Author results

1BSJ
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COBALT DEFORMYLASE INHIBITOR COMPLEX FROM E.COLI
Descriptor:PROTEIN (PEPTIDE DEFORMYLASE), COBALT (II) ION, PHOSPHATE ION, ...
Authors:Hao, B., Gong, W., Rajagopalan, P.T., Hu, Y., Pei, D., Chan, M.K.
Deposit date:1998-08-28
Release date:2000-04-15
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the design of antibiotics targeting peptide deformylase.
Biochemistry, 38, 1999
1BSK
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ZINC DEFORMYLASE INHIBITOR COMPLEX FROM E.COLI
Descriptor:PROTEIN (PEPTIDE DEFORMYLASE), ZINC ION, PHOSPHATE ION, ...
Authors:Hao, B., Gong, W., Rajagopalan, P.T., Hu, Y., Pei, D., Chan, M.K.
Deposit date:1998-08-28
Release date:2000-04-15
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the design of antibiotics targeting peptide deformylase.
Biochemistry, 38, 1999
1JYM
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CRYSTALS OF PEPTIDE DEFORMYLASE FROM PLASMODIUM FALCIPARUM WITH TEN SUBUNITS PER ASYMMETRIC UNIT REVEAL CRITICAL CHARACTERISTICS OF THE ACTIVE SITE FOR DRUG DESIGN
Descriptor:Peptide Deformylase, COBALT (II) ION
Authors:Kumar, A., Nguyen, K.T., Srivathsan, S., Ornstein, B., Turley, S., Hirsh, I., Pei, D., Hol, W.G.J.
Deposit date:2001-09-12
Release date:2002-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design.
Structure, 10, 2002
1RL4
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PLASMODIUM FALCIPARUM PEPTIDE DEFORMYLASE COMPLEX WITH INHIBITOR
Descriptor:formylmethionine deformylase, COBALT (II) ION, (2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID, ...
Authors:Robien, M.A., Nguyen, K.T., Kumar, A., Hirsh, I., Turley, S., Pei, D., Hol, W.G.J.
Deposit date:2003-11-24
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:An improved crystal form of Plasmodium falciparum peptide deformylase.
Protein Sci., 13, 2004
1RQC
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CRYSTALS OF PEPTIDE DEFORMYLASE FROM PLASMODIUM FALCIPARUM WITH TEN SUBUNITS PER ASYMMETRIC UNIT REVEAL CRITICAL CHARACTERISTICS OF THE ACTIVE SITE FOR DRUG DESIGN
Descriptor:formylmethionine deformylase, COBALT (II) ION
Authors:Robien, M.A., Nguyen, K.T., Kumar, A., Hirsh, I., Turley, S., Pei, D., Hol, W.G.
Deposit date:2003-12-04
Release date:2004-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An improved crystal form of Plasmodium falciparum peptide deformylase
Protein Sci., 13, 2004
1DFF
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PEPTIDE DEFORMYLASE
Descriptor:PEPTIDE DEFORMYLASE, ZINC ION
Authors:Chan, M.K., Gong, W., Rajagopalan, P.T.R., Hao, B., Tsai, C.M., Pei, D.
Deposit date:1997-08-19
Release date:1998-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Crystal structure of the Escherichia coli peptide deformylase.
Biochemistry, 36, 1997
1YCL
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CRYSTAL STRUCTURE OF B. SUBTILIS LUXS IN COMPLEX WITH A CATALYTIC 2-KETONE INTERMEDIATE
Descriptor:S-ribosylhomocysteinase, COBALT (II) ION, SULFATE ION, ...
Authors:Rajan, R., Zhu, J., Hu, X., Pei, D., Bell, C.E.
Deposit date:2004-12-22
Release date:2005-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of S-Ribosylhomocysteinase (LuxS) in Complex with a Catalytic 2-Ketone Intermediate.
Biochemistry, 44, 2005
2FQO
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CRYSTAL STRUCTURE OF B. SUBTILIS LUXS IN COMPLEX WITH (2S)-2-AMINO-4-[(2R,3R)-2,3-DIHYDROXY-3-N- HYDROXYCARBAMOYL-PROPYLMERCAPTO]BUTYRIC ACID
Descriptor:S-ribosylhomocysteine lyase, COBALT (II) ION, SULFATE ION, ...
Authors:Shen, G., Rajan, R., Zhu, J., Bell, C.E., Pei, D.
Deposit date:2006-01-18
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Design and Synthesis of Substrate and Intermediate Analogue Inhibitors of S-Ribosylhomocysteinase
J.Med.Chem., 49, 2006
2FQT
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CRYSTAL STRUCTURE OF B.SUBTILIS LUXS IN COMPLEX WITH (2S)-2-AMINO-4-[(2R,3S)-2,3-DIHYDROXY-3-N-HYDROXYCARBAMOYL-PROPYLMERCAPTO]BUTYRIC ACID
Descriptor:S-ribosylhomocysteine lyase, SULFATE ION, COBALT (II) ION, ...
Authors:Shen, G., Rajan, R., Zhu, J., Bell, C.E., Pei, D.
