide, zinc binding, protein fibril, metal binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 4071.69 |
Authors | Polshakov, V.,Istrate, A.,Kozin, S. (deposition date: 2013-11-06, release date: 2014-11-12, Last modification date: 2020-01-01) |
Primary citation | Istrate, A.N.,Kozin, S.A.,Zhokhov, S.S.,Mantsyzov, A.B.,Kechko, O.I.,Pastore, A.,Makarov, A.A.,Polshakov, V.I. Interplay of histidine residues of the Alzheimer's disease A beta peptide governs its Zn-induced oligomerization. Sci Rep, 6:21734-21734, 2016 Cited by PubMed: 26898943DOI: 10.1038/srep21734 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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