Author results

1NEG
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CRYSTAL STRUCTURE ANALYSIS OF N-AND C-TERMINAL LABELED SH3-DOMAIN OF ALPHA-CHICKEN SPECTRIN
分子名称:Spectrin alpha chain, brain, AZIDE ION
著者Mueller, U., Buessow, K., Diehl, A., Niesen, F.H., Nyarsik, L., Heinemann, U.
登録日2002-12-11
公開日2003-01-14
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags
J.STRUCT.FUNCT.GENOM., 4, 2003
1SAW
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X-RAY STRUCTURE OF HOMO SAPIENS PROTEIN FLJ36880
分子名称:hypothetical protein FLJ36880, MAGNESIUM ION, CHLORIDE ION
著者Manjasetty, B.A., Niesen, F.H., Delbrueck, H., Goetz, F., Sievert, V., Buessow, K., Behlke, J., Heinemann, U.
登録日2004-02-09
公開日2004-10-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880.
Biol.Chem., 385, 2004
1U2H
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X-RAY STRUCTURE OF THE N-TERMINALLY TRUNCATED HUMAN APEP-1
分子名称:Aortic preferentially expressed protein 1
著者Manjasetty, B.A., Scheich, C., Roske, Y., Niesen, F.H., Gotz, F., Bussow, K., Heinemann, U.
登録日2004-07-19
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1)
Bmc Struct.Biol., 5, 2005
1Z57
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CRYSTAL STRUCTURE OF HUMAN CLK1 IN COMPLEX WITH 10Z-HYMENIALDISINE
分子名称:Dual specificity protein kinase CLK1, DEBROMOHYMENIALDISINE
著者Debreczeni, J., Das, S., Knapp, S., Bullock, A., Guo, K., Amos, A., Fedorov, O., Edwards, A., Sundstrom, M., von Delft, F., Niesen, F.H., Ball, L., Sobott, F., Arrowsmith, C., Structural Genomics Consortium (SGC)
登録日2005-03-17
公開日2005-04-12
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
Structure, 17, 2009
2IW2
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CRYSTAL STRUCTURE OF HUMAN PROLIDASE
分子名称:XAA-PRO DIPEPTIDASE, SODIUM ION
著者Mueller, U., Niesen, F.H., Roske, Y., Goetz, F., Behlke, J., Buessow, K., Heinemann, U.
登録日2006-06-24
公開日2006-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal Structure of Human Prolidase: The Molecular Basis of Pd Disease
To be Published
2J1L
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CRYSTAL STRUCTURE OF HUMAN RHO-RELATED GTP-BINDING PROTEIN RHOD
分子名称:RHO-RELATED GTP-BINDING PROTEIN RHOD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Pike, A.C.W., Johansson, C., Gileadi, C., Niesen, F.H., Sobott, F., Schoch, G., Elkins, J., Smee, C., Gorrec, F., Watt, S., Bray, J., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2006-08-14
公開日2006-09-18
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod
To be Published
2JAM
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE I G
分子名称:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G, POLYPEPTIDE, 1,2-ETHANEDIOL, ...
著者Debreczeni, J.E., Bullock, A., Keates, T., Niesen, F.H., Salah, E., Shrestha, L., Smee, C., Sobott, F., Pike, A.C.W., Bunkoczi, G., von Delft, F., Turnbull, A., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Knapp, S.
登録日2006-11-29
公開日2007-03-13
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G
To be Published
2JC6
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE 1D
分子名称:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D, N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
著者Debreczeni, J.E., Rellos, P., Fedorov, O., Niesen, F.H., Bhatia, C., Shrestha, L., Salah, E., Smee, C., Colebrook, S., Berridge, G., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Pike, A.C.W., von Delft, F., Knapp, S., Sundstrom, M., Weigelt, J., Arrowsmith, C.H., Edwards, A.
登録日2006-12-19
公開日2007-02-13
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Human Calmodulin-Dependent Protein Kinase 1D
To be Published
2JIF
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STRUCTURE OF HUMAN SHORT-BRANCHED CHAIN ACYL-COA DEHYDROGENASE (ACADSB)
分子名称:SHORT/BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE, COENZYME A PERSULFIDE, ...
著者Pike, A.C.W., Hozjan, V., Smee, C., Niesen, F.H., Kavanagh, K.L., Umeano, C., Turnbull, A.P., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Oppermann, U.
