Author results

1EJM
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CRYSTAL STRUCTURE OF THE BPTI ALA16LEU MUTANT IN COMPLEX WITH BOVINE TRYPSIN
Descriptor:BETA-TRYPSIN, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION
Authors:Otlewski, J., Smalas, A., Helland, R., Grzesiak, A., Krowarsch, D.
Deposit date:2000-03-03
Release date:2001-03-03
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Substitutions at the P(1) position in BPTI strongly affect the association energy with serine proteinases.
J.Mol.Biol., 301, 2000
1T7C
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CRYSTAL STRUCTURE OF THE P1 GLU BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor:Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H., Helland, R., Otlewski, J., Smalas, A.O.
Deposit date:2004-05-09
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1T8L
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CRYSTAL STRUCTURE OF THE P1 MET BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor:Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H., Helland, R., Otlewski, J., Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1T8M
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CRYSTAL STRUCTURE OF THE P1 HIS BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor:Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H., Helland, R., Otlewski, J., Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1T8N
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CRYSTAL STRUCTURE OF THE P1 THR BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor:Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H., Helland, R., Otlewski, J., Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1T8O
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CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor:Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H., Helland, R., Otlewski, J., Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1G6X
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ULTRA HIGH RESOLUTION STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI) MUTANT WITH ALTERED BINDING LOOP SEQUENCE
Descriptor:PANCREATIC TRYPSIN INHIBITOR, SULFATE ION, 1,2-ETHANEDIOL
Authors:Addlagatta, A., Czapinska, H., Krzywda, S., Otlewski, J., Jaskolski, M.
Deposit date:2000-11-08
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.86 Å)
Cite:Ultrahigh-resolution structure of a BPTI mutant.
Acta Crystallogr.,Sect.D, 57, 2001
1HCD
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STRUCTURE OF HISACTOPHILIN IS SIMILAR TO INTERLEUKIN-1 BETA AND FIBROBLAST GROWTH FACTOR
Descriptor:HISACTOPHILIN
Authors:Habazettl, J., Gondol, D., Wiltscheck, R., Otlewski, J., Schleicher, M., Holak, T.A.
Deposit date:1994-05-03
Release date:1994-10-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of hisactophilin is similar to interleukin-1 beta and fibroblast growth factor.
Nature, 359, 1992
1HCE
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STRUCTURE OF HISACTOPHILIN IS SIMILAR TO INTERLEUKIN-1 BETA AND FIBROBLAST GROWTH FACTOR
Descriptor:HISACTOPHILIN
Authors:Habazettl, J., Gondol, D., Wiltscheck, R., Otlewski, J., Schleicher, M., Holak, T.A.
Deposit date:1994-07-12
Release date:1994-09-30
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of hisactophilin is similar to interleukin-1 beta and fibroblast growth factor.
Nature, 359, 1992
1CTI
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DETERMINATION OF THE COMPLETE THREE-DIMENSIONAL STRUCTURE OF THE TRYPSIN INHIBITOR FROM SQUASH SEEDS IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE AND A COMBINATION OF DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING
Descriptor:TRYPSIN INHIBITOR
Authors:Holak, T.A., Gondol, D., Otlewski, J., Wilusz, T.
Deposit date:1990-08-28
Release date:1992-01-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing.
J.Mol.Biol., 210, 1989
1LD5
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STRUCTURE OF BPTI MUTANT A16V
Descriptor:PANCREATIC TRYPSIN INHIBITOR
Authors:Cierpicki, T., Otlewski, J.
Deposit date:2002-04-08
Release date:2002-09-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability.
J.Mol.Biol., 321, 2002
1LD6
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STRUCTURE OF BPTI_8A MUTANT
Descriptor:PANCREATIC TRYPSIN INHIBITOR
Authors:Cierpicki, T., Otlewski, J.
Deposit date:2002-04-08
Release date:2002-09-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability.
J.Mol.Biol., 321, 2002
1MJD
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STRUCTURE OF N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor:DOUBLECORTIN
Authors:Kim, M.H., Cierpicki, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Z., Walsh, C.A., Otlewski, J., Bushweller, J.H., Derewenda, Z.S.
Deposit date:2002-08-27
Release date:2003-04-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
2CTI
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DETERMINATION OF THE COMPLETE THREE-DIMENSIONAL STRUCTURE OF THE TRYPSIN INHIBITOR FROM SQUASH SEEDS IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE AND A COMBINATION OF DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING
Descriptor:TRYPSIN INHIBITOR
Authors:Holak, T.A., Gondol, D., Otlewski, J., Wilusz, T.
Deposit date:1990-08-28
Release date:1992-01-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing.
J.Mol.Biol., 210, 1989
1CCV
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NMR SOLUTION STRUCTURE OF APIS MELLIFERA CHYMOTRYPSIN INHIBITOR (AMCI).
Descriptor:CHYMOTRYPSIN INHIBITOR
Authors:Cierpicki, T., Otlewski, J.
