Author results

1N3J
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STRUCTURE AND SUBSTRATE OF A HISTONE H3 LYSINE METHYLTRANSFERASE FROM PARAMECIUM BURSARIA CHLORELLA VIRUS 1
Descriptor:Histone H3 Lysine Methyltransferase
Authors:Manzur, K.L., Farooq, A., Zeng, L., Plotnikova, O., Sachchidanand, Koch, A.W., Zhou, M.-M.
Deposit date:2002-10-28
Release date:2003-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3.
Nat.Struct.Biol., 10, 2003
1XR0
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STRUCTURAL BASIS OF SNT PTB DOMAIN INTERACTIONS WITH DISTINCT NEUROTROPHIC RECEPTORS
Descriptor:Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1
Authors:Dhalluin, C., Yan, K.S., Plotnikova, O., Lee, K.W., Zeng, L., Kuti, M., Mujtaba, S., Goldfarb, M.P., Zhou, M.-M.
Deposit date:2004-10-13
Release date:2004-11-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Mol.Cell, 6, 2000
1Y6Z
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MIDDLE DOMAIN OF PLASMODIUM FALCIPARUM PUTATIVE HEAT SHOCK PROTEIN PF14_0417
Descriptor:heat shock protein, putative
Authors:Lunin, V.V., Botchkareva, E., Loppnau, P., Amani, M., Bray, J., Vedadi, M., Edwards, A., Arrowsmith, C., Sundstrom, M., Bochkarev, A., Hui, R., Plotnikova, O., Structural Genomics Consortium (SGC)
Deposit date:2004-12-07
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2RO1
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NMR SOLUTION STRUCTURES OF HUMAN KAP1 PHD FINGER-BROMODOMAIN
Descriptor:Transcription intermediary factor 1-beta, ZINC ION
Authors:Zeng, L., Yap, K.L., Ivanov, A.V., Wang, X., Mujtaba, S., Plotnikova, O., Rauscher, F.J.
Deposit date:2008-03-04
Release date:2008-05-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing
Nat.Struct.Mol.Biol., 15, 2008
3IED
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PLASMODIUM FALCIPARUM HSP90 (PF14_0417) IN COMPLEX WITH AMPPN
Descriptor:Heat shock protein, AMP PHOSPHORAMIDATE
Authors:Pizarro, J.C., Wernimont, A.K., Lew, J., Hutchinson, A., Artz, J.D., Amaya, M.F., Plotnikova, O., Vedadi, M., Kozieradzki, I., Weigelt, J., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Botchkarev, A., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2009-07-22
Release date:2009-08-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF14_0417) in complex with AMPPN
TO BE PUBLISHED
4JS8
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CRYSTAL STRUCTURE OF TTK KINASE DOMAIN WITH AN INHIBITOR: 401348
Descriptor:Dual specificity protein kinase TTK, 4-(cyclohexylmethoxy)-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-2H-indazole, SULFATE ION, ...
Authors:Qiu, W., Plotnikov, A.N., Plotnikova, O., Feher, M., Awrey, D.E., Chirgadze, N.Y.
Deposit date:2013-03-22
Release date:2014-03-26
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal structure of TTK kinase domain with an inhibitor: 401348
To be Published
4JXF
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CRYSTAL STRUCTURE OF PLK4 KINASE WITH AN INHIBITOR: 400631 ((1R,2S)-2-{3-[(E)-2-{4-[(DIMETHYLAMINO)METHYL]PHENYL}ETHENYL]-2H-INDAZOL-6-YL}-5'-METHOXYSPIRO[CYCLOPROPANE-1,3'-INDOL]-2'(1'H)-ONE)
Descriptor:Serine/threonine-protein kinase PLK4, (1R,2S)-2-{3-[(E)-2-{4-[(dimethylamino)methyl]phenyl}ethenyl]-2H-indazol-6-yl}-5'-methoxyspiro[cyclopropane-1,3'-indol]-2'(1'H)-one, 1,2-ETHANEDIOL
Authors:Qiu, W., Plotnikova, O., Feher, M., Awrey, D.E., Chirgadze, N.Y.