Deposit date:2006-01-18
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Design and Synthesis of Substrate Analogue Inhibitors of S-Ribosylhomocysteinase (LuxS)
J.Med.Chem., 49, 2006
3TKZ
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STRUCTURE OF THE SHP-2 N-SH2 DOMAIN IN A 1:2 COMPLEX WITH RVIPYFVPLNR PEPTIDE
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, PROTEIN (RVIpYFVPLNR peptide)
Authors:Zhang, Y., Zhang, J., Yuan, C., Hard, R.L., Park, I.H., Li, C., Bell, C.E., Pei, D.
Deposit date:2011-08-29
Release date:2011-10-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50, 2011
3TL0
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STRUCTURE OF SHP2 N-SH2 DOMAIN IN COMPLEX WITH RLNPYAQLWHR PEPTIDE
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, RLNpYAQLWHR peptide, SULFATE ION
Authors:Zhang, Y., Zhang, J., Yuan, C., Hard, R.L., Park, I.H., Li, C., Bell, C.E., Pei, D.
Deposit date:2011-08-29
Release date:2011-09-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50, 2011
4ZRT
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PTP1BC215S BOUND TO NEPHRIN PEPTIDE SUBSTRATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, GLY-PRO-LEU-PTR-ASP-GLU, MAGNESIUM ION, ...
Authors:Selner, N.G., Bell, C.E., Pei, D.
Deposit date:2015-05-12
Release date:2015-06-24
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Diverse levels of sequence selectivity and catalytic efficiency of protein-tyrosine phosphatases.
Biochemistry, 53, 2014
1G3G
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NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53
Descriptor:PROTIEN KINASE SPK1
Authors:Yuan, C., Liao, H., Su, M., Yongkiettrakul, S., Byeon, I.-J.L., Tsai, M.-D.
Deposit date:2000-10-24
Release date:2001-01-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9
J.Mol.Biol., 304, 2000
1WOF
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CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Rao, Z.
Deposit date:2004-08-18
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMD
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CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N9
Descriptor:3C-like proteinase, N-(3-FUROYL)-D-VALYL-L-VALYL-N~1~-((1R,2Z)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-D-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-09
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMP
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CRYSTAL STRUCTURE OF PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS MPRO IN COMPLEX WITH AN INHIBITOR N1
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-10
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMQ
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CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N3
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-10
Release date:2005-09-13
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2D2D
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CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR I2
Descriptor:3C-like proteinase, ETHYL (2E,4S)-4-[((2R)-2-{[N-(TERT-BUTOXYCARBONYL)-L-VALYL]AMINO}-2-PHENYLETHANOYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENT-2-ENOATE
Authors:Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Ding, Y., Rao, Z.
Deposit date:2005-09-08
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
1FHQ
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REFINED SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53
Descriptor:PROTEIN KINASE SPK1
Authors:Byeon, I.-J.L., Liao, H., Tsai, M.-D.
Deposit date:2000-08-02
Release date:2000-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
J.Mol.Biol., 302, 2000
1FHR
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SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE
Descriptor:PROTEIN KINASE SPK1, DNA REPAIR PROTEIN RAD9
Authors:Byeon, I.-J.L., Liao, H., Yongkiettrakul, S., Tsai, M.-D.
Deposit date:2000-08-02
Release date:2000-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
J.Mol.Biol., 302, 2000
4ON3
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CRYSTAL STRUCTURE OF HUMAN SORTING NEXIN 10 (SNX10)
Descriptor:Sorting nexin-10, NITRATE ION, PENTAETHYLENE GLYCOL, ...
Authors:Xu, T., Xu, J., Wang, Q., Liu, J.
Deposit date:2014-01-28
Release date:2014-09-24
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis.
Proteins, 82, 2014
4PZG
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CRYSTAL STRUCTURE OF HUMAN SORTING NEXIN 10 (SNX10)
Descriptor:Sorting nexin-10, NITRATE ION, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL
Authors:Xu, T., Xu, J., Wang, Q., Liu, J.
Deposit date:2014-03-30
Release date:2014-09-24
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis.
Proteins, 82, 2014
5GW0
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CRYSTAL STRUCTURE OF SNX16 PX-COILED COIL
Descriptor:Sorting nexin-16
Authors:Xu, J., Liu, J.
Deposit date:2016-09-08
Release date:2017-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding.
Structure, 25, 2017
5GW1
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CRYSTAL STRUCTURE OF SNX16 PX-COILED COIL IN SPACE GROUP P212121
Descriptor:Sorting nexin-16
Authors:Xu, J., Liu, J.
Deposit date:2016-09-08
Release date:2017-09-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding.
Structure, 25, 2017
6M9K
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CRYSTAL STRUCTURE OF LAMBDA EXONUCLEASE IN COMPLEX WITH THE RED BETA C-TERMINAL DOMAIN
Descriptor:Exonuclease, Recombination protein bet, SULFATE ION
Authors:Bell, C.E., Caldwell, B.J.
Deposit date:2018-08-23
Release date:2019-01-02
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Red beta C-terminal domain in complex with lambda Exonuclease reveals an unexpected homology with lambda Orf and an interaction with Escherichia coli single stranded DNA binding protein.
Nucleic Acids Res., 47, 2019
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