1DIS
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
Summary for 1DIS
| Entry DOI | 10.2210/pdb1dis/pdb |
| Descriptor | DIHYDROFOLATE REDUCTASE, BRODIMOPRIM-4,6-DICARBOXYLATE (2 entities in total) |
| Functional Keywords | inhibitor-enzyme complex, oxido-reductase, oxidoreductase |
| Biological source | Lactobacillus casei |
| Total number of polymer chains | 1 |
| Total formula weight | 18827.93 |
| Authors | Morgan, W.D.,Birdsall, B.,Polshakov, V.I.,Sali, D.,Kompis, I.,Feeney, J. (deposition date: 1995-08-01, release date: 1995-11-14, Last modification date: 2022-02-16) |
| Primary citation | Morgan, W.D.,Birdsall, B.,Polshakov, V.I.,Sali, D.,Kompis, I.,Feeney, J. Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase. Biochemistry, 34:11690-11702, 1995 Cited by PubMed: 7547901DOI: 10.1021/bi00037a006 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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