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1A41
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TYPE 1-TOPOISOMERASE CATALYTIC FRAGMENT FROM VACCINIA VIRUS
Descriptor:TOPOISOMERASE I, SULFATE ION
Authors:Cheng, C., Kussie, P., Pavletich, N., Shuman, S.
Deposit date:1998-02-10
Release date:1999-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases.
Cell(Cambridge,Mass.), 92, 1998
1MQB
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CRYSTAL STRUCTURE OF EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE
Descriptor:Ephrin type-A receptor 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Nowakowski, J., Cronin, C.N., McRee, D.E., Knuth, M.W., Nelson, C., Pavletich, N., Rogers, J., Sang, B.C., Scheibe, D.N., Swanson, R.V., Thompson, D.A.
Deposit date:2002-09-16
Release date:2003-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the Cancer Related Aurora-A, FAK and EphA2 Protein Kinases from Nanovolume Crystallography
Structure, 10, 2003
1TSR
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P53 CORE DOMAIN IN COMPLEX WITH DNA
Descriptor:DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR), ...
Authors:Cho, Y., Gorina, S., Jeffrey, P., Pavletich, N.
Deposit date:1995-07-28
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
4LYN
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CRYSTAL STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2-WT) COMPLEX WITH (2S)-N-(5-(((5-TERT-BUTYL-1,3-OXAZOL-2-YL)METHYL)SULFANYL)-1,3-THIAZOL-2-YL)-2-PHENYLPROPANAMIDE
Descriptor:Cyclin-dependent kinase 2, (2S)-N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)-2-phenylpropanamide
Authors:Sack, J.S.
Deposit date:2013-07-31
Release date:2013-10-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-Ray Crystallographic Analysis, and Biological Activities
J.Med.Chem., 45, 2002