Author results

2PYP
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PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Genick, U.K., Borgstahl, G.E.O., Ng, K., Ren, Z., Pradervand, C., Burke, P., Srajer, V., Teng, T., Schildkamp, W., Mcree, D.E., Moffat, K., Getzoff, E.D.
Deposit date:1997-02-03
Release date:1998-04-29
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a protein photocycle intermediate by millisecond time-resolved crystallography.
Science, 275, 1997
1KEX
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CRYSTAL STRUCTURE OF THE B1 DOMAIN OF HUMAN NEUROPILIN-1
Descriptor:Neuropilin-1
Authors:Lee, C.C., Kreusch, A., McMullan, D., Ng, K., Spraggon, G.
Deposit date:2001-11-18
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
1LM4
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STRUCTURE OF PEPTIDE DEFORMYLASE FROM STAPHYLOCOCCUS AUREUS AT 1.45 A
Descriptor:peptide deformylase PDF1, FE (III) ION, GLYCEROL
Authors:Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A.
Deposit date:2002-04-30
Release date:2003-06-24
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1LM6
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:peptide deformylase DEFB, FE (III) ION, GLYCEROL
Authors:Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A.
Deposit date:2002-04-30
Release date:2003-06-24
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1LME
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM THERMOTOGA MARITIMA
Descriptor:peptide deformylase
Authors:Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A., Joint Center for Structural Genomics (JCSG)
Deposit date:2002-05-01
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1N5N
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Peptide deformylase, ZINC ION, GLYCEROL
Authors:Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A.
Deposit date:2002-11-06
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1NH1
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CRYSTAL STRUCTURE OF THE TYPE III EFFECTOR AVRB FROM PSEUDOMONAS SYRINGAE.
Descriptor:Avirulence B protein
Authors:Lee, C.C., Wood, M.D., Ng, K., Luginbuhl, P., Spraggon, G., Katagiri, F.
Deposit date:2002-12-18
Release date:2004-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae.
Structure, 12, 2004
1ZLT
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CRYSTAL STRUCTURE OF CHK1 COMPLEXED WITH A HYMENALDISINE ANALOG
Descriptor:Serine/threonine-protein kinase Chk1, SULFATE ION, (4Z)-4-(2-AMINO-5-OXO-3,5-DIHYDRO-4H-IMIDAZOL-4-YLIDENE)-2,3-DICHLORO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8(1H)-ONE
Authors:Lee, C.C., Ng, K., Wan, Y., Gray, N., Spraggon, G.
Deposit date:2005-05-09
Release date:2006-06-27
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog
To be Published
2I7A
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DOMAIN IV OF HUMAN CALPAIN 13
Descriptor:Calpain 13, CALCIUM ION, SULFATE ION, ...
Authors:Walker, J.R., Ng, K., Davis, T.L., Ravulapalli, R., Butler-cole, C., Finerty Jr., P.J., Newman, E.M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-08-30
Release date:2006-09-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Calpain 13
To be Published
2ETM
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CRYSTAL STRUCTURE OF FOCAL ADHESION KINASE DOMAIN COMPLEXED WITH 7H-PYRROLO [2,3-D] PYRIMIDINE DERIVATIVE
Descriptor:Focal adhesion kinase 1, 7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE
Authors:Lee, C.C.
Deposit date:2005-10-27
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Focal Adhesion Kinase Domain Complexed with ATP and novel 7H-Pyrrolo [2,3-d] pyrimidine scaffolds
To be Published
2IJM
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CRYSTAL STRUCTURE OF FOCAL ADHESION KINASE DOMAIN WITH 2 MOLECULES IN THE ASYMMETRIC UNIT COMPLEXED WITH ADP AND ATP
Descriptor:Focal Adhesion Kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE
Authors:Lee, C.C.
Deposit date:2006-09-29
Release date:2007-08-14
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:Crystal Structure of Focal Adhesion Kinase Catalytic Domain Complexed with ATP and Novel 7H-Pyrrolo [2,3-d] pyrimidine Inhibitor Scaffolds
To be Published
3L9P
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CRYSTAL STRUCTURE OF THE ANAPLASTIC LYMPHOMA KINASE CATALYTIC DOMAIN
Descriptor:Anaplastic lymphoma kinase, GLYCEROL
Authors:Lee, C.
Deposit date:2010-01-05
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
3LCS
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CRYSTAL STRUCTURE OF THE ANAPLASTIC LYMPHOMA KINASE CATALYTIC DOMAIN
Descriptor:ALK tyrosine kinase receptor, STAUROSPORINE, GLYCEROL
Authors:Lee, C.C.
Deposit date:2010-01-11
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
3LCT
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CRYSTAL STRUCTURE OF THE ANAPLASTIC LYMPHOMA KINASE CATALYTIC DOMAIN
Descriptor:ALK tyrosine kinase receptor, GLYCEROL, ADENOSINE-5'-DIPHOSPHATE
Authors:Lee, C.C.
Deposit date:2010-01-11
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
5W5J
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IDENTIFICATION OF POTENT AND SELECTIVE RIPK2 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES
Descriptor:Receptor-interacting serine/threonine-protein kinase 2, N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide, SULFATE ION
Authors:Kreusch, A., Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
5W5O
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IDENTIFICATION OF POTENT AND SELECTIVE RIPK2 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES.
Descriptor:Receptor-interacting serine/threonine-protein kinase 2, 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine
Authors:Kreusch, A., Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
1S17
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IDENTIFICATION OF NOVEL POTENT BICYCLIC PEPTIDE DEFORMYLASE INHIBITORS
Descriptor:Peptide deformylase, NICKEL (II) ION, 2-(3,4-DIHYDRO-3-OXO-2H-BENZO[B][1,4]THIAZIN-2-YL)-N-HYDROXYACETAMIDE, ...
Authors:Molteni, V., He, X., Nabakka, J., Yang, K., Kreusch, A., Gordon, P., Bursulaya, B., Ryder, N.S., Goldberg, R., He, Y.
Deposit date:2004-01-05
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification of novel potent bicyclic peptide deformylase inhibitors
Bioorg.Med.Chem.Lett., 14, 2004