Deposit date:1999-03-02
Release date:1999-03-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of Apis mellifera chymotrypsin/cathepsin G inhibitor-1 (AMCI-1): structural similarity with Ascaris protease inhibitors
Protein Sci., 9, 2000
1QLQ
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BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI) MUTANT WITH ALTERED BINDING LOOP SEQUENCE
Descriptor:PANCREATIC TRYPSIN INHIBITOR, SULFATE ION
Authors:Czapinska, H., Krzywda, S., Sheldrick, G.M., Otlewski, J., Jaskolski, M.
Deposit date:1999-09-10
Release date:1999-10-05
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:High Resolution Structure of Bovine Pancreatic Trypsin Inhibitor with Altered Binding Loop Sequence
J.Mol.Biol., 295, 1999
1XCG
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CRYSTAL STRUCTURE OF HUMAN RHOA IN COMPLEX WITH DH/PH FRAGMENT OF PDZRHOGEF
Descriptor:Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Derewenda, U., Oleksy, A., Stevenson, A.S., Korczynska, J., Dauter, Z., Somlyo, A.P., Otlewski, J., Somlyo, A.V., Derewenda, Z.S.
Deposit date:2004-09-01
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle
Structure, 12, 2004
1DWM
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SOLUTION STRUCTURE OF LINUM USITATISSINUM TRYPSIN INHIBITOR (LUTI)
Descriptor:LINUM USITATISSINUM TRYPSIN INHIBITOR
Authors:Cierpicki, T., Otlewski, J.
Deposit date:1999-12-08
Release date:1999-12-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Determination of a High Precision Structure of a Novel Protein, Linum Usitatissimum Trypsin Inhibitor (Luti), Using Computer-Aided Assignment of Noesy Cross-Peaks
J.Mol.Biol., 302, 2000
1KLL
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MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE
Descriptor:mitomycin-binding protein, 1,2-CIS-1-HYDROXY-2,7-DIAMINO-MITOSENE
Authors:Martin, T.W., Dauter, Z., Devedjiev, Y., Sheffield, P., Jelen, F., He, M., Sherman, D., Otlewski, J., Derewenda, Z.S., Derewenda, U.
Deposit date:2001-12-12
Release date:2002-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
1KMT
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CRYSTAL STRUCTURE OF RHOGDI GLU(154,155)ALA MUTANT
Descriptor:Rho GDP-dissociation inhibitor 1
Authors:Mateja, A., Devedjiev, Y., Krowarsh, D., Longenecker, K., Dauter, Z., Otlewski, J., Derewenda, Z.S.
Deposit date:2001-12-17
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The impact of Glu-->Ala and Glu-->Asp mutations on the crystallization properties of RhoGDI: the structure of RhoGDI at 1.3 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002
1KMZ
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MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE
Descriptor:mitomycin-binding protein
Authors:Martin, T.W., Dauter, Z., Devedjiev, Y., Sheffield, P., Jelen, F., He, M., Sherman, D., Otlewski, J., Derewenda, Z.S., Derewenda, U.
Deposit date:2001-12-17
Release date:2002-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
1MFW
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STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: SELENOMETHIONINE LABELED PROTEIN
Descriptor:DOUBLECORTIN-LIKE KINASE (N-TERMINAL DOMAIN), SULFATE ION
Authors:Kim, M.H., Cierpickil, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Z., Walsh, C.A., Otlewski, J., Bushweller, J.H., Derewenda, Z.
Deposit date:2002-08-13
Release date:2003-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
1MG4
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STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: WILD TYPE PROTEIN
Descriptor:DOUBLECORTIN-LIKE KINASE (N-TERMINAL DOMAIN), SULFATE ION
Authors:Kim, M.H., Cierpickil, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Z., Walsh, C.A., Otlewski, J., Bushweller, J.H., Derewenda, Z.
Deposit date:2002-08-14
Release date:2003-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.504 Å)
Cite:The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
1N99
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CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN
Descriptor:Syntenin 1
Authors:Kang, B.S., Cooper, D.R., Jelen, F., Devedjiev, Y., Derewenda, U., Dauter, Z., Otlewski, J., Derewenda, Z.S.
Deposit date:2002-11-22
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:PDZ Tandem of Human Syntenin: Crystal Structure and Functional Properties
Structure, 11, 2003
1P2I
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STRUCTURAL CONSEQUENCES OF ACCOMMODATION OF FOUR NON-COGNATE AMINO-ACID RESIDUES IN THE S1 POCKET OF BOVINE TRYPSIN AND CHYMOTRYPSIN
Descriptor:Trypsinogen, cationic, Pancreatic trypsin inhibitor, ...
Authors:Helland, R., Czapinska, H., Leiros, I., Olufsen, M., Otlewski, J., Smalaas, A.O.
Deposit date:2003-04-15
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
J.Mol.Biol., 333, 2003