Deposit date:2013-03-28
Release date:2014-04-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of PLK4 Kinase with an inhibitor: 400631
To be Published
4O6L
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CRYSTAL STRUCTURE OF TTK KINASE DOMAIN WITH AN INHIBITOR: 401498 (N-[(1R)-1-(2-CHLOROPHENYL)PROPYL]-3-{4-[(1-METHYLPIPERIDIN-4-YL)OXY]PHENYL}-1H-INDAZOLE-5-CARBOXAMIDE)
Descriptor:Dual specificity protein kinase TTK, N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide, GLYCEROL
Authors:Qiu, W., Plotnikova, O., Feher, M., Awrey, D.E., Chirgadze, N.Y.
Deposit date:2013-12-22
Release date:2014-12-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal Structure of TTK kinase domain with an inhibitor: 401498
TO BE PUBLISHED
4ZEG
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CRYSTAL STRUCTURE OF TTK KINASE DOMAIN IN COMPLEX WITH A PYRAZOLOPYRIMIDINE INHIBITOR
Descriptor:Dual specificity protein kinase TTK, GLYCEROL, DI(HYDROXYETHYL)ETHER, ...
Authors:Qiu, W., Plotnikova, O., Feher, M., Awrey, D.E., Battaile, K., Chirgadze, N.Y.
Deposit date:2015-04-20
Release date:2016-04-27
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal structure of TTK kinase domain in complex with a pyrazolopyrimidine inhibitor.
To Be Published
2F6I
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CRYSTAL STRUCTURE OF THE CLPP PROTEASE CATALYTIC DOMAIN FROM PLASMODIUM FALCIPARUM
Descriptor:ATP-dependent CLP protease, putative
Authors:Mulichak, A., Loppnau, P., Bray, J., Amani, M., Vedadi, M., Wasney, G., Finerty, P., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., Hui, R., Plotnikova, O., Structural Genomics Consortium (SGC)
Deposit date:2005-11-29
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum.
J.Mol.Biol., 404, 2010
1HZM
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STRUCTURE OF ERK2 BINDING DOMAIN OF MAPK PHOSPHATASE MKP-3: STRUCTURAL INSIGHTS INTO MKP-3 ACTIVATION BY ERK2
Descriptor:DUAL SPECIFICITY PROTEIN PHOSPHATASE 6
Authors:Farooq, A., Zhou, M.-M.
Deposit date:2001-01-25
Release date:2002-01-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of ERK2 binding domain of MAPK phosphatase MKP-3: structural insights into MKP-3 activation by ERK2.
Mol.Cell, 7, 2001
1JSP
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NMR STRUCTURE OF CBP BROMODOMAIN IN COMPLEX WITH P53 PEPTIDE
Descriptor:tumor protein p53, CREB-BINDING PROTEIN
Authors:He, Y., Mujtaba, S., Zeng, L., Yan, S., Zhou, M.-M.
Deposit date:2001-08-17
Release date:2002-08-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
Mol.Cell, 13, 2004
1M3G
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SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF MAPK PHOSPHATASE PAC-1: INSIGHTS INTO SUBSTRATE-INDUCED ENZYMATIC ACTIVATION
Descriptor:DUAL SPECIFICITY PROTEIN PHOSPHATASE 2
Authors:Farooq, A., Zhou, M.-M.
Deposit date:2002-06-27
Release date:2003-06-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the MAPK Phosphatase PAC-1 Catalytic Domain Insights into Substrate-Induced Enzymatic Activation of MKP
Structure, 11, 2003
1TXJ
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CRYSTAL STRUCTURE OF TRANSLATIONALLY CONTROLLED TUMOUR-ASSOCIATED PROTEIN (TCTP) FROM PLASMODIUM KNOWLESI
Descriptor:translationally controlled tumour-associated protein (TCTP) from Plasmodium knowlesi, PKN_PFE0545c
Authors:Walker, J.R., Vedadi, M., Sharma, S., Houston, S., Lew, J., Amani, M., Wasney, G., Skarina, T., Bray, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Hui, R., Structural Genomics Consortium (SGC)
Deposit date:2004-07-05
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1XCC
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1-CYS PEROXIDOXIN FROM PLASMODIUM YOELLI
Descriptor:1-Cys peroxiredoxin
Authors:Vedadi, M., Sharma, S., Houston, S., Lew, J., Wasney, G., Amani, M., Xu, X., Bray, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Hui, R., Bochkarev, A., Structural Genomics Consortium (SGC)
Deposit date:2004-09-01
Release date:2004-11-09
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z6G
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CRYSTAL STRUCTURE OF GUANYLATE KINASE FROM PLASMODIUM FALCIPARUM
Descriptor:guanylate kinase, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Mulichak, A.M., Lew, J., Artz, J., Choe, J., Walker, J.R., Zhao, Y., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Gao, M., Structural Genomics Consortium (SGC)
Deposit date:2005-03-22
Release date:2005-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z7D
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ORNITHINE AMINOTRANSFERASE PY00104 FROM PLASMODIUM YOELII
Descriptor:ornithine aminotransferase
Authors:Walker, J.R., Alam, Z., Amani, M., Lew, J., Wasney, G., Boulanger, K., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Vedadi, M., Structural Genomics Consortium (SGC)
Deposit date:2005-03-24
Release date:2005-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z81
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CRYSTAL STRUCTURE OF CYCLOPHILIN FROM PLASMODIUM YOELII.
