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1UWQ
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS
Descriptor:BETA-GALACTOSIDASE, ACETATE ION
Authors:Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
Deposit date:2004-02-11
Release date:2004-05-20
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.
Biochemistry, 43, 2004
1UWR
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH 2-DEOXY-2-FLUORO-GALACTOSE
Descriptor:BETA-GALACTOSIDASE, 2-DEOXY-2-FLUORO-ALPHA-D-GALACTOPYRANOSE, ACETATE ION
Authors:Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
Deposit date:2004-02-11
Release date:2004-05-20
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural Studies of the Beta-Glycosidase from Sulfolobus Solfataricus in Complex with Covalently and Noncovalently Bound Inhibitors.
Biochemistry, 43, 2004
1UWS
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH 2-DEOXY-2-FLUORO-GLUCOSE
Descriptor:BETA-GALACTOSIDASE, 2-deoxy-2-fluoro-alpha-D-glucopyranose, ACETATE ION
Authors:Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
Deposit date:2004-02-11
Release date:2004-05-20
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.
Biochemistry, 43, 2004
1UWT
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH D-GALACTOHYDROXIMO-1,5-LACTAM
Descriptor:BETA-GALACTOSIDASE, (2E,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)-2-PIPERIDINONE, ACETATE ION
Authors:Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
Deposit date:2004-02-11
Release date:2004-05-20
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.
Biochemistry, 43, 2004
1UWU
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH D-GLUCOHYDROXIMO-1,5-LACTAM
Descriptor:BETA-GALACTOSIDASE, (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, ACETATE ION
Authors:Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
Deposit date:2004-02-11
Release date:2004-05-20
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.
Biochemistry, 43, 2004
4BHB
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS O6-METHYLGUANINE METHYLTRANSFERASE
Descriptor:METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE, GLYCEROL
Authors:Miggiano, R., Casazza, V., Garavaglia, S., Ciaramella, M., Perugino, G., Rizzii, M., Rossi, F.
Deposit date:2013-04-02
Release date:2013-04-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical and Structural Studies of the Mycobacterium Tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants.
J.Bacteriol., 195, 2013
4BHC
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CRYSTAL STRUCTURE OF THE M. TUBERCULOSIS O6-METHYLGUANINE METHYLTRANSFERASE R37L VARIANT
Descriptor:METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE
Authors:Miggiano, R., Casazza, V., Garavaglia, S., Ciaramella, M., Perugino, G., Rizzi, M., Rossi, F.
Deposit date:2013-04-02
Release date:2013-04-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biochemical and Structural Studies on the M. Tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants.
J.Bacteriol., 195, 2013
4ZYD
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CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS O6-METHYLGUANINE METHYLTRANSFERASE IN COMPLEX WITH MODIFIED DNA
Descriptor:Methylated-DNA--protein-cysteine methyltransferase, DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3')
Authors:Miggiano, R., Rossi, F., Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Method:X-RAY DIFFRACTION (2.682 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYE
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CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS O6-METHYLGUANINE METHYLTRANSFERASE
Descriptor:Methylated-DNA--protein-cysteine methyltransferase, GLYCEROL, NITRATE ION
Authors:Miggiano, R., Rossi, F., Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYG
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CRYSTAL STRUCTURE OF METHYLATED SULFOLOBUS SOLFATARICUS O6-METHYLGUANINE METHYLTRANSFERASE
Descriptor:Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R., Rossi, F., Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYH
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CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS O6-METHYLGUANINE METHYLTRANSFERASE C119L VARIANT
Descriptor:Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R., Rossi, F., Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
5LLQ
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CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS O6-METHYLGUANINE METHYLTRANSFERASE C119F VARIANT
Descriptor:Methylated-DNA--protein-cysteine methyltransferase, GLYCEROL
Authors:Miggiano, R., Rossi, F., Rizzi, M.
Deposit date:2016-07-28
Release date:2016-11-09
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.
Biochim.Biophys.Acta, 1861, 2016
2CEQ
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BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH GLUCOIMIDAZOLE
Descriptor:BETA-GALACTOSIDASE, ACETATE ION, GLUCOIMIDAZOLE
Authors:Gloster, T.M., Moracci, M., Vasella, A., Davies, G.J.
Deposit date:2006-02-10
Release date:2006-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.
Biochemistry, 45, 2006
2CER
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BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH PHENETHYL-SUBSTITUTED GLUCOIMIDAZOLE
Descriptor:BETA-GLUCOSIDASE A, (5R,6R,7S,8S)-5-(HYDROXYMETHYL)-2-(2-PHENYLETHYL)-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, ACETATE ION
Authors:Gloster, T.M., Roberts, S., Moracci, M., Vasella, A., Davies, G.J.
Deposit date:2006-02-10
Release date:2006-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.
Biochemistry, 45, 2006
2CES
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BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH GLUCOIMIDAZOLE
Descriptor:BETA-GLUCOSIDASE A, ACETATE ION, GLUCOIMIDAZOLE, ...
Authors:Gloster, T.M., Roberts, S., Vasella, A., Davies, G.J.
Deposit date:2006-02-10
Release date:2006-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.
Biochemistry, 45, 2006
2CET
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BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH PHENETHYL- SUBSTITUTED GLUCOIMIDAZOLE
Descriptor:BETA-GLUCOSIDASE A, ACETATE ION, (5R,6R,7S,8S)-5-(HYDROXYMETHYL)-2-(2-PHENYLETHYL)-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, ...
Authors:Gloster, T.M., Roberts, S., Vasella, A., Davies, G.J.
Deposit date:2006-02-10
Release date:2006-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.
Biochemistry, 45, 2006
4WX9
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS OGT IN COMPLEX WITH DNA
Descriptor:DNA (5'-D(*GP*CP*CP*AP*TP*GP*(E1X)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'), Methylated-DNA--protein-cysteine methyltransferase, ...
Authors:Miggiano, R., Rossi, F., Garavaglia, S., Rizzi, M.
Deposit date:2014-11-13
Release date:2015-11-04
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.
Biochem.J., 473, 2016
4WXC
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS OGT-Y139F
Descriptor:Methylated-DNA--protein-cysteine methyltransferase, 1,2-ETHANEDIOL
Authors:Miggiano, R., Rossi, F., Garavaglia, S., Rizzi, M.
Deposit date:2014-11-13
Release date:2015-11-04
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.
Biochem.J., 473, 2016
4WXD
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS OGT-R37K
Descriptor:Methylated-DNA--protein-cysteine methyltransferase, GLYCEROL
Authors:Miggiano, R., Rossi, F., Garavaglia, S., Rizzi, M.
Deposit date:2014-11-13
Release date:2015-11-04
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.
Biochem.J., 473, 2016
6GA0
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CRYSTAL STRUCTURE OF A THERMOPHILIC O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE-DERIVED SELF-LABELING PROTEIN-TAG IN COVALENT COMPLEX WITH SNAP-VISTA GREEN
Descriptor:Methylated-DNA--protein-cysteine methyltransferase, 5-[(4-methylphenyl)methylcarbamoyl]-2-(6-oxidanyl-3-oxidanylidene-4~{H}-xanthen-9-yl)benzoic acid, SULFATE ION
Authors:Miggiano, R., Rossi, F., Rizzi, M.
Deposit date:2018-04-11
Release date:2018-05-09
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe.
Biochem. Biophys. Res. Commun., 500, 2018