2L28
Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers
Summary for 2L28
Entry DOI | 10.2210/pdb2l28/pdb |
Related | 1LUD 1YHO 2HM9 2HQP |
NMR Information | BMRB: 17125 |
Descriptor | Dihydrofolate reductase (1 entity in total) |
Functional Keywords | oxidoreductase, dhfr, antifolates, co-operative binding |
Biological source | Lactobacillus casei |
Total number of polymer chains | 1 |
Total formula weight | 18331.59 |
Authors | Polshakov, V.I.,Birdsall, B.,Feeney, J. (deposition date: 2010-08-13, release date: 2011-04-06, Last modification date: 2024-05-01) |
Primary citation | Feeney, J.,Birdsall, B.,Kovalevskaya, N.V.,Smurnyy, Y.D.,Navarro Peran, E.M.,Polshakov, V.I. NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions. Biochemistry, 50:3609-3620, 2011 Cited by PubMed: 21410224DOI: 10.1021/bi200067t PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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