登録日2007-02-28
公開日2007-04-03
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Human Short-Branched Chain Acyl-Coa Dehydrogenase
To be Published
2OKN
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CRYSTAL STRCTURE OF HUMAN PROLIDASE
分子名称:Xaa-Pro dipeptidase, MANGANESE (II) ION, HYDROGENPHOSPHATE ION
著者Mueller, U., Niesen, F.H., Roske, Y., Goetz, F., Behlke, J., Buessow, K., Heinemann, U., Protein Structure Factory (PSF)
登録日2007-01-17
公開日2007-02-20
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of Human Prolidase: The Molecular Basis of PD Disease.
To be Published
2P0A
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THE CRYSTAL STRUCTURE OF HUMAN SYNAPSIN III (SYN3) IN COMPLEX WITH AMPPNP
分子名称:Synapsin-3, CHLORIDE ION, SULFATE ION, ...
著者Turnbull, A.P., Phillips, C., Pike, A.C.W., Elkins, J.M., Gileadi, C., Salah, E., Niesen, F.H., Burgess, N., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2007-02-28
公開日2007-03-27
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of human synapsin III (SYN3) in complex with AMPPNP
To be Published
2UYY
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STRUCTURE OF THE CYTOKINE-LIKE NUCLEAR FACTOR N-PAC
分子名称:N-PAC PROTEIN, POTASSIUM ION, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
著者Tickle, J., Pilka, E.S., Bunkoczi, G., Berridge, G., Smee, C., Kavanagh, K.L., Hozjan, V., Niesen, F.H., Papagrigoriou, E., Pike, A.C.W., Turnbull, A., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., von Delft, F., Oppermann, U.
登録日2007-04-20
公開日2007-07-03
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Structure of the Cytokine-Like Nuclear Factor N-Pac
To be Published
2GDZ
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CRYSTAL STRUCTURE OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE TYPE1, COMPLEXED WITH NAD+
分子名称:NAD+-dependent 15-hydroxyprostaglandin dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Pilka, E.S., Guo, K., Kavanagh, K., Von Delft, F., Arrowsmith, C., Weigelt, J., Edwards, A., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-03-17
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献High-Affinity Inhibitors of Human NAD-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships.
Plos One, 5, 2010
1ONI
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CRYSTAL STRUCTURE OF A HUMAN P14.5, A TRANSLATIONAL INHIBITOR REVEALS DIFFERENT MODE OF LIGAND BINDING NEAR THE INVARIANT RESIDUES OF THE YJGF/UK114 PROTEIN FAMILY
分子名称:14.5 kDa translational inhibitor protein, BENZOIC ACID
著者Manjasetty, B.A., Delbrueck, H., Mueller, U., Erdmann, M.F., Heinemann, U.
登録日2003-02-28
公開日2003-04-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Homo sapiens protein hp14.5.
Proteins, 54, 2004
1SZ7
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CRYSTAL STRUCTURE OF HUMAN BET3
分子名称:Trafficking protein particle complex subunit 3, PALMITIC ACID
著者Turnbull, A.P., Prinz, B., Holz, C., Behlke, J., Schultchen, J., Delbrueck, H., Niesen, F.H., Lang, C., Heinemann, U.
登録日2004-04-05
公開日2005-01-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization
Embo J., 24, 2005
1XCR
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CRYSTAL STRUCTURE OF LONGER SPLICE VARIANT OF PTD012 FROM HOMO SAPIENS REVEALS A NOVEL ZINC-CONTAINING FOLD
分子名称:hypothetical protein PTD012, ZINC ION, ACETIC ACID
著者Manjasetty, B.A., Fieber-Erdmann, M., Roske, Y., Goetz, F., Buessow, K., Heinemann, U.