Descriptor:cyclophilin
Authors:Mulichak, A., Alam, Z., Amani, M., Lew, J., Wasney, G., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Vedadi, M., Structural Genomics Consortium (SGC)
Deposit date:2005-03-29
Release date:2005-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1ZO2
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STRUCTURE OF NUCLEAR TRANSPORT FACTOR 2 (NTF2) FROM CRYPTOSPORIDIUM PARVUM
Descriptor:nuclear transport factor 2
Authors:Choe, J., Artz, J.D., Gao, M., Lew, J., Zhao, Y., Arrowsmith, C., Edwards, A., Sundstrom, M., Bochkarev, A., Hui, R., Structural Genomics Consortium (SGC)
Deposit date:2005-05-12
Release date:2005-05-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2A22
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STRUCTURE OF VACUOLAR PROTEIN SORTING 29 FROM CRYPTOSPORIDIUM PARVUM
Descriptor:vacuolar protein sorting 29
Authors:Brokx, S., Zhao, Y., Alam, Z., Lew, J., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Walker, J.R., Structural Genomics Consortium (SGC)
Deposit date:2005-06-21
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2A4A
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DEOXYRIBOSE-PHOSPHATE ALDOLASE FROM P. YOELII
Descriptor:deoxyribose-phosphate aldolase
Authors:Walker, J.R., Amani, M., Lew, J., Wiegelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Vedadi, M., Structural Genomics Consortium (SGC)
Deposit date:2005-06-28
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AIF
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CRYSTAL STRUCTURE OF HIGH MOBILITY LIKE PROTEIN, NHP2, PUTATIVE FROM CRYPTOSPORIDIUM PARVUM
Descriptor:ribosomal protein L7A
Authors:Dong, A., Zhao, Y., Lew, J., Alam, Z., Melone, M., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Sundstrom, M., Hui, R., Bochkarev, A., Artz, J., Structural Genomics Consortium (SGC)
Deposit date:2005-07-29
Release date:2005-08-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AMX
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CRYSTAL STRUCTURE OF PLASMODIUM YOELII ADENOSINE DEAMINASE (PY02076)
Descriptor:adenosine deaminase, COBALT (II) ION, UNKNOWN ATOM OR ION
Authors:Dong, A., Vedadi, M., Wasney, G., Zhao, Y., Lew, J., Alam, Z., Melone, M., Koeieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2005-08-10
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AQW
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STRUCTURE OF PUTATIVE OROTIDINE-MONOPHOSPHATE-DECARBOXYLASE FROM PLASMODIUM YOELII (PY01515)
Descriptor:putative orotidine-monophosphate-decarboxylase, IODIDE ION, SULFATE ION
Authors:Dong, A., Vedadi, M., Wasney, G., Zhao, Y., Lew, J., Alam, Z., Melone, M., Koeieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2005-08-18
Release date:2005-08-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AV4
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CRYSTAL STRUCTURE OF PLASMODIUM YOELII THIOREDOXIN-LIKE PROTEIN 4A (DIM1)
Descriptor:Thioredoxin-like protein 4A (DIM1), CHLORIDE ION
Authors:Dong, A., Zhao, Y., Lew, J., Alam, Z., Melone, M., Wasney, G., Vedadi, M., Koeieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Artz, J., Structural Genomics Consortium (SGC)
Deposit date:2005-08-29
Release date:2005-09-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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