登録日2004-09-03
公開日2005-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold
Protein Sci., 15, 2006
1ZV4
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STRUCTURE OF THE REGULATOR OF G-PROTEIN SIGNALING 17 (RGSZ2)
分子名称:Regulator of G-protein signaling 17
著者Schoch, G.A., Jansson, A., Elkins, J.M., Haroniti, A., Niesen, F.H., Bunkoczi, G., Lee, W.H., Turnbull, A.P., Yang, X., Sundstrom, M., Arrowsmith, C., Edwards, A., Marsden, B., Gileadi, O., Ball, L., von Delft, F., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-06-01
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2EU9
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CRYSTAL STRUCTURE OF CLK3
分子名称:Dual specificity protein kinase CLK3, 1,2-ETHANEDIOL
著者Papagrigoriou, E., Rellos, P., Das, S., Ugochukwu, E., Turnbull, A., von Delft, F., Bunkoczi, G., Sobott, F., Bullock, A., Fedorov, O., Gileadi, C., Savitsky, P., Edwards, A., Aerrowsmith, C., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2005-10-28
公開日2005-11-08
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
Structure, 17, 2009
2J51
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CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE BOUND TO 5-AMINO-3-((4-(AMINOSULFONYL)PHENYL)AMINO) -N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE- 1-CARBOTHIOAMIDE
分子名称:STE20-LIKE SERINE/THREONINE-PROTEIN KINASE, 1,2-ETHANEDIOL, THIOCYANATE ION, ...
著者Pike, A.C.W., Rellos, P., Fedorov, O., Keates, T., Salah, E., Savitsky, P., Papagrigoriou, E., Turnbull, A.P., Debreczeni, J.E., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2006-09-08
公開日2006-10-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
2J7T
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CRYSTAL STRUCTURE OF HUMAN SERINE THREONINE KINASE-10 BOUND TO SU11274
分子名称:SERINE/THREONINE-PROTEIN KINASE 10, CALCIUM ION, ACETATE ION, ...
著者Pike, A.C.W., Rellos, P., Fedorov, O., Das, S., Debreczeni, J., Sobott, F., Watt, S., Savitsky, P., Eswaran, J., Turnbull, A.P., Papagrigoriou, E., Ugochukwa, E., Gorrec, F., Umeano, C.C., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2006-10-17
公開日2006-11-07
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
2J90
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CRYSTAL STRUCTURE OF HUMAN ZIP KINASE IN COMPLEX WITH A TETRACYCLIC PYRIDONE INHIBITOR (PYRIDONE 6)
分子名称:DEATH-ASSOCIATED PROTEIN KINASE 3, 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, CHLORIDE ION, ...
著者Turnbull, A.P., Berridge, G., Fedorov, O., Pike, A.C.W., Savitsky, P., Eswaran, J., Papagrigoriou, E., Ugochukwa, E., von Delft, F., Gileadi, O., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2006-10-31
公開日2006-11-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
2JFL
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CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (DIPHOSPHORYLATED FORM) BOUND TO 5- AMINO-3-((4-(AMINOSULFONYL)PHENYL)AMINO)-N-(2,6- DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
分子名称:STE20-LIKE SERINE/THREONINE-PROTEIN KINASE, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, 1,2-ETHANEDIOL, ...
著者Pike, A.C.W., Rellos, P., Fedorov, O., Keates, T., Salah, E., Savitsky, P., Papagrigoriou, E., Bunkoczi, G., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2007-02-02
公開日2007-02-27
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
2JFM
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CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (UNLIGANDED FORM)
分子名称:STE20-LIKE SERINE-THREONINE KINASE, 1,2-ETHANEDIOL
著者Pike, A.C.W., Rellos, P., Fedorov, O., Keates, T., Salah, E., Savitsky, P., Papagrigoriou, E., Bunkoczi, G., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2007-02-02
公開日2007-02-27
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
2KBY
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THE TETRAMERIZATION DOMAIN OF HUMAN P73
分子名称:Tumor protein p73
著者Coutandin, D., Ikeya, T., Loehr, F., Guntert, P., Ou, H.D., Doetsch, V.
登録日2008-12-12
公開日2009-09-29
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Conformational stability and activity of p73 require a second helix in the tetramerization domain.
Cell Death Differ., 16, 2009
2P8U
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CRYSTAL STRUCTURE OF HUMAN 3-HYDROXY-3-METHYLGLUTARYL COA SYNTHASE I
分子名称:Hydroxymethylglutaryl-CoA synthase, cytoplasmic, COENZYME A, ...
著者Turnbull, A., Shafqat, N., Salah, E., Niesen, F.H., Burgess, N., Bunkoczi, G., Debreczeni, J., Pike, A.C.W., Umeano, C., Gorrec, F., von Delft, F., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-03-23
公開日2007-04-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
J.Mol.Biol., 398, 